論文

査読有り
2005年8月15日

Selective detection of a catecholamine against electroactive interferents using an interdigitated heteroarray electrode consisting of a metal oxide electrode and a metal band electrode

Analytical Chemistry
  • Katsuyoshi Hayashi
  • ,
  • Yuzuru Iwasaki
  • ,
  • Tsutomu Horiuchi
  • ,
  • Kenji Sunagawa
  • ,
  • Akiyuki Tate

77
16
開始ページ
5236
終了ページ
5242
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1021/ac050216p

We developed an interdigitated array electrode (IDAE) consisting of a metal oxide electrode and a metal band heteroelectrode and employed it for the selective detection of catecholamines. We used an indium-tin oxide (ITO) film as the oxidation electrode of the IDAE because the ITO was able to suppress response currents from L-ascorbic acid (AA) and uric acid (UA), which are major electroactive interferents in biological fluids. However, the ITO film also suppresses the reduction of quinones including oxidized catecholamines. We developed a simple technique for fabricating our hetero IDAE, which also preserves the electrochemical properties of the ITO. When we compared hetero ITO-gold, homo ITO-ITO, and carbon-carbon IDAEs, we found that the hetero IDAE provided both high sensitivity and selectivity for DA detection. We achieved high selectivities for DA against AA and UA. The ratios of the response currents of AA and UA to DA were calculated as 6 and 5%, respectively. © 2005 American Chemical Society.

リンク情報
DOI
https://doi.org/10.1021/ac050216p
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/16097764
ID情報
  • DOI : 10.1021/ac050216p
  • ISSN : 0003-2700
  • PubMed ID : 16097764
  • SCOPUS ID : 23744502249

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