Takenori Inomata

J-GLOBAL         Last updated: Sep 23, 2018 at 10:37
 
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Name
Takenori Inomata
Research funding number
10645667
Twitter ID
eyetake
ORCID ID
0000-0003-3435-1055

Research Areas

 
 
  • Basic medicine / Immunology / Cornea Transplantation Immunology
  • Basic medicine / Immunology / dry eye disease
  • Clinical surgery / Ophthalmology / Cytomegalovirus Corneal Endothelitiis
  • Clinical surgery / Ophthalmology / Perlecan
  • Basic medicine / Immunology / Regulatory T cell

Academic & Professional Experience

 
Nov 2015
 - 
Today
Assistant Profesor, Department of Ophthalmology, Juntendo University School of Medicine
 
Sep 2012
 - 
Oct 2015
Postdoctoral Fellow, Department of Ophthalmology, Schepens Eye Research institute, Harvard Medical School
 
Apr 2012
 - 
Aug 2012
Assistant Professor, Department of Ophthalmology, Juntendo University School of Medicine
 
Apr 2006
 - 
Mar 2008
Residency, Residency, The University of Tokyo Hospital
 

Education

 
Sep 2012
 - 
Sep 2015
Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School
 
Dec 2013
 - 
Jun 2015
Master of Business Administration, School of Management, Boston University
 
Apr 2008
 - 
Mar 2012
Ophthalmology, Medicine, Juntendo University Graduate School
 
Apr 2000
 - 
Mar 2006
School of Medicine, Juntendo University
 

Awards & Honors

 
Nov 2017
Relationship between dry eye subjective symptoms and lifestyle habits: Large-scale clinical research using iPhone application, the KOS Travel Grant, the Korean Ophthalmological Society.
Winner: Takenori Inomata, Masahiro Nakamura, Yusuke Yoshimura, Masao Iwagami, Yoshimune Horastuka, Satoshi Hori, Keiichi Fujimoto, Yuichi Okumura, Tina Shiang, Akira Murakami
 
Oct 2017
The 30th Biennial Cornea Conference Travel Award, The 30th Biennial Cornea Conference
Winner: Osama Hirayama, Keiichi Fujimoto, Takenori Inomata, Koichiro Uchida, Tina Shiang, Akira Murakami
 
Jul 2016
TFOS Travel Awards 2016, TFOS Travel Awards 2016, Tear Film & Ocular Surface Society
 
May 2015
Blood and lymphatic vessels in the cornea after transplantation, 29th Biennial Cornea Conference Cover Picture Contest, Harvard Medical School, Department of Ophthalmology
 
Feb 2015
Regulatory T Cell Dysfunction in High-Risk Corneal Transplantation, Travel Grant for Asia-ARVO 2015 meeting, The Association for Research in Vision and Ophthalmology
 
Oct 2014
Alumni Scholarship,Juntendo University School of Medicine, Juntendo University School of Medicine Alumni Association
 
Jan 2014
Boston University Executive MBA Scholarship, Boston University School of Management
 
May 2012
Association for Research in Vision and Ophthalmology (ARVO) KOWA Travel Grants, Association for Research in Vision and Ophthalmology & KOWA
 
