2010
Preparation and chiral recognition of polysaccharide-based selectors
Chiral Recognition in Separation Methods: Mechanisms and Applications
- ,
- First page
- 33
- Last page
- 52
- Language
- English
- Publishing type
- Part of collection (book)
- DOI
- 10.1007/978-3-642-12445-7_2
- Publisher
- Springer Berlin Heidelberg
Among more than one hundred commercially available CSPs, those based on the phenylcarbamates of polysaccharides including cellulose and amylose have been recognized as the most powerful for the resolution of a wide range of racemates, and nearly 90% of chiral compounds can be resolved at the analytical level using the polysaccharide-based CSPs. Although the qualitative understanding of the chiral recognition mechanism of polysaccharide-based CSPs is rather difficult in contrast to the small molecule-based CSPs, several attempts have made for comprehension of the chromatographic behavior on the polysaccharide-based CSPs. In this chapter, after describing the development of the polysaccharide-based CSPs with high recognition ability, special emphasis is placed on the mechanistic study of the polysaccharide-based CSPs on the basis of spectroscopic and computational methods. © 2010 Springer-Verlag Berlin Heidelberg.
- Link information
- ID information
-
- DOI : 10.1007/978-3-642-12445-7_2
- SCOPUS ID : 84895236541