胡キン (Xin Hu) - マイポータル

基本情報

所属: 国立研究開発法人国立成育医療研究センター移植免疫研究室研究員

研究者番号: 40868965
J-GLOBAL ID: 202301015144474517
researchmap会員ID: R000060781

研究分野

経歴

2020年 - 現在

国立研究開発法人国立成育医療研究センター, RI管理室・移植免疫研究室, 研究員
2017年 - 2019年

独立行政法人日本学術振興会 (外国人特別研究員)
2016年 - 2018年

国立研究開発法人国立成育医療研究センター, RI管理室・移植免疫研究室, 共同研究員

学歴

2012年 - 2016年

千葉大学, 大学院医学薬学府

受賞

2021年

最もダウンロード, Wileyジャーナル

論文

Targeted immune cell therapy for hepatocellular carcinoma using expanded liver mononuclear cell-derived natural killer cells.

Xin Hu, Yifang Shui, Seiichi Shimizu, Seisuke Sakamoto, Mureo Kasahara, Seiji Okada, Wen-Zhi Guo, Masayuki Fujino, Xiao-Kang Li

Neoplasia (New York, N.Y.) 58 101061-101061 2024年10月1日
Coral calcium carried hydrogen ameliorates the severity of non-alcoholic steatohepatitis induced by a choline deficient high carbohydrate fat-free diet in elderly rats

Kuai Ma, Xin Hu, Keiki Nambu, Daisuke Ueda, Naotsugu Ichimaru, Masayuki Fujino, Xiao Kang Li

Scientific Reports 13(1) 2023年12月
Temporal and spatial dynamics of immune cells in spontaneous liver transplant tolerance

Weitao Que, Hisashi Ueta, Xin Hu, Miwa Morita-Nakagawa, Masayuki Fujino, Daisuke Ueda, Nobuko Tokuda, Wenxin Huang, Wen Zhi Guo, Lin Zhong …

iScience 26(9) 2023年9月15日
Combined phospholipids adjuvant augments anti-tumor immune responses through activated tumor-associated dendritic cells

Yifang Shui, Xin Hu, Hiroshi Hirano, Hirotake Tsukamoto, Wen Zhi Guo, Kenichiro Hasumi, Fumihiro Ijima, Masayuki Fujino, Xiao Kang Li

Neoplasia (United States) 39 2023年5月
PD-L1 antibody enhanced β-glucan antitumor effects via blockade of the immune checkpoints in a melanoma model

Xin Hu, Yifang Shui, Hiroshi Hirano, Kisato Kusano, Wen Zhi Guo, Masayuki Fujino, Xiao Kang Li

Cancer Immunology, Immunotherapy 72(3) 719-731 2023年3月
Combinations of anti-GITR antibody and CD28 superagonist induce permanent allograft acceptance by generating type 1 regulatory T cells

Weitao Que, Kuai Ma, Xin Hu, Wen Zhi Guo, Xiao Kang Li

Science Advances 8(31) 2022年8月
Combinations of anti-GITR antibody and CD28 superagonist ameliorated dextran sodium sulfate-induced mouse colitis

Kuai Ma, Weitao Que, Xin Hu, Wen Zhi Guo, Liang Zhong, Daisuke Ueda, Er Li Gu, Xiao Kang Li

Clinical and Experimental Immunology 208(3) 340-350 2022年6月
A Mesenchymal-Epithelial Transition Factor-Agonistic Antibody Accelerates Cirrhotic Liver Regeneration and Improves Mouse Survival Following Partial Hepatectomy

Kuai Ma, Weitao Que, Xin Hu, Wen Zhi Guo, Er li Gu, Liang Zhong, Virginia Morello, Manuela Cazzanti, Paolo Michieli, Terumi Takahara …

Liver Transplantation 28(5) 782-793 2022年5月
β-glucan from Aureobasidium pullulans augments the anti-tumor immune responses through activated tumor-associated dendritic cells

Yifang Shui, Xin Hu, Hiroshi Hirano, Kisato Kusano, Hirotake Tsukamoto, Mengquan Li, Kenichiro Hasumi, Wen Zhi Guo, Xiao Kang Li

International Immunopharmacology 101 2021年12月
Oridonin Prolongs the Survival of Mouse Cardiac Allografts by Attenuating the NF-κB/NLRP3 Pathway

Xiaoxiao Du, Weitao Que, Xin Hu, Xiao Yu, Wen Zhi Guo, Shuijun Zhang, Xiao Kang Li

Frontiers in Immunology 12 2021年9月10日
5-aminolevulinic acid combined with sodium ferrous citrate ameliorated lupus nephritis in a mouse chronic graft-versus-host disease model

Chi Liu, Zhidan Wang, Xin Hu, Hidenori Ito, Kiwamu Takahashi, Motowo Nakajima, Tohru Tanaka, Ping Zhu, Xiao Kang Li

