安川秀雄 (Hideo Yasukawa) - マイポータル - researchmap

基本情報

所属: 久留米大学保健管理センター教授 (センター長)

研究者番号: 60289361
J-GLOBAL ID: 200901058878590585
researchmap会員ID: 1000209162

外部リンク: https://www.kurume-shinzo.com/

研究キーワード

2

研究分野

1

ライフサイエンス / 分子生物学 /

学歴

4

MISC

25

SOCS3 is a physiological negative regulator for granulopoiesis and G-CSF receptor signaling (J Biol Chem).

2004年
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

H Yasukawa, M Ohishi, H Mori, M Murakami, T Chinen, D Aki, T Hanada, K Takeda, S Akira, M Hoshijima …

NATURE IMMUNOLOGY 4(6) 551-556 2003年6月
The suppressors of cytokine signaling-1 (SOCS1) is a novel therapeutic target for enterovirus-induced cardiac injury (J Clin Invest).

2003年
The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6

A Sasaki, K Inagaki-Ohara, T Yoshida, A Yamanaka, M Sasaki, H Yasukawa, AE Koromilas, A Yoshimura

JOURNAL OF BIOLOGICAL CHEMISTRY 278(4) 2432-2436 2003年1月
The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy (Cell).

2002年
Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways (J Clin Invest).

2001年
Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 is involved in gp130 resistance in cardiovascular system in rat treated with cardiotrophin-1 in vivo. (Circ Res).

2001年
A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through SOCS box (J Biol Chem).

2001年
A SOCS-box of SOCS1 accelerates ubiquitination and proteasome-dependent degradation of TEL-JAK2 (J Biol Chem).

2001年
Negative regulation of the cytokine signaling pathways (Annu Rev Immunol).

2000年
CIS3/SOCS-3 Suppresses Erythropoietin (EPO) Signaling by Binding the EPO Receptor and JAK2 (J Biol Chem).

2000年
Role of the JAK/STAT pathway in rat carotid artery remodeling after vascular injury (Circ Res).

2000年
The JAK-Binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop (EMBO J).

1999年
SOCS-3 is Essential in the Regulation of Fetal Liver Erythropoiesis. (Cell).

1999年
Endothelial injuries of coronary arteries distal to thrombotic sites: role of adhesive interaction between endothelial p-selectin and leukocyte sialyl lewisX. (Circ Res).

1999年
Adhesive Interaction between p-selectin and sialyl lewis X plays an important role in recurrent coronary arterial thrombosis in dogs (Arterioscler Thromb Vasc Biol).

1999年
A Janus kinase inhibitor, JAB, is an interferon-gamma inducible gene and confers resistance to interferons (Blood).

1998年
Expression of stem cell factor in human aortic endothelial and smooth muscle cells

T Miyamoto, Y Sasaguri, T Sasaguri, S Azakami, H Yasukawa, S Kato, N Arima, K Sugama, M Morimatsu

ATHEROSCLEROSIS 129(2) 207-213 1997年3月
Inhibition of intimaL hyperplasia after balloon injury by antibodies to intercellular adhesion molecule-1 and lymphocyte function-associated antigen-1 (Circulation).

1997年
Asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in experimental hypertension

H Matsuoka, S Itoh, M Kimoto, K Kohno, O Tamai, Y Wada, H Yasukawa, G Iwami, S Okuda, T Imaizumi

HYPERTENSION 29(1) 242-247 1997年1月

もっとみる

書籍等出版物

2

所属学協会

2

Works(作品等)

1

シグナル伝達制御因子SOCSの作用機構の解明、ウイルス性心筋炎におけるJAK/STAT/SOCS系の機能解析、炎症におけるマクロファージSOCS3の機能解析

共同研究・競争的資金等の研究課題

4