Papers

Peer-reviewed Lead author
2010

Preparation and chiral recognition of polysaccharide-based selectors

Chiral Recognition in Separation Methods: Mechanisms and Applications
  • Tomoyuki Ikai
  • ,
  • Yoshio Okamoto

First page
33
Last page
52
Language
English
Publishing type
Part of collection (book)
DOI
10.1007/978-3-642-12445-7_2
Publisher
Springer Berlin Heidelberg

Among more than one hundred commercially available CSPs, those based on the phenylcarbamates of polysaccharides including cellulose and amylose have been recognized as the most powerful for the resolution of a wide range of racemates, and nearly 90% of chiral compounds can be resolved at the analytical level using the polysaccharide-based CSPs. Although the qualitative understanding of the chiral recognition mechanism of polysaccharide-based CSPs is rather difficult in contrast to the small molecule-based CSPs, several attempts have made for comprehension of the chromatographic behavior on the polysaccharide-based CSPs. In this chapter, after describing the development of the polysaccharide-based CSPs with high recognition ability, special emphasis is placed on the mechanistic study of the polysaccharide-based CSPs on the basis of spectroscopic and computational methods. © 2010 Springer-Verlag Berlin Heidelberg.

Link information
DOI
https://doi.org/10.1007/978-3-642-12445-7_2
ID information
  • DOI : 10.1007/978-3-642-12445-7_2
  • SCOPUS ID : 84895236541

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