Hidefumi Waki

Profile Information

Affiliation: Professor (Dean), Graduate School of Health and Sports Science, Juntendo University

Degree: 博士（医学）(福島県立医科大学)

J-GLOBAL ID: 201801008051292374
researchmap Member ID: B000332685

Research Areas

Papers

106

Involvement of D1 dopamine receptor in the nucleus of the solitary tract of rats in stress-induced hypertension and exercise.

Ko Yamanaka, Makoto Suzuki, Linh Thuy Pham, Keisuke Tomita, Thu Van Nguyen, Miwa Takagishi, Kei Tsukioka, Sabine Gouraud, Hidefumi Waki

Journal of hypertension, Jul 5, 2024
Functional connectivity in central nucleus of amygdala, paraventricular hypothalamus, and nucleus tractus solitarii circuits during high-intensity endurance treadmill exercise in rats

Shinichiro Ezure, Hiroyasu Ichihara, Ko Yamanaka, Hidefumi Waki

The Journal of Physical Fitness and Sports Medicine, 12(3) 69-75, May 25, 2023
Impact of exercise on brain-bone marrow interactions in chronic stress: potential mechanisms preventing stress-induced hypertension.

Thu Van Nguyen, Ko Yamanaka, Keisuke Tomita, Jasenka Zubcevic, Sabine S S Gouraud, Hidefumi Waki

Physiological genomics, 55(5) 222-234, May 1, 2023
Implication of the central nucleus of the amygdala in cardiovascular regulation and limiting maximum exercise performance during high-intensity exercise in rats.

Kei Tsukioka, Ko Yamanaka, Hidefumi Waki

Neuroscience, Jun 8, 2022
運動時の情動と心血管応答制御における扁桃体中心核の役割

山中航, 月岡惠惟, 和気秀文

自律神経, 59(2) 244-244, Jun, 2022
Conditional Regulation of Blood Pressure in Response to Emotional Stimuli by the Central Nucleus of the Amygdala in Rats

Ko Yamanaka, Hidefumi Waki

Frontiers in Physiology, 13, Jun 1, 2022
Estradiol-dependent gene expression profile in the amygdala of young ovariectomized spontaneously hypertensive rats.

Linh T Pham, Ko Yamanaka, Yasunori Miyamoto, Hidefumi Waki, Sabine S S Gouraud

Physiological genomics, 54(3) 99-114, Mar 1, 2022
運動時の情動と心血管応答制御における扁桃体中心核の役割

山中航, 月岡惠惟, 和気秀文

日本自律神経学会総会プログラム・抄録集, 74回 101-101, Oct, 2021
Regional brain gray matter volume in world-class artistic gymnasts

Makoto Fukuo, Koji Kamagata, Mana Kuramochi, Christina Andica, Hiroyuki Tomita, Hidefumi Waki, Hidenori Sugano, Yuichi Tange, Takumi Mitsuhashi, Wataru Uchida …

JOURNAL OF PHYSIOLOGICAL SCIENCES, 70(1), Sep, 2020
Potential Role of the Amygdala and Posterior Claustrum in Exercise Intensity-dependent Cardiovascular Regulation in Rats.

Jimmy Kim, Ko Yamanaka, Kei Tsukioka, Hidefumi Waki

Neuroscience, Feb 26, 2020 Peer-reviewed
White Matter Myelin Changes Related to Long-term Intensive Training in Japanese World-class Gymnasts

CHRISTINA ANDICA, HIROYUKI TOMITA, KOJI KAMAGATA, WATARU UCHIDA, SYO MURATA, AKIFUMI HAGIWARA, MAKOTO FUKUO, HIDEFUMI WAKI, HIDENORI SUGANO, YUICHI TANGE …

Juntendo Medical Journal, 66(Suppl.1) 21-28, 2020
Effects of bilateral lesions in the central amygdala on spontaneous baroreceptor reflex in conscious rats

