論文

査読有り
2018年5月15日

Synchronous Occurrence of Mycosis Fungoides, Diffuse Large B Cell Lymphoma and Acute Myeloid Leukemia.

Internal medicine (Tokyo, Japan)
  • Junichi Miyatake
  • ,
  • Hiroaki Inoue
  • ,
  • Kentarou Serizawa
  • ,
  • Yasuyoshi Morita
  • ,
  • J L Espinoza
  • ,
  • Hirokazu Tanaka
  • ,
  • Takahiro Shimada
  • ,
  • Yoichi Tatsumi
  • ,
  • Takashi Ashida
  • ,
  • Itaru Matsumura

57
10
開始ページ
1445
終了ページ
1453
記述言語
英語
掲載種別
DOI
10.2169/internalmedicine.9668-17

Patients with mycosis fungoides (MF), the most common subtype of primary cutaneous T-cell lymphoma, have an increased risk of developing secondary malignancies. We herein report two rare cases of MF concurring with diffuse large B cell lymphoma (B lymphoid lineage) and acute myeloid leukemia (myeloid lineage) in two otherwise healthy elderly patients. Potential etiologic factors, including the impact of the therapy-associated inflammatory response on the development of secondary tumors in patients with MF, are discussed. Further clinical, experimental and genetic studies are needed to elucidate possible physiopathogenic associations among the three concurrent malignancies occurring in the cases presented here.

リンク情報
DOI
https://doi.org/10.2169/internalmedicine.9668-17
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29321428
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995719

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