遠藤仁 (Jin Endo) - マイポータル

基本情報

所属: 慶應義塾大学医学部（信濃町）専任講師

学位: 医学博士(慶應義塾大学)

J-GLOBAL ID: 201501054870848127
researchmap会員ID: B000243746

外部リンク: https://kaken.nii.ac.jp/d/r/50398608.ja.html

研究キーワード

研究分野

ライフサイエンス / 循環器内科学 /

経歴

論文

Clonal Hematopoiesis in Chronic Thromboembolic Pulmonary Hypertension

Mizuki Momoi, Yoshinori Katsumata, Hiroyoshi Kunimoto, Takumi Inami, Fuyuki Miya, Atsushi Anzai, Shinichi Goto, Ayaka Miura, Yoshiki Shinya, Takahiro Hiraide …

Journal of the American Heart Association 2024年11月27日
MRP1-Dependent Extracellular Release of Glutathione Induces Cardiomyocyte Ferroptosis After Ischemia-Reperfusion.

Genki Ichihara, Yoshinori Katsumata, Yuki Sugiura, Yuta Matsuoka, Rae Maeda, Jin Endo, Atsushi Anzai, Kohsuke Shirakawa, Hidenori Moriyama, Hiroki Kitakata …

Circulation research 133(10) 861-876 2023年10月11日
Genetic Testing Enables the Diagnosis of Familial Hypercholesterolemia Underdiagnosed by Clinical Criteria: Analysis of Japanese Early-Onset Coronary Artery Disease Patients

Hiroshi Miyama, Yoshinori Katsumata, Mizuki Momoi, Genki Ichihara, Taishi Fujisawa, Jin Endo, Takashi Kawakami, Masaharu Kataoka, Shinsuke Yuasa, Motoaki Sano …

Cardiology Research and Practice 2023 1-7 2023年4月28日
Pathophysiological Involvement of Mast Cells and the Lipid Mediators in Pulmonary Vascular Remodeling

Hidenori Moriyama, Jin Endo

International Journal of Molecular Sciences 2023年4月1日査読有り
Molecular Mechanism of Pathogenesis and Treatment Strategies for AL Amyloidosis.

Hidehiko Ikura, Jin Endo, Hiroki Kitakata, Hidenori Moriyama, Motoaki Sano, Keiichi Fukuda

International journal of molecular sciences 23(11) 2022年6月6日査読有り
Treatment of transthyretin His88Arg amyloidosis with RNA interference therapy: A case report.

Hiroki Kitakata, Hidenori Moriyama, Jin Endo, Hidehiko Ikura, Keiichi Fukuda, Motoaki Sano

Journal of cardiology cases 25(6) 363-366 2022年6月
Omega-3 fatty acid epoxides produced by PAF-AH2 in mast cells regulate pulmonary vascular remodeling.

Hidenori Moriyama, Jin Endo, Masaharu Kataoka, Yuta Shimanaka, Nozomu Kono, Yuki Sugiura, Shinichi Goto, Hiroki Kitakata, Takahiro Hiraide, Naohiro Yoshida …

Nature communications 13(1) 3013-3013 2022年5月31日
Three patients of transthyretin amyloidosis in a Japanese family with amyloidogenic transthyretin Thr49Ser (p.Thr69Ser) variant.

Hidehiko Ikura, Hiroki Kitakata, Jin Endo, Hidenori Moriyama, Motoaki Sano, Hanako Tsujikawa, Mitsuaki Sawano, Teruaki Masuda, Takahiro Ohki, Mitsuharu Ueda …

European journal of medical genetics 65(3) 104451-104451 2022年3月
Qualitative and Quantitative Effects of Fatty Acids Involved in Heart Diseases.

Hidenori Moriyama, Jin Endo, Hidehiko Ikura, Hiroki Kitakata, Mizuki Momoi, Yoshiki Shinya, Seien Ko, Genki Ichihara, Takahiro Hiraide, Kohsuke Shirakawa …

Metabolites 12(3) 2022年2月25日
Therapeutic Targets for DOX-Induced Cardiomyopathy: Role of Apoptosis vs. Ferroptosis.

Hiroki Kitakata, Jin Endo, Hidehiko Ikura, Hidenori Moriyama, Kohsuke Shirakawa, Yoshinori Katsumata, Motoaki Sano

International journal of molecular sciences 23(3) 2022年1月26日
Step-by-step typing for the accurate diagnosis of concurrent light chain and transthyretin cardiac amyloidosis.