Tsukioka Kei, Yamanaka Ko, Waki Hidefumi

The Journal of Physical Fitness and Sports Medicine, 8(1) 45-50, 2019
Bidirectional cardiovascular responses evoked by microstimulation of the amygdala in rats

Ko Yamanaka, Miwa Takagishi, Jimmy Kim, Sabine S. Gouraud, Hidefumi Waki

Journal of Physiological Sciences, 68(3) 233-242, May 1, 2018 Peer-reviewed
Impact of heart-specific disruption of the circadian clock on systemic glucose metabolism in mice

Tomomi Nakao, Akira Kohsaka, Tsuyoshi Otsuka, Zaw Lin Thein, Hue Thi Le, Hidefumi Waki, Sabine S Gouraud, Hayato Ihara, Masako Nakanishi, Fuyuki Sato …

Chronobiology International, 35(4) 499-510, Apr 3, 2018 Peer-reviewed
Trpv4 involvement in the sex differences in blood pressure regulation in spontaneously hypertensive rats

Makiko Onishi, Ko Yamanaka, Yasunori Miyamoto, Hidefumi Waki, Sabine Gouraud

Physiological Genomics, 50(4) 263-271, Apr 1, 2018
Trpv4 involvement in the sex differences in blood pressure regulation in spontaneously hypertensive rats.

Onishi M, Yamanaka K, Miyamoto Y, Waki H, Gouraud S

Physiological genomics, 50(4) 272-286, Apr, 2018 Peer-reviewed
Involvement of the Caudal Part of Insular Cortex and Central Nucleus of the Amygdala in Cardiovascular Regulation During Exhausting Exercise

KIM JIMMY, YAMANAKA KO, TSUKIOKA KEI, TAKAGISHI MIWA, GOURAUD SABINE S., WAKI HIDEFUMI

Juntendo Medical Journal, 64(1) 81-82, 2018
Combined long-term caffeine intake and exercise inhibits the development of diabetic nephropathy in OLETF rats

Masato Suzuki, Daisuke Shindo, Ryuichiro Suzuki, Yoshiaki Shirataki, Hidefumi Waki

JOURNAL OF APPLIED PHYSIOLOGY, 122(5) 1321-1328, May, 2017 Peer-reviewed
Evidence for a histaminergic input from the ventral tuberomammillary nucleus to the solitary tract nucleus involved in arterial pressure regulation

Ko Yamanaka, Sabine S. Gouraud, Miwa Takagishi, Akira Kohsaka, Masanobu Maeda, Hidefumi Waki

Physiological Reports, 5(5), Mar 1, 2017 Peer-reviewed
Systemic leukotriene B-4 receptor antagonism lowers arterial blood pressure and improves autonomic function in the spontaneously hypertensive rat

Paul J. Marvar, Emma B. Hendy, Thomas D. Cruise, Dawid Walas, Danielle DeCicco, Rajanikanth Vadigepalli, James S. Schwaber, Hidefumi Waki, David Murphy, Julian F. R. Paton

JOURNAL OF PHYSIOLOGY-LONDON, 594(20) 5975-5989, Oct, 2016 Peer-reviewed

Misc.

153

ストレス性高血圧における扁桃体STAT3の役割

和気秀文, 冨田圭祐, 月岡惠惟, NGUYEN Van Thu, GOURAUD Sabine, 山中航

高血圧関連疾患モデル学会学術総会抄録集, 56th, 2020
拘束ストレスラットに対する運動介入が延髄孤束核における神経伝達系因子に及ぼす影響

和気秀文, 鈴木誠, 冨田圭佑, 山中航, 月岡惠惟, SABINE Gouraud

日本循環薬理学会口演要旨集, 29th, 2019
高強度トレッドミル運動遂行中の循環調節における扁桃体と島皮質の役割

山中航, KIM Jimmy, KIM Jimmy, 月岡惠惟, 月岡惠惟, 和気秀文

日本循環薬理学会口演要旨集, 29th, 2019
ストレス性高血圧における扁桃体遺伝子発現と運動による修飾作用

和気秀文, 冨田圭佑, 山中航, 月岡惠惟, 鈴木誠, グホサビン

高血圧関連疾患モデル学会学術総会抄録集, 54th, 2018
運動やスポーツに対するモチベーションが脳内報酬系および行動に与える影響

山中航, 川田裕次郎, 和気秀文

順天堂スポーツ健康科学研究, 8(Supplement) 4-4, Mar 31, 2017
麻酔下および覚醒ラットにおける扁桃体の循環応答制御―ストレスが高血圧を発症させるしくみの解明に向けて―

