大東寛幸 (HIROYUKI OHIGASHI) - マイポータル

基本情報

所属: 北海道大学医学部血液内科

学位: 博士(2019年3月北海道大学)

研究者番号: 20845284
J-GLOBAL ID: 201901011934637655
researchmap会員ID: B000377009

研究分野

ライフサイエンス / 血液、腫瘍内科学 /

論文

Incidence and course of Epstein-Barr virus viremia after allogeneic hematopoietic stem cell transplant for adult-onset systemic chronic active Epstein-Barr virus disease.

Preeti Prerna M Vaswani, Masahiro Onozawa, Yuta Hasegawa, Hiroyuki Ohigashi, Takahide Ara, Toshihiro Matsukawa, Atsushi Yasumoto, Souichi Shiratori, Hideki Goto, Masao Nakagawa …

Bone marrow transplantation 2023年9月5日
Type 1 Cryoglobulinemic Vasculitis Due to Monoclonal Gammopathy of Undetermined Significance Successfully Treated by Bortezomib Plus Dexamethasone.

Ryo Kikuchi, Masahiro Onozawa, Jun Nagai, Satomi Okada, Yuta Hasegawa, Hiroyuki Ohigashi, Shintaro Mitamura, Taku Maeda, Emi Takakuwa, Yuichiro Fujieda …

Internal medicine (Tokyo, Japan) 2023年6月14日
Calcineurin inhibitor inhibits tolerance induction by suppressing terminal exhaustion of donor T cells after allo-HCT.

Hajime Senjo, Shinpei Harada, Shimpei I Kubota, Yuki Tanaka, Takahiro Tateno, Zixuan Zhang, Satomi Okada, Xuanzhong Chen, Ryo Kikuchi, Naoki Miyashita …

Blood 2023年5月22日
Subcutaneous Panniculitis-like T-cell Lymphoma Lacking Subcutaneous Tumor Mimicking Adult-onset Still's Disease.

Maria Tada, Shion Kachi, Masahiro Onozawa, Yuichiro Fujieda, Shota Yoshida, Yotaro Oki, Kazuro Kamada, Jun Nagai, Satomi Okada, Ryo Kikuchi …

Internal medicine (Tokyo, Japan) 2023年3月15日
Reactive granulopoiesis depends on T-cell production of IL-17A and neutropenia-associated alteration of gut microbiota.

Xuanzhong Chen, Daigo Hashimoto, Ko Ebata, Shuichiro Takahashi, Yu Shimizu, Ryuga Shinozaki, Yuta Hasegawa, Ryo Kikuchi, Hajime Senjo, Kazuki Yoneda …

Proceedings of the National Academy of Sciences of the United States of America 119(48) e2211230119 2022年11月29日
Neurolymphomatosis in Intravascular Large B-cell Lymphoma.

Toru Miyajima, Hiroyuki Ohigashi, Hiroaki Yaguchi, Takanori Teshima

Internal medicine (Tokyo, Japan) 2022年10月5日
Gilteritinib enhances graft-versus-leukemia effects against FLT3-ITD mutant leukemia after allogeneic hematopoietic stem cell transplantation.

Zixuan Zhang, Yuta Hasegawa, Daigo Hashimoto, Hajime Senjo, Ryo Kikuchi, Xuanzhong Chen, Kazuki Yoneda, Tomoko Sekiguchi, Tatsuya Kawase, Hirofumi Tsuzuki …

Bone marrow transplantation 57(5) 775-780 2022年5月
[Bing-Neel syndrome successfully treated with tirabrutinib].

Keito Yokoyama, Hiroyuki Ohigashi, Toru Miyajima, Naoki Miyashita, Satomi Okada, Yuta Hasegawa, Junichi Sugita, Masahiro Onozawa, Daigo Hashimoto, Takanori Teshima

[Rinsho ketsueki] The Japanese journal of clinical hematology 63(8) 870-875 2022年
Aleukemic Extramedullary Blast Crisis as an initial presentation of Chronic Myeloid Leukemia with E1A3 BCR-ABL1 Fusion Transcript.

Naoki Miyashita, Masahiro Onozawa, Keito Suto, Shinichi Fujisawa, Nanase Okazaki, Daisuke Hidaka, Hiroyuki Ohigashi, Atsushi Yasumoto, Junichi Sugita, Daigo Hashimoto …

Internal medicine (Tokyo, Japan) 61(7) 1049-1054 2021年9月11日査読有り
High lymphocyte counts before antithymocyte globulin administration predict acute graft-versus-host disease.

Souichi Shiratori, Hiroyuki Ohigashi, Takahide Ara, Atsushi Yasumoto, Hideki Goto, Masao Nakagawa, Junichi Sugita, Masahiro Onozawa, Kaoru Kahata, Tomoyuki Endo …

Annals of hematology 100(5) 1321-1328 2021年5月査読有り
Intestinal goblet cells protect against GVHD after allogeneic stem cell transplantation via Lypd8.

Takahide Ara, Daigo Hashimoto, Eiko Hayase, Clara Noizat, Ryo Kikuchi, Yuta Hasegawa, Kana Matsuda, Shoko Ono, Yoshihiro Matsuno, Ko Ebata …

Science translational medicine 12(550) 2020年7月1日査読有り
Short-term KRP203 and posttransplant cyclophosphamide for graft-versus-host disease prophylaxis.