Hidenori Moriyama, Hiroki Kitakata, Jin Endo, Hidehiko Ikura, Motoaki Sano, Masayoshi Tasaki, Shunta Sakai, Mitsuharu Ueda, Keiichi Fukuda

ESC heart failure 9(2) 1474-1477 2022年1月21日
Imeglimin prevents heart failure with preserved ejection fraction by recovering the impaired unfolded protein response in mice subjected to cardiometabolic stress.

Hiroki Kitakata, Jin Endo, Shun Hashimoto, Erika Mizuno, Hidenori Moriyama, Kohsuke Shirakawa, Shinichi Goto, Yoshinori Katsumata, Keiichi Fukuda, Motoaki Sano

Biochemical and biophysical research communications 572 185-190 2021年10月1日
Predictors of New-Onset Atrial Tachyarrhythmias After Transcatheter Atrial Septal Defect Closure in Adults.

Kotaro Miura, Mai Kimura, Atsushi Anzai, Takahide Arai, Takashi Kawakami, Shinsuke Yuasa, Kentaro Hayashida, Jin Endo, Hikaru Tsuruta, Yuji Itabashi …

Heart, lung & circulation 30(9) 1406-1413 2021年9月
MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis.

Hiroki Kitakata, Jin Endo, Hirokazu Matsushima, Shoichi Yamamoto, Hidehiko Ikura, Akeo Hirai, Seien Koh, Genki Ichihara, Takahiro Hiraide, Hidenori Moriyama …

Journal of molecular and cellular cardiology 161 116-129 2021年8月11日
Time-Series Transcriptome Analysis Reveals the miR-27a-5p-Ppm1l Axis as a New Pathway Regulating Macrophage Alternative Polarization After Myocardial Infarction.

Shinichi Goto, Genki Ichihara, Yoshinori Katsumata, Seien Ko, Atsushi Anzai, Kohsuke Shirakawa, Jin Endo, Masaharu Kataoka, Hidenori Moriyama, Takahiro Hiraide …

Circulation journal : official journal of the Japanese Circulation Society 85(6) 929-938 2021年5月25日
Artificial intelligence-enabled fully automated detection of cardiac amyloidosis using electrocardiograms and echocardiograms.

Shinichi Goto, Keitaro Mahara, Lauren Beussink-Nelson, Hidehiko Ikura, Yoshinori Katsumata, Jin Endo, Hanna K Gaggin, Sanjiv J Shah, Yuji Itabashi, Calum A MacRae …

Nature communications 12(1) 2726-2726 2021年5月11日
Appropriate device selection for transcatheter atrial septal defect closure using three-dimensional transesophageal echocardiography

Hiroki Kitakata, Yuji Itabashi, Hideaki Kanazawa, Kotaro Miura, Mai Kimura, Keitaro Shinada, Marjolein C. de Jongh, Jin Endo, Hikaru Tsuruta, Mitsushige Murata …

International Journal of Cardiovascular Imaging 37(4) 1159-1168 2021年4月1日
TNFRSF13B c.226G>A (p.Gly76Ser) as a Novel Causative Mutation for Pulmonary Arterial Hypertension.

Yoshiki Shinya, Takahiro Hiraide, Mizuki Momoi, Shinichi Goto, Hisato Suzuki, Yoshinori Katsumata, Yutaka Kurebayashi, Jin Endo, Motoaki Sano, Keiichi Fukuda …

Journal of the American Heart Association 10(5) e019245 2021年2月
Clinical Significance of Guanylate Cyclase Stimulator, Riociguat, on Right Ventricular Functional Improvement in Patients with Pulmonary Hypertension.

Mitsushige Murata, Takashi Kawakami, Masaharu Kataoka, Hidenori Moriyama, Takahiro Hiraide, Mai Kimura, Jin Endo, Takashi Kohno, Yuji Itabashi, Keiichi Fukuda

Cardiology 146(1) 130-136 2021年
Preoperative right ventricular strain predicts sustained right ventricular dysfunction after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension.