山中航, 高岸美和, 金芝美, SABINE Gouraud, 和気秀文

高血圧関連疾患モデル学会学術総会抄録集, 53rd (Web) 63 (WEB ONLY), 2017
高血圧における神経科学的研究の現在と展望

和気秀文, 山中航, SABINE Gouraud

高血圧関連疾患モデル学会学術総会抄録集, 53rd (Web) 17 (WEB ONLY), 2017
スポーツは子どもの脳を育む発育期の運動習慣が心臓血管中枢へ及ぼす影響生活習慣病予防効果の新しい機序

和気秀文, 山中航, 内藤久士

脳と発達, 48(Suppl.) S107-S107, May, 2016
女性アスリートのためのスポーツ医学を考える女性トップアスリートに対する医科学サポート疲労骨折を中心に

櫻庭景植, 藤田真平, 窪田淳之, 鯉川なつえ, 和気秀文, 鈴木良雄, 山澤文裕

体力科学, 65(1) 28-28, Feb, 2016
女性トップアスリートに対する医科学サポート ~疲労骨折を中心に~

櫻庭景植, 櫻庭景植, 藤田真平, 窪田淳之, 鯉川なつえ, 和気秀文, 鈴木良雄, 山澤文裕

体力科学, 65(1) 28‐28 (J‐STAGE)-28, 2016
扁桃体の局所電気刺激が循環応答に及ぼす影響

山中航, 高岸美和, GOURAUD Sobine, 和気秀文

体力科学, 64(6) 548-548, Dec 1, 2015
扁桃体昇圧部による圧受容器反射制御

和気秀文, 山中航, 高岸美和, GOURAUD Sabine

体力科学, 64(6) 549-549, Dec 1, 2015
高血圧ラットの延髄由来培養アストロサイトにおける遺伝子発現プロファイル

GOURAUD Sabine, 大西真紀子, 橋本恵, 宮本泰則, 山中航, 和気秀文

体力科学, 64(6) 575-575, Dec 1, 2015
心臓の時計遺伝子機能と耐糖能異常の関係

向阪彰, 中尾友美, グホサビン, 和気秀文, 前田正信

日本内分泌学会雑誌, 91(1) 320-320, Apr 1, 2015
糖尿病発症における心臓の時計遺伝子の関与について

中尾友美, 向阪彰, 北内真理子, 小形光, サビングホ, 和気秀文, 前田正信

日本生理学雑誌, 77(1 (Web)) WEB ONLY-16, Jan, 2015
扁桃体局所電気刺激による循環応答の多様性

和気秀文, 山中航, 高岸美和, SABINE Gouraud

高血圧関連疾患モデル学会学術総会抄録集, 51st 46, 2015
運動時循環応答の中枢性機序視床下部結節乳頭核延髄孤束核経路の役割

和気秀文

体力科学, 63(6) 576-576, Dec, 2014
自発的運動を課した2型糖尿病ラットにおける運動パフォーマンスと筋組成、筋酵素活性について

高田義弘, 竹下大輔, 花岡智子, 奥田俊詞, 鷲尾弘枝, 石見恵子, 保井俊英, 今北英高, 峯松亮, 星野聡子 …

体力科学, 63(6) 720-720, Dec, 2014
視床下部結節乳頭核-延髄孤束核経路は運動時の昇圧反応に関与する

和気秀文

日本循環制御医学会総会プログラム・抄録集, 35回 54-54, Jul, 2014
自発的運動により2型糖尿病の発症が抑制されたOLETFラットの運動パフォーマンスと骨格筋特性

