宮崎育子 (Ikuko Miyazaki) - マイポータル

基本情報

所属: 岡山大学医歯薬学総合研究科講師

学位: 博士（医学）(岡山大学)

J-GLOBAL ID: 200901005274978287
researchmap会員ID: 1000363194

外部リンク: http://www.okayama-u.ac.jp/user/mnb

研究キーワード

研究分野

経歴

学歴

1993年 - 1997年

岡山大学, 薬学部, 製薬化学科

委員歴

2023年6月 - 現在

日本毒性学会, 評議員
2021年 - 現在

日本毒性学会生体金属部会, 幹事
2020年7月 - 現在

日本パーキンソン病・運動障害疾患学会（MDSJ）, 評議員
2018年 - 現在

神経行動薬理若手研究者の集い, 世話人
2016年11月 - 現在

日本神経精神薬理学会, 広報委員
2015年 - 現在

日本神経精神薬理学会, 評議員
2014年 - 現在

日本薬理学会, 評議員

受賞

主要な論文

153

Rotenone targets midbrain astrocytes to produce glial dysfunction-mediated dopaminergic neurodegeneration

Ikuko Miyazaki, Nami Isooka, Ryo Kikuoka, Fuminori Imafuku, Kaori Masai, Kana Tomimoto, Masakiyo Sakaguchi, Chiharu Sogawa, Norio Sogawa, Yoshihisa Kitamura …

13(1) 234 2025年11月14日査読有り筆頭著者責任著者
An Endocrine-Disrupting Chemical, Bisphenol A Diglycidyl Ether (BADGE), Accelerates Neuritogenesis and Outgrowth of Cortical Neurons via the G-Protein-Coupled Estrogen Receptor

Ikuko Miyazaki, Chiharu Nishiyama, Takeru Nagoshi, Akane Miyako, Suzuka Ono, Ichika Misawa, Aika Isse, Kana Tomimoto, Kaori Masai, Kazumasa Zensho …

NeuroSci 6(2) 53-53 2025年6月6日査読有り筆頭著者責任著者
Multifunctional Metallothioneins as a Target for Neuroprotection in Parkinson’s Disease

Ikuko Miyazaki, Masato Asanuma

Antioxidants 12(4) 894-894 2023年4月6日査読有り招待有り筆頭著者責任著者
Neuron-Astrocyte Interactions in Parkinson’s Disease

Ikuko Miyazaki, Masato Asanuma

Cells 9(12) 2623-2623 2020年12月7日査読有り招待有り筆頭著者責任著者
Mirtazapine exerts astrocyte-mediated dopaminergic neuroprotection

Ryo Kikuoka, Ikuko Miyazaki, Natsuki Kubota, Megumi Maeda, Daiki Kagawa, Masaaki Moriyama, Asuka Sato, Shinki Murakami, Yoshihisa Kitamura, Toshiaki Sendo …

Scientific Reports 10(1) 20698-20698 2020年12月査読有り
The Rotenone Models Reproducing Central and Peripheral Features of Parkinson’s Disease

Ikuko Miyazaki, Masato Asanuma

NeuroSci 1(1) 1-14 2020年8月5日査読有り招待有り筆頭著者責任著者
Chronic Systemic Exposure to Low-Dose Rotenone Induced Central and Peripheral Neuropathology and Motor Deficits in Mice: Reproducible Animal Model of Parkinson’s Disease

Ikuko Miyazaki, Nami Isooka, Fuminori Imafuku, Jin Sun, Ryo Kikuoka, Chieko Furukawa, Masato Asanuma

International Journal of Molecular Sciences 21(9) 3254-3254 2020年5月4日査読有り招待有り筆頭著者責任著者
Effects of maternal bisphenol A diglycidyl ether exposure during gestation and lactation on behavior and brain development of the offspring

Ikuko Miyazaki, Ryo Kikuoka, Nami Isooka, Mika Takeshima, Kanau Sonobe, Rei Arai, Hidemaru Funakoshi, Kyle E. Quin, Jonathan Smart, Kazumasa Zensho …

Food and Chemical Toxicology 138 111235-111235 2020年4月査読有り筆頭著者責任著者
Dopaminergic neuroprotective effects of rotigotine via 5-HT1A receptors: Possibly involvement of metallothionein expression in astrocytes

Nami Isooka, Ikuko Miyazaki, Ryo Kikuoka, Kouichi Wada, Erika Nakayama, Kotaro Shin, Daichi Yamamoto, Yoshihisa Kitamura, Masato Asanuma

Neurochemistry International 132 104608-104608 2020年1月査読有り
Effects of Enteric Environmental Modification by Coffee Components on Neurodegeneration in Rotenone-Treated Mice

Ikuko Miyazaki, Nami Isooka, Kouichi Wada, Ryo Kikuoka, Yoshihisa Kitamura, Masato Asanuma

Cells 8(3) 221-221 2019年3月7日査読有り招待有り筆頭著者責任著者
Region-Specific Neuroprotective Features of Astrocytes against Oxidative Stress Induced by 6-Hydroxydopamine

Masato Asanuma, Nao Okumura-Torigoe, Ikuko Miyazaki, Shinki Murakami, Yoshihisa Kitamura, Toshiaki Sendo

International Journal of Molecular Sciences 20(3) 598-598 2019年1月30日査読有り招待有り
Therapeutic Strategy of Targeting Astrocytes for Neuroprotection in Parkinson's Disease

Ikuko Miyazaki, Masato Asanuma

Current Pharmaceutical Design 23(33) 2018年1月10日査読有り招待有り筆頭著者責任著者
Editorial: Astrocyte-targeted therapeutic strategies for neurological disorders.