Toshimitsu Tsugu, Takashi Kawakami, Masaharu Kataoka, Jin Endo, Takashi Kohno, Yuji Itabashi, Keiichi Fukuda, Mitsushige Murata

Echocardiography (Mount Kisco, N.Y.) 37(12) 2040-2047 2020年12月

もっとみる

MISC

Cardiac Sirt1 Mediates the Cardioprotective Effect of Caloric Restriction by Suppressing Local Complement System Activation after Ischemia/Reperfusion

Tsunehisa Yamamoto, Ken Shinmura, Motoaki Sano, Jin Endo, Keiichi Fukuda

JOURNAL OF CARDIAC FAILURE 21(10) S147-S147 2015年10月
炎症細胞-線維芽細胞間におけるω-3脂肪酸代謝物を介した心臓リモデリング抑制機構

遠藤仁, 佐野元昭, 新井洋由, 福田恵一, 有田誠

日本循環制御医学会総会プログラム・抄録集 35回 118-118 2014年7月
メタボロミクスの食品・環境分野への新展開 ω3系脂肪酸の代謝と抗炎症作用のメタボローム解析

有田誠, 磯部洋輔, 遠藤仁, 新井洋由

日本薬学会年会要旨集 134年会(1) 264-264 2014年3月
Deleterious Effect of IL-23/IL-17A Axis and gamma delta T Cells in Left Ventricular Remodeling after Myocardial Infarction in Rodent

Xiaoxiang Yan, Takashi Shichita, Yoshinori Katsumata, Tomohiro Matsuhashi, Hideyuki Ito, Kentaro Ito, Atsushi Anzai, Jin Endo, Yuichi Tamura, Kensuke Kimura …

CIRCULATION 126(21) 2012年11月
Cooperative Operation of PGD(2)/FP and 15d-PGJ(2)/nrf2 Pathway in the L-PGDS-Mediated Cardioprotection

Yoshinori Katsumata, Motoaki Sano, Ken Shinmura, Tomohiro Matsuhashi, Shugo Tohyama, Jin Endo, Atsushi Anzai, Cardex Yan, Keiishi Fukuda

CIRCULATION 124(21) 2011年11月
ATF4-regulated Metabolic Shift Towards Phgdh-mediated Serine Synthesis Enhances Cardioprotection Against Oxidative Stress

Jin Endo, Takaharu Katayama, Motoaki Sano, Yoshinori Katsumata, Tomohiro Matsuhashi, Shinji Makino, Satoshi Ogawa, Keiichi Fukuda

CIRCULATION 120(18) S855-S855 2009年11月
Molecular Characterization, Safety and Feasibility of Induced Pluripotent Stem (iPS) Cell Derived Cardiomyocytes for Heart Regenerative Therapy

Yohei Ohno, Shinsuke Yuasa, Takeshi Onizuka, Toru Egashira, Kenichiro Shimoji, Sung Han Yoon, Takahide Arai, Jin Endo, Toshimi Kageyama, Hao Chan …

CIRCULATION 118(18) S429-S429 2008年10月
DEXAMETHASONE INDUCES LATE PHASE OF CARDIOPROTECTION VIA A CYCLOOXYGENASE-2-DEPENDENT MECHANISM

Kayoko Tamaki, Ken Shinmura, Motoaki Sano, Satori Tokudome, Jin Endo, Takaharu Katayama, Kentaro Hayashida, Shinsuke Yuasa, Ruri Kaneda, Shinji Makino …

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 45 S32-S32 2008年10月
Activation of Phgdh-dependent serine biosynthesis plays a pivotal role in the induction by aldehyde of cardioprotection against oxidative stress

Motoaki Sano, Jin Endo, Takaharu Katayama, Keiichi Fukuda

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 45 S22-S23 2008年10月
Sublethal Levels of Aldehydes Augmented Cardiac Anti-Oxidant Defense through Activation of elF2 alpha-ATF4 Pathway via GCN2 Kinase

Takaharu Katayama, Motoaki Sano, Jin Endo, Kentaro Hayashida, Tomohiro Matsuhashi, Satori Tokudome, Toshimi Kageyama, Shinsuke Yuasa, Takeshi Adachi, Makoto Suematsu …

CIRCULATION 118(18) S320-S320 2008年10月
Kinases-dependent metabolic shift towards the Phgdh-mediated serine synthesis enhances cardioprotection to oxidative stress as hormesis to aldehydes

Takaharu Katayama, Jin Endo, Motoaki Sano, Kentaro Hayashida, Makoto Suematsu, Shigeo Ohta, Satoshi Ogawa, Keiichi Fukuda

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 45 S11-S11 2008年10月
Neural Crest Stem Cells Supply Intrinsic Cardiac Adrenergic Cells and Contribute to Reinnervation after Myocardial Infarction in Mice

Yuichi Tamura, Masaki Ieda, Keisuke Matsumura, Hideaki Kanazawa, Kensuke Kimura, Yasuyo Ieda, Jin Endo, Takahide Arai, Haruke Kawaguchi-Manabe, Yuichi Tomita …