Emi Yokoyama, Daigo Hashimoto, Eiko Hayase, Takahide Ara, Reiki Ogasawara, Shuichiro Takahashi, Hiroyuki Ohigashi, Takahiro Tateno, Yuta Hasegawa, Xuanzhong Chen …

Bone marrow transplantation 55(4) 787-795 2020年4月査読有り
Reduced dose of MTX for GVHD prophylaxis promotes engraftment and decreases non-relapse mortality in umbilical cord blood transplantation.

Souichi Shiratori, Hiroyuki Ohigashi, Shuichiro Takahashi, Takahide Ara, Hideki Goto, Masao Nakagawa, Junichi Sugita, Masahiro Onozawa, Kaoru Kahata, Tomoyuki Endo …

Annals of hematology 99(3) 591-598 2020年3月査読有り
Salvage Transplantation with Cord Blood for Graft Rejection of Peripheral Blood Stem Cells due to Donor Specific Antibody

Maria Regina Pelobello de Leon, Shuichiro Takahashi, Masahiro Onozawa, Makoto Ito, Manabu Nakano, Hajime Senjo, Masahiro Chiba, Hiroyuki Ohigashi, Emi Yokoyama, Junichi Sugita …

BLOOD CELL THERAPY / The official journal of APBMT 3(3) 74-77 2020年査読有り
Myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease.

Satomi Matsuoka, Daigo Hashimoto, Masanori Kadowaki, Hiroyuki Ohigashi, Eiko Hayase, Emi Yokoyama, Yuta Hasegawa, Takahiro Tateno, Xuanzhong Chen, Kazutoshi Aoyama …

Haematologica 105(1) 226-234 2020年1月査読有り
Ocular instillation of vitamin A-coupled liposomes containing HSP47 siRNA ameliorates dry eye syndrome in chronic GVHD.

Hiroyuki Ohigashi, Daigo Hashimoto, Eiko Hayase, Shuichiro Takahashi, Takahide Ara, Tomohiro Yamakawa, Junichi Sugita, Masahiro Onozawa, Masao Nakagawa, Takanori Teshima

Blood advances 3(7) 1003-1010 2019年4月9日査読有り筆頭著者
Intestinal Lymphatic Endothelial Cells Produce R-Spondin3.

Reiki Ogasawara, Daigo Hashimoto, Shunsuke Kimura, Eiko Hayase, Takahide Ara, Shuichiro Takahashi, Hiroyuki Ohigashi, Kosuke Yoshioka, Takahiro Tateno, Emi Yokoyama …

Scientific reports 8(1) 10719-10719 2018年7月16日査読有り
Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease.

Shuichiro Takahashi, Daigo Hashimoto, Eiko Hayase, Reiki Ogasawara, Hiroyuki Ohigashi, Takahide Ara, Emi Yokoyama, Ko Ebata, Satomi Matsuoka, Geoffrey R Hill …

Blood 131(18) 2074-2085 2018年5月3日査読有り
Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease.

Tomohiro Yamakawa, Hiroyuki Ohigashi, Daigo Hashimoto, Eiko Hayase, Shuichiro Takahashi, Miyono Miyazaki, Kenjiro Minomi, Masahiro Onozawa, Yoshiro Niitsu, Takanori Teshima

Blood 131(13) 1476-1485 2018年3月29日査読有り筆頭著者
R-Spondin1 expands Paneth cells and prevents dysbiosis induced by graft-versus-host disease.

Eiko Hayase, Daigo Hashimoto, Kiminori Nakamura, Clara Noizat, Reiki Ogasawara, Shuichiro Takahashi, Hiroyuki Ohigashi, Yuki Yokoi, Rina Sugimoto, Satomi Matsuoka …

The Journal of experimental medicine 214(12) 3507-3518 2017年12月4日査読有り

もっとみる

MISC

クローン病に対しインフリキシマブ治療歴のある肝脾T細胞リンパ腫に対して臍帯血移植を施行した1例

鈴木陶磨, 大東寛幸, 宮下直樹, 須藤啓斗, 日高大輔, 小笠原励起, 杉田純一, 小野澤真弘, 橋本大吾, 豊嶋崇徳

日本造血・免疫細胞療法学会総会プログラム・抄録集 44th 2022年
Letermovir Is Effective for Prevention of Cytomegalovirus Reactivation in HLA-Haploidentical Peripheral Blood Stem Cell Transplantation with Post-Transplant Cyclophosphamide

Takahide Ara, Yuta Hasegawa, Hiroyuki Ohigashi, Souichi Shiratori, Atsushi Yasumoto, Hideki Goto, Junichi Sugita, Masahiro Onozawa, Masao Nakagawa, Kaoru Kahata …

BLOOD 138 2021年11月
同種造血幹細胞移植後の体液貯留は予後不良である

宮下直樹, 須藤啓斗, 日高大輔, 大東寛幸, 荒隆英, 白鳥聡一, 安本篤史, 後藤秀樹, 杉田純一, 小野澤真弘 …

日本造血細胞移植学会総会プログラム・抄録集 43rd 2021年