International Immunopharmacology 96 2021年7月
5-Aminolevulinic acid/sodium ferrous citrate enhanced the antitumor effects of programmed cell death-ligand 1 blockade by regulation of exhausted T cell metabolism in a melanoma model

Xin Hu, Weitao Que, Hiroshi Hirano, Zhidan Wang, Naoko Nozawa, Takuya Ishii, Masahiro Ishizuka, Hidenori Ito, Kiwamu Takahashi, Motowo Nakajima …

Cancer Science 112(7) 2652-2663 2021年7月
Prolonged Cold Ischemia Time in Mouse Heart Transplantation Using Supercooling Preservation

Weitao Que, Xin Hu, Masayuki Fujino, Hayato Terayama, Kou Sakabe, Nahoko Fukunishi, Ping Zhu, Shuang Qin Yi, Yoshio Yamada, Lin Zhong …

Transplantation 104(9) 1879-1889 2020年9月1日
Low-dose hyperthermia enhances the antitumor effects of chemotherapy in squamous cell carcinoma

X. Hu, Yasunori Akutsu, A. Suganami, W. Qin, N. Hanari, K. Murakam, M. Kano, A. Usui, H. Suito, M. Takahashi …

Diseases of the Esophagus 30(7) 2017年7月1日
Modulated electro-hyperthermia enhances dendritic cell therapy through an abscopal effect in mice

Wei Qin, Yasunori Akutsu, Gabor Andocs, Akiko Suganami, Xin Hu, Gulbostan Yusup, Aki Komatsu-Akimoto, Isamu Hoshino, Naoyuki Hanari, Mikito Mori …

Oncology Reports 32(6) 2373-2379 2014年12月1日
A COX-2 inhibitor enhances the antitumor effects of chemotherapy and radiotherapy for esophageal squamous cell carcinoma

Gulbostan Yusup, Yasunori Akutsu, Muradil Mutallip, Wei Qin, Xin Hu, Aki Komatsu-Akimoto, Isamu Hoshino, Naoyuki Hanari, Mikito Mori, Naoki Akanuma …

International Journal of Oncology 44(4) 1146-1152 2014年4月
The effect of stress on efficacy of dendritic cell therapy for esophageal squamous cell carcinoma.

Takeshi Toyozumi, Naoki Akanuma, Masahiko Takahashi, Isamu Hoshino, Xin Hu, Naoyuki Hanari, Yasunori Akutsu, Mikito Mori, Yuka Isozaki, Kentaro Murakami …

Journal of Clinical Oncology 32 69-69 2014年1月20日
MicroRNA-133a regulates the mRNAs of two invadopodia-related proteins, FSCN1 and MMP14, in esophageal cancer

N. Akanuma, I. Hoshino, Y. Akutsu, K. Murakami, Y. Isozaki, T. Maruyama, G. Yusup, W. Qin, T. Toyozumi, M. Takahashi …

British Journal of Cancer 110(1) 189-198 2014年

講演・口頭発表等

複合リン脂質アジュバントの活性化腫瘍関連樹状細胞を介して抗腫瘍免疫応答を増強する効果

第82回日本癌学会学術集会
Supercooling preservation prolonged cold ischemia time in mouse heart transplantation

第48回日本臓器保存生物医学会学術集会
Liver mononuclear cells-derived NK cells for treatment of hepatocellular carcinoma

第51回日本免疫学会学術集会
PD-L1 antibody enhanced the β-glucan antitumor effects via blockade the immune checkpoints in melanoma model

第81回日本癌学会学術集会
Enhancement of antitumor effects of PD-L1 blockade by 5-ALA/SFC via upregulation of metabolism in exhausted T cells in murine melanoma model

第80回日本癌学会学術集会
5-Aminolevulinic acid with sodium ferrous citrate enhance the antitumor effects of PD-L1 blockade in mouse melanoma model

7th International ALA and Porphyrin Symposium
5-Aminolevulinic acid with sodium ferrous citrate enhances the antitumor effects of PD-L1 blockade in experimental melanoma model

第48回日本免疫学会学術集会

所属学協会

共同研究・競争的資金等の研究課題

The research of characterization and functional analysis of novel immune cells in tumor immune escape mechanisms

日本学術振興会科学研究費助成事業基盤研究(C) 2025年4月 - 2028年3月

Hu Xin
The research of targeting tumor-associated dendritic cells, a new therapy strategy by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists 2023年4月 - 2025年3月
The research of targeting tumor-associated macrophages, a new combination therapy strategy by macrophage polarization and immune checkpoint blockade

Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists 2021年4月 - 2023年3月
新規急速液体凍結法「凍眠」を用いた移植用臓器保存法の確立およびその機序の解明

日本学術振興会科学研究費助成事業特別研究員奨励費 2018年4月 - 2020年3月

梨井康, HU XIN

胡キン

基本情報

研究分野

経歴

学歴

受賞

論文

講演・口頭発表等

所属学協会

共同研究・競争的資金等の研究課題

メニュー

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