Dec 2011
MEEI/BLJ ocular surface research fellowship
 

Published Papers

 
Inomata T, Iwagami M, Hiratsuka Y, Fujimoto K, Okumura Y, Shiang T, Murakami A
Scientific reports   8(1) 13443   Sep 2018   [Refereed]
Tan X, Chen Y, Foulsham W, Amouzegar A, Inomata T, Liu Y, Chauhan SK, Dana R
The ocular surface      Jul 2018   [Refereed]
Hua J, Inomata T, Chen Y, Foulsham W, Stevenson W, Shiang T, Bluestone JA, Dana R
Scientific reports   8(1) 7059   May 2018   [Refereed]
Takei M, Obana A, Inomata T, Tanaka T, Shiang T, Bae Y, Takemura T, Murakami A
BMC ophthalmology   18(1) 72   Mar 2018   [Refereed]
Inomata T, Shiang T, Iwagami M, Sakemi F, Fujimoto K, Okumura Y, Ohno M, Murakami A
Scientific reports   8(1) 1918   Jan 2018   [Refereed]
Inomata T, Mizuno J, Iwagami M, Kawasaki S, Shimada A, Inada E, Shiang T, Amano A
PloS one   13(9) e0204301   2018   [Refereed]
Inomata T, Hua J, Nakao T, Shiang T, Chiang H, Amouzegar A, Dana R
Cornea      Oct 2017   [Refereed]
Chen Y, Chauhan SK, Shao C, Omoto M, Inomata T, Dana R
Journal of immunology (Baltimore, Md. : 1950)      Jun 2017   [Refereed]
Inomata T, Ono K, Matsuba T, Shiang T, Di Zazzo A, Nakatani S, Yamaguchi M, Ebihara N, Murakami A
Japanese journal of ophthalmology      Jun 2017   [Refereed]
A New Immunotherapy Using Regulatory T-Cells for High-Risk Corneal Transplantation
Takenori Inomata
Juntendo Medical Journal   63(1) 2-7   Apr 2017   [Refereed][Invited]

Misc

 
New Large-Scale Dry Eye Research by iPhone "Dry Eye Rhythm" Application Using ResearchKit
Takenori Inomata
Journal of the Ryr   35(7) 871-877   Jul 2018   [Invited]
Comparison of Concepts of Dry Eye Disease around the world
Takenori Inomata
Journal of the Eye   34(3) 371-380   Mar 2017   [Invited]