Ikuko Miyazaki

Current Pharmaceutical Design 23(33) 4933-4935 2017年査読有り招待有り筆頭著者責任著者
Serotonin-1A agonist 8-OH-DPAT alleviates motor dysfunction and motor neuron degeneration in a model of amyotrophic lateral sclerosis.

Ikuko Miyazaki, Shinki Murakami, Takashi Nakano, Nao Torigoe, Ryo Kikuoka, Yoshihisa Kitamura, Toshiaki Sendo, Masato Asanuma

Annals of Pharmacology and Pharmaceutics 1(1) 1003-1003 2016年査読有り招待有り筆頭著者責任著者
Serotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson's Disease

Ikuko Miyazaki, Masato Asanuma

CURRENT MEDICINAL CHEMISTRY 23(7) 686-700 2016年査読有り筆頭著者責任著者
Neuroprotective effects of levetiracetam target xCT in astrocytes in parkinsonian mice

Ikuko Miyazaki, Shinki Murakami, Nao Torigoe, Yoshihisa Kitamura, Masato Asanuma

JOURNAL OF NEUROCHEMISTRY 136(1) 194-204 2016年1月査読有り筆頭著者
Targeting 5-HT1A receptors in astrocytes to protect dopaminergic neurons in parkinsonian models

Ikuko Miyazaki, Masato Asanuma, Shinki Murakami, Mika Takeshima, Nao Torigoe, Yoshihisa Kitamura, Ko Miyoshi

Neurobiology of Disease 59(59) 244-256 2013年11月査読有り筆頭著者
Astrocyte-Derived Metallothionein Protects Dopaminergic Neurons from Dopamine Quinone Toxicity

Ikuko Miyazaki, Masato Asanuma, Yuri Kikkawa, Mika Takeshima, Shinki Murakami, Ko Miyoshi, Norio Sogawa, Taizo Kita

GLIA 59(3) 435-451 2011年3月査読有り筆頭著者
Neuroprotective Effects of Zonisamide Target Astrocyte

Masato Asanuma, Ikuko Miyazaki, Francisco J. Diaz-Corrales, Naotaka Kimoto, Yuri Kikkawa, Mika Takeshima, Ko Miyoshi, Miho Murata

ANNALS OF NEUROLOGY 67(2) 239-249 2010年2月査読有り
Approaches to Prevent Dopamine Quinone-Induced Neurotoxicity

Ikuko Miyazaki, Masato Asanuma

NEUROCHEMICAL RESEARCH 34(4) 698-706 2009年4月査読有り筆頭著者責任著者
Dopaminergic neuron-specific oxidative stress caused by dopamine itself

Ikuko Miyazaki, Masato Asanuma

ACTA MEDICA OKAYAMA 62(3) 141-150 2008年6月筆頭著者責任著者
Protective effects of metallothionein against dopamine quinone-induced dopaminergic neurotoxicity

Ikuko Miyazaki, Masato Asanuma, Hiroaki Hozumi, Ko Miyoshi, Norio Sogawa

FEBS LETTERS 581(25) 5003-5008 2007年10月査読有り筆頭著者
Methamphetamine‐induced dopaminergic neurotoxicity is regulated by quinone formation‐related molecules

Ikuko Miyazaki, Masato Asanuma, Francisco J. Diaz‐Corrales, Masaya Fukuda, Kiyoyuki Kitaichi, Ko Miyoshi, Norio Ogawa

The FASEB Journal 20(3) 571-573 2006年3月査読有り筆頭著者
Dopamine agonist pergolide prevents levodopa-induced quinoprotein formation in Parkinsonian striatum and shows quenching effects on dopamine-semiquinone generated in vitro

Ikuko Miyazaki, Masato Asanuma, Francisco J. Diaz-Corrales, Ko Miyoshi, Norio Ogawa

Clinical Neuropharmacology 28(4) 155-160 2005年7月査読有り
Direct evidence for expression of dopamine receptors in astrocytes from basal ganglia

Ikuko Miyazaki, Masato Asanuma, Francisco J. Diaz-Corrales, Ko Miyoshi, Norio Ogawa

Brain Research 1029(1) 120-123 2004年12月10日査読有り筆頭著者
Age-related changes in expression of metallothionein-III in rat brain

Ikuko Miyazaki, Masato Asanuma, Youichirou Higashi, Chiharu Aoki Sogawa, Ken-ichi Tanaka, Norio Ogawa

Neuroscience Research 43(4) 323-333 2002年8月査読有り筆頭著者
Expression of metallothionein-III mRNA and its regulation by levodopa in the basal ganglia of hemi-parkinsonian rats

Ikuko Miyazaki, Chiharu Aoki Sogawa, Masato Asanuma, Youichirou Higashi, Ken-ichi Tanaka, Tohru Nakanishi, Norio Ogawa

Neuroscience Letters 293(1) 65-68 2000年10月査読有り筆頭著者
Bifemelane hydrochloride protects against cytotoxicity of hydrogen peroxide on cultured rat neuroblastoma cell line

Ikuko Miyazaki, Emi Iwata-Ichikawa, Masato Asanuma, Motoyuki Iida, Norio Ogawa

Neurochemical Research 24(7) 857-860 1999年査読有り筆頭著者