論文

査読有り 国際誌
2021年11月4日

Sugary drink consumption and risk of kidney and bladder cancer in Japanese adults.

Scientific reports
  • Chi Yan Leung
  • ,
  • Sarah Krull Abe
  • ,
  • Norie Sawada
  • ,
  • Junko Ishihara
  • ,
  • Ribeka Takachi
  • ,
  • Taiki Yamaji
  • ,
  • Motoki Iwasaki
  • ,
  • Masahiro Hashizume
  • ,
  • Manami Inoue
  • ,
  • Shoichiro Tsugane

11
1
開始ページ
21701
終了ページ
21701
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/s41598-021-01103-x

Globally, sugary drinks are widely consumed, however, few epidemiologic studies have investigated the association between sugary drink consumption and risk of kidney and bladder cancer. We examined the association of sugary drinks with risk of kidney and bladder cancer in 73,024 participants from the Japan Public Health Center-based Prospective Study who reported no history of cancer. Sugary drink consumption was assessed using a validated food frequency questionnaire at study baseline (1995-1999). Individuals were followed to December 31, 2013. Multivariable Cox proportional hazards regression models were used to calculate hazard ratios (HR) and 95% confidence intervals (CIs). During 1,069,815 person years of follow-up, 169 kidney cancer and 297 bladder cancer cases were documented. After adjusting for potential confounders, no greater risk of kidney and bladder cancer was observed. However, sugary drink consumption was positively associated with the risk of kidney cancer (HR for 100 ml/day increase in consumption was 1.11 [95% CI 1.01-1.22]) and bladder cancer (HR for 100 ml/d increase in consumption was 1.11 [95% CI 1.01-1.22]) among women after exclusion of cases diagnosed in the first three years of follow-up. In this large prospective cohort, consumption of sugary drinks was significantly associated with a small increase in hazard ratio for kidney and bladder cancer among women after exclusion of cases diagnosed within the first three years.

リンク情報
DOI
https://doi.org/10.1038/s41598-021-01103-x
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34737349
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568905
ID情報
  • DOI : 10.1038/s41598-021-01103-x
  • PubMed ID : 34737349
  • PubMed Central 記事ID : PMC8568905

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