Conference Activities & Talks

 
Cut–Off Value of DEQS for Diagnosing Dry Eye Disease
Yuichi Okumura, Takenori Inomata, Keiichi Fujimoto, Tina Shiang, Masao Iwagami, Yoshimune Hiratsuka, and Akira Murakami.
World Ophthalmology Congress 2018   18 Jun 2018   
Maximum blink interval correlated with tear break-up time is a useful indicator for dry eye disease
Takenori Inomata, Tina Shiang, Masao Iwagami, , Keiichi Fujimoto, Yuichi Okumura, Yoshimune Hirastuka and Akira Murakami
World Ophthalmology Congress 2018   16 Jun 2018   
Higher Corneal Allograft Rejection Rates in the Very Young Are Associated with Heightened NK cell Response in the Setting of Regulatory T cell Dysfunction
Takeshi Nakao, Takenori Inomata, Maryam Tahvildari, Afsaneh Amouzegar, Reza Dana
ARVO 2018 Annual Meeting   1 May 2018   
Rho-Kinase Inhibitor Ripasudil suppresses dendritic cell maturation in murine corneal transplantation
Maria Karasawa, Takenori Inomata, Mikiko Okano, Keiichi Fujimoto, Yuichi Okumura, Tina Shiang, Toshinari Funaki, Akira Murakami
ARVO 2018 Annual Meeting   1 May 2018   
The effect of Anti-CD80/86 antibody on regulatory T cells in murine corneal transplantation
Keiichi Fujimoto, Takenori Inomata, Koichiro Uchida, Tina Shiang, Yuichi Okumura, Akira Murakami
ARVO 2018 Annual Meeting   1 May 2018   
Relationship between subjective symptoms of dry eye disease and lifestyle habits: Large-scale clinical research using iPhone application
Takenori Inomata, Masahiro Nakamura, Yusuke Yoshimura, Masao Iwagami, Yoshimune Hirastuka, Satoshi Hori, Keiichi Fujimoto, Yuichi Okumura, Tina Shiang, Akira Murakami
ARVO 2018 Annual Meeting   29 Apr 2018   
Maximum blink interval : A new simple, screening test for dry eye disease
Takenori Inomata、Masao Iwagami、Tina Shiang、Keiichi Fujimoto、 Yuichi Okumura、Yoshimune Hiratsuka、Akira Murakami
17 Feb 2018   
A New Immunotherapy using Regulatory T Cells for High-Risk Corneal Transplantation [Invited]
Takenori Inomata
15 Feb 2018   
Evaluation of DEQS to identify dry eye disease and its severity by ROC analysis
Yuichi Okumura, Takenori Inomata, Tina Shiang, Masao Iwagami, Keiichi Fujimoto, and Akira Murakami
15 Feb 2018   
Comparison of the utility of DEQS and OSDI for dry eye disease on the new diagnostic criteria
Hasegawa H, Inomata T, Iwanami M, Fujimoto K, Okumura Y, Shiang T, Murakami A
15 Feb 2018   
The immunological effects of Anti-CD80/86 injection on murine corneal transplantation
Keiichi Fujimoto, Takenori Inomata, Koichiro Uchida, Tina Shiang, Akira Murakami
15 Feb 2018   
The impact of the standardization of operating room protocols set forth by the Joint Commission International on operating room time periods in phacoemulsification and aspiration with intraocular lens implantation.
Atsuko Eguchi, Yuichi Okumura, Takenori Inomata, Ju Mizuno, Atsushi Amano, and Akira Murakami
The 33rd Asia-Pacific Academy of Ophthalmology   11 Feb 2018   
Evaluation of DEQS to identify corneal and conjunctival epithelial damage by ROC analysis
Yuichi Okumura, Takenori Inomata, Masao Iwagami, Keiichi Fujimoto, Tina Shiang and Akira Murakami
The 33rd Asia-Pacific Academy of Ophthalmology   10 Feb 2018   
Changes in Distribution of Dry Eye Disease
Takenori Inomata. Tina Shiang, Masao Iwagami, Fumika Sakemi, Keiichi Fujimoto, Yuichi Okumura, Mizu Ohno, and Akira Murakami
The 33rd Asia-Pacific Academy of Ophthalmology   10 Feb 2018   
Relationship between dry eye subjective symptoms and lifestyle habits: Large-scale clinical research using iPhone application
Takenori Inomata,Masahiro Nakamura、Yusuke Yohimura, Masao Iwagami, Yoshimune Hiratsuka, Satoshi Hori, Keiichi Fujimoto, Yuichi Okumura, Tina Shiang and Akira Murakami
The Korea Ophthalmology Society   3 Nov 2017   
Anti-CD80/86 injection prolongs the graft survival in murine corneal transplantation
Keiichi Fujimoto, Takenori Inomata, Koichiro Uchida, Tina Shiang, Akira Murakami
14th International Ocular Inflammation Society Meeting   18 Oct 2017   
Utility of smartphone application in assessing dry eye disease