高田義弘, 竹下大輔, 石見惠子, 保井俊英, 今北英高, 峯松亮, 和気秀文, 岡田修一, 平川和文, 中谷昭 …

体力科学, 63(3) 356-357, Jun, 2014

Research Projects

妊娠中の運動による視床下部結節乳頭核―延髄孤束核系を介した中枢性循環調節機序

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2022 - Mar, 2025

板倉敦夫, 和気秀文
Effects of oral exposure to nanoplastics on inflammatory response and autonomic nervous function of the area postrema

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2024
Brain-bone marrow interaction in stress-induced hypertension and the protective effects of exercise training

Grants-in-Aid for Scientific Research, Fund for the Promotion of Joint International Research (Fostering Joint International Research (B)), Japan Society for the Promotion of Science, Oct, 2019 - Mar, 2024
ストレス性高血圧の発症と運動による予防・改善効果に関わる扁桃体STAT3の役割

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2019 - Mar, 2023

和気秀文, グホサビン, 山中航
Functional MRI and diffusion MRI analysis of motor function plasticity and networks utilizing machine learning.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

TANGE YUICHI
Sex differences in blood pressure regulation - elucidation of the central mechanisms of hypotension in females -

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Gouraud Sabine
The circadian clock maintains cardiac function by regulating mitochondrial metabolism in mice

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Kohsaka Akira, Waki Hidefumi, Gouraud Sabine, Otsuka Tsuyoshi
Central mechanisms of cardiovascular regulation during exercise -potential role of the TMN and NTS-

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

WAKI Hidefumi, KOHSAKA Akira, GOURAUD Sabine
Metabolic Cycles Are Linked to the Cardiovascular Diurnal Rhythm in Rats with Essential Hypertension

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2010 - 2012

KOHSAKA Akira, MAEDA Masanobu, WAKI Hidefumi, GOURAUD Sabine
Central mechanisms underlying antihypertensive effects of daily exercise in hypertension

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2009 - 2011

WAKI Hidefumi, MAEDA Masanobu, KOHSAKA Akira, GOURAUD Sabine
Prediction of graft patency by the analysis of transit-time flow meter waveform in coronary artery bypass grafting.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2008 - 2011

OKAMURA Yoshitaka, KANEKO Masahiro, MAEDA Masanobu, WAKI Hidefumi, HATADA Atsutoshi
Direct delivery of vascular endothelial growth factor improves heart failure in rats' myocardial infarction model.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2008 - 2010

TOGUCHI Koji, KANEKO Masahiro, HIRAMATSU Takeshi, OKAMURA Yoshitaka, MAEDA Masanobu, WAKI Hidefumi, KOHSAKA Akira, NISHIMURA Yoshiharu, HATADA Atsutoshi
Direct injection of neuronal nitric oxide synthase into the nucleus tractus soitarii in rats and development of protein therapy

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2008 - 2010

MAEDA Masanobu, WAKI Hidefumi, KOHSAKA Akira
Role of Prokineticin 2 in the Neural Regulation of Blood Pressure in Rats

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (Start-up), Japan Society for the Promotion of Science, 2008 - 2009

KOHSAKA Akira, MAEDA Masanobu, WAKI Hidefumi, CUI He, BHUIYAN Mohammad
Specific inflammatory condition in the nucleus tractus solitarii and human essential hypertension

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2007 - 2008

WAKI Hidefumi, MAEDA Masanobu
Effects of direct transduction of neuronal nitric oxide synthase protein into the nucleus tractus solitarius on circulation

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2006 - 2007

MAEDA Masanobu, YUKAWA Kazunori, WAKI Hidefumi, KOHDA Ken, KOHSAKA Akira
微小重力下におけるラット大動脈神経性圧受容器反射機構の生後発達

科学研究費助成事業, 基盤研究(A), 日本学術振興会, 1996 - 1999

清水強, 和気秀文, 永山忠徳, 山崎将生, 片平清昭, 勝田新一郎

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