論文

国際誌
2021年3月20日

Associations between trunk-to-peripheral fat ratio and cardiometabolic risk factors in elderly Japanese men: baseline data from the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study.

Environmental health and preventive medicine
  • Katsuyasu Kouda
  • ,
  • Yuki Fujita
  • ,
  • Kumiko Ohara
  • ,
  • Takahiro Tachiki
  • ,
  • Junko Tamaki
  • ,
  • Akiko Yura
  • ,
  • Jong-Seong Moon
  • ,
  • Etsuko Kajita
  • ,
  • Kazuhiro Uenishi
  • ,
  • Masayuki Iki

26
1
開始ページ
35
終了ページ
35
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1186/s12199-021-00959-9

BACKGROUND: Body mass-independent parameters might be more appropriate for assessing cardiometabolic abnormalities than weight-dependent indices in Asians who have relatively high visceral adiposity but low body fat. Dual-energy X-ray absorptiometry (DXA)-measured trunk-to-peripheral fat ratio is one such body mass-independent index. However, there are no reports on relationships between DXA-measured regional fat ratio and cardiometabolic risk factors targeting elderly Asian men. METHODS: We analyzed cross-sectional data of 597 elderly men who participated in the baseline survey of the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) study, a community-based single-center prospective cohort study conducted in Japan. Whole-body fat and regional fat were measured with a DXA scanner. Trunk-to-appendicular fat ratio (TAR) was calculated as trunk fat divided by appendicular fat (sum of arm and leg fat), and trunk-to-leg fat ratio (TLR) as trunk fat divided by leg fat. RESULTS: Both TAR and TLR in the group of men who used ≥ 1 medication for hypertension, dyslipidemia, or diabetes ("user group"; N = 347) were significantly larger than those who did not use such medication ("non-user group"; N = 250) (P < 0.05). After adjusting for potential confounding factors including whole-body fat, both TAR and TLR were significantly associated with low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglyceride, fasting serum insulin, and the insulin resistance index in the non-user group and non-overweight men in the non-user group (N = 199). CONCLUSION: The trunk-to-peripheral fat ratio was associated with cardiometabolic risk factors independently of whole-body fat mass. Parameters of the fat ratio may be useful for assessing cardiometabolic risk factors, particularly in underweight to normal-weight populations.

リンク情報
DOI
https://doi.org/10.1186/s12199-021-00959-9
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33743595
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980554
ID情報
  • DOI : 10.1186/s12199-021-00959-9
  • PubMed ID : 33743595
  • PubMed Central 記事ID : PMC7980554

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