Yuichi Okumura, Takenori Inomata, Masahiro Nakamura, Yusuke Yoshimura, Yoshimune Hiratsuka, Tina Shiang and Akira Murakami
14th International Ocular Inflammation Society Meeting   18 Oct 2017   
Anti-Bacterial Effects on Ocular Surface Pathology in Dry Eye Disease
Takenori Inomata, Lang Bai, Tina Shiang, Gerald Pier and Jing Hua
14th International Ocular Inflammation Society Meeting   18 Oct 2017   
Anti-CD80/86 injection prolongs the graft survival in murine corneal transplantation
Osama Hirayama, Keiichi Fujimoto, Takenori Inomata, Koichiro Uchida, Tina Shiang, Akira Murakami
30th Biennial Cornea Conference   12 Oct 2017   
Utility of smartphone application in assessing dry eye disease [Invited]
Takenori Inomata
The 15th Annual Meeting of Japanese Society of Hospital General Medicine   15 Sep 2017   
Interferon gamma-Positive Natural Killer Cells Contribute to Corneal Allograft Rejection in Young Mice
Takeshi Nakao; Takenori Inomata; Maryam Tahvildari; Reza Dana
ARVO2017   May 2017   
ARVO Annual Meeting Abstract June 2017 Potential Role of IL-10-producing Th17 Cells in Pathogenesis of Dry Eye Disease
Qi Hong; Yihe Chen; Takenori Inomata; Rongjun Liu; Reza Dana
ARVO2017   May 2017   
Analysis of serum trace elements in age-related macular degeneration
The 121st Annual Meeting of the Japanese Ophthalmology Society   8 Apr 2017   
Utility of smartphone application in assessing DED
Yuichi Okumura, Takenori Inomata, Masahiro Nakamura, Yusuke Yoshimura, Yoshimune Hiratsuka, Akira Murakami
The 121st Annual Meeting of the Japanese Ophthalmology Society   7 Apr 2017   
Anti-Bacterial Effects on Ocular Surface Immunology in Dry Eye Disease
Takenori Inomata, Lang Bai, Tina Shiang, Gerald Pier, Jing Hua
The 121st Annual Meeting of the Japanese Ophthalmology Society   6 Apr 2017   
The Effects of ROCK inhibitor K-115 (Ripasudil) on Murine Corneal Transplantation
Takenori Inomata, Kimiko Okano, Toshinari Funaki, Tina Shiang, Akira Murakami
32nd Asia-Pacific Academy of Ophthalmology Congress 2017   1 Mar 2017   
Sjögren' syndrome Deviate their Subjective Symptoms and Corneal Epithelial Disorder
Yuichi Okumura, Takenori Inomata, Tina Shiang, Yoshimune Hiratsuka and Akira Murakami
The 5th Asia Cornea Society Biennial Scientific Meeting   8 Dec 2016   
The effects of ROCK inhibitor K-115 (Ripasudil) on graft survival in murine corneal transplantation [Invited]
Takenori Inomata, Mikiko Okano, Toshinari Funaki, Tina Shiang, Akira Murakami
The 5th Asia Cornea Society Biennial Scientific Meeting   8 Dec 2016   
The Prevalence of Methicillin-Resistant Staphylococcus in Preservation Medium for Penetrating Keratoplasty.
Takenori Inomata
The 70th Annual Congress of Japan Clinical Ophthalmology   4 Nov 2016   
CHANGES IN CORNEAL ENDOTHELIAL MORPHOLOGY AND CORNEAL THICKNESS IN PATIENTS WITH DRY EYE DISEASE AND SJÖGREN’S SYNDROME
Mizu Ono, Takenori Inomata, Yoshimune Hiratsuka, Tina Shiang, Akira Murakami.
Tear Film & Ocular Surface Society (TFOS) 2016    10 Sep 2016   
IMPAIRED FUNCTION OF PERIPHERALLY INDUCED REGULATORY T CELLS IN HOSTS OF HIGH RISK OF GRAFT REJECTION
Takenori Inomata, Jing Hua, Antonio Di Zazzo,and Reza Dana
Tear Film & Ocular Surface Society (TFOS) 2016    10 Sep 2016   
Pre-banking Microbial Assessment of Donor Conjunctiva and Storage Medium for Penetrating Keratoplasty
Maria Karasawa, Takenori Inomata, Akira Murakami
APACRS 2016   28 Jul 2016   
Does Dry Eye Disease Change Corneal Endothelial Morphology and Corneal Thickness?
Takenori Inomata, Yoshimune Hiratsuka, Sari Miyaji, Tina Shiang and Akira Murakami
APACRS 2016   28 Jul 2016   
Substance P suppresses Foxp3 expression in regulatory T cells in dry eye disease
Anna Marmalidou, Alireza MAshaghi-Tabari, Takenori Inomata, Yihe Chen, Sunil Chauhan, Reza Dana
FOCiS 2016   22 Jun 2016   
Kinetics of Angiogenic Responses in High-Risk Corneal Transplantation
Takenori Inomata, Alireza Mashaghi, Antonio Di Zazzo, Sang-Mok Lee, Chiang Homer and Reza Dana
16th Scientific Meeting of the Japanese Society of Anti-Aging Medicine   10 Jun 2016   
Pathological Conversion of Regulatory T Cells Cause Disruption of Immune Privilege
Jing Hua, Takenori Inomata, William Stevenson, Tina Shiang, Yihe Chen, Jeffrey Bluestone, Reza Dana
ARVO 2016   4 May 2016   
Corneal Transplant Survival in Young Mice
Takeshi Nakao, Takenori Inomata, Maryam Tahvildari, Reza Dana
ARV)2016   2 May 2016   
Is Dry Eye Disease in Donors a Risk Factor for Corneal Graft Rejection?
Takenori Inomata, Jing Hua, Tina Shiang, Homer Chiang, and Reza Dana.
ARVO2016   2 May 2016   
Substance P suppresses Foxp3 expression in regulatory T cells in dry eye disease
Anna Marmalidou, Alireza MAshaghi-Tabari, Takenori Inomata, Yihe Chen, Sunil Chauhan, Reza Dana
ARVO 2016   1 May 2016   
Corneal Tissue from Dry Eye Donors Leads to Enhanced Graft Rejection
Takenori Inomata, Jing Hua, Reza Dana
The 120th Annual Meeting of the Japanese Ophthalmological Society   8 Apr 2016   
Think future medical care [Invited]
Takenori Inomata
iSeminar   2 Apr 2016   
Corneal Grafts Prone to Reject Exhibit Impaired Function of Peripherally Induced Regulatory T Cells
Takenori Inomata, Jing Hua, Reza Dana
Japan Cornea Conference 2016   Feb 2016   
Corneal Grafts Prone to Rejection Exhibit Impaired Function of Peripherally Induced Regulatory T Cells [Invited]
Takenori Inomata
Harvard Medical School, Department Ophthalmology, Basic Science Research Fellows’ Recognition Day   3 Jun 2015   
Corneal Grafts Prone to Rejection Exhibit Impaired Function of Peripherally Induced Regulatory T Cells
Corneal Grafts Prone to Rejection Exhibit Impaired Function of Peripherally Induced Regulatory T Cells
Harvard Medical School Department of Ophthalmology Annual Meeting and Alumni Reunion   29 May 2015   
Desiccating Stress-induced Dry Eye Disease is a High-Risk Factor for Corneal Allograft Rejection
Jing Hua, Takenori Inomata, Tina Shiang, William Stevenson, Thomas H. Dohlman, Luk Vandenberghe, Masahiro Omoto, Susanne Eiglmeier, Qiang Zhang, Reza Dana
ARVO   6 May 2015   
The contribution of T cells to corneal angiogenic privilege in transplantation
Antonio Di Zazzo, Brinda Subbarayal, Thomas H. Dohlman, Takenori Inomata, Sunil Chauhan, Reza Dana
ARVO2015   6 May 2015   
Corneal Grafts Proned to Rejection Exhibit Impaired Function of Peripherally Induced Regulatory T Cells
Takenori Inomata, Jing Hua, Antonio Di Zazzo, Sang-Mok Lee, Homer Chang, Tina Shiang, Qiang Zhang, and Reza Dana
ARVO2015   6 May 2015   
Peripheral Induced Regulatory T Cells Dysfunction in High-Risk Corneal Transplantation
Takenori Inomata, Jing Hua, Sang-Mok Lee, Homer Chang, Tina Shiang, Qiang Zhang, and Reza Dana
World Cornea Congress Ⅶ   15 Apr 2015   
Disrupted Induction Of Induced Regulatory T Cells In The Dry Eye Host Exacerbates Corneal Allograft Rejection.
Jing Hua, William Stevenson, Yihe Chen, Thomas Dohlman, Takenori Inomata, Hyun Soo Lee, Sunil Chauhan, Reza Dana
Tear Film & Ocular Surface Society   Sep 2013   
Regulatory T Cell dysfunction in High-Risk Corneal Transplantation
Inomata T, Hua J, Lee SM, Shiang T, Chang H, Zhang Q, Dana R
Asia-ARVO 2015 meeting   19 Feb 2015   

Social Contribution

 
JGMS Seminar
[Lecturer, Organizing Member]  JGMS  21 Feb 2015
Massachusetts General Hospital Japanese Association
[Planner, Organizing Member]  Massachusetts General Hospital Japanese Association  Jul 2014
Harvard Visiting Tour for Japanese high school students
[Lecturer]  May 2014
MBA Beyond Asian Network
[Planner, Organizing Member]  Beyond Asian Network  Apr 2014
Harvard Lab Tour
[Lecturer, Planner, Organizing Member]  Mar 2014
[TV or radio appearance, Presenter, Lecturer, Informant, Planner, Organizing Member, Contribution]  Japan-Gobal Medical Career Support  Jan 2014 - Apr 2015
Juntendo Boston Community
[Planner, Organizing Member]  Jan 2014
Science Explores Group (SEG) program
[TV or radio appearance, Organizing Member, Demonstrator]  Leave a Nest  Mar 2013
Tokyo New Cinema
[Organizing Member]  Mar 2013
Young Ophthalmologist Updating Seminar (YOUS)
[Lecturer, Planner, Organizing Member]  Young Ophthalmologist Updating Seminar (YOUS)  Aug 2012