CIRCULATION 118(18) S395-S395 2008年10月
Imprinting Gene-Modified Parthenogenic ES Cells Can be a Novel Autologous Cell Source for Generating Regenerative Cardiomyocytes

Toshimi Kageyama, Shinji Makino, Fumiyuki Hattori, Run Kaneda, Shinsuke Yuasa, Takeshi Onizuka, Sonhan Yun, Youhei Ohno, Jin Endo, Kenichirour Shimoji …

CIRCULATION 118(18) S491-S492 2008年10月
Glucocorticoid protects hearts from ischemia-reperfusion injury via activation of PGD2 biosynthesis

Hidenori Moriyama, Motoaki Sano, Satori Tokudome, Tomohiro Matsuhashi, Shintaro Morizane, Takaharu Katayama, Kentaro Hayashida, Jin Endo, Kehchi Fukuda, Satoshi Ogawa

JOURNAL OF CARDIAC FAILURE 14(7) S169-S169 2008年9月
Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury

Kentaro Hayashida, Motoaki Sano, Ikuroh Ohsawa, Ken Shinmura, Kayoko Tamaki, Kensuke Kimura, Jin Endo, Shigeo Ohta, Keiichi Fukuda, Satoshi Ogawa

JOURNAL OF CARDIAC FAILURE 14(7) S168-S168 2008年9月
Tissue histidine deprivation mediates cardiac antioxidant defense via activation of GCN2-eIF2-ATF4 pathway

Takaharu Katayama, Motoaki Sano, Jin Endo, Kentaro Hayashida, Tomohiro Matsuhashi, Satori Tokudome, Toshimi Kageyama, Takahide Arai, Keiichi Fukuda, Satoshi Ogawa

JOURNAL OF CARDIAC FAILURE 14(7) S164-S165 2008年9月
Activation of L-serine biosynthesis is indispensable for hormetic effects of aldehydes in the heart

Jin Endo, Motoaki Sano, Takaharu Katayama, Takeshi Adachi, Kentaro Hayashida, Shinsuke Yuasa, Shinji Makino, Makoto Suematsu, Keiichi Fukuda, Satoshi Ogawai

JOURNAL OF CARDIAC FAILURE 14(7) S149-S149 2008年9月
Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury

Kentaro Hayashida, Motoaki Sano, Ikuroh Ohsawa, Ken Shinmura, Kayoko Tamaki, Kensuke Kimura, Jin Endo, Takaharu Katayama, Akio Kawamura, Shun Kohsaka …

Biochemical and Biophysical Research Communications 373(1) 30-35 2008年8月15日
Inhalation of Hydrogen Gas Reduces Infarct Size in the Rat Model of Myocardial Ischemia-Reperfusion Injury

Kentaro Hayashida, Motoaki Sano, Ikuro Ohsawa, Ken Shinmura, Kayoko Tamaki, Kensuke Kimura, Jin Endo, Takaharu Katayama, Shigeo Ohta, Satoshi Ogawa …

CIRCULATION RESEARCH 103(5) E59-E60 2008年8月
Inherent Capacity of the Heart to Augment Antioxidant Defense via Activation of Amino Acid Metabolism as a Hormetic Response to Aldehydes

Motoaki Sano, Jin Endo, Takaharu Katayama, Keiichi Fukuda

CIRCULATION RESEARCH 103(5) E48-E48 2008年8月

もっとみる

共同研究・競争的資金等の研究課題

ミトコンドリア制御蛋白を介した心筋保護機構の解明および新規治療法の開発

日本学術振興会科学研究費助成事業基盤研究(C) 2021年4月 - 2024年3月

遠藤仁
サルコペニアの新規分子機構の解明と治療戦略の創出

日本学術振興会科学研究費助成事業基盤研究(C) 2018年4月 - 2021年3月

遠藤仁
心血管疾患における脂肪酸バランス制御の意義と機能の解明

日本学術振興会科学研究費助成事業若手研究(B) 2014年4月 - 2016年3月

遠藤仁
免疫老化への介入による新規循環器疾患治療戦略の確立

日本学術振興会科学研究費助成事業基盤研究(C) 2013年4月 - 2016年3月

新村健, 福田恵一, 佐野元昭, 遠藤仁
心臓のストレス応答における脂肪酸代謝の意義と機能についての網羅的解析

日本学術振興会科学研究費助成事業特別研究員奨励費 2011年 - 2013年

遠藤仁
骨髄osteoblastic-zoneにおける多能性幹細胞の心筋分化の解析

日本学術振興会科学研究費助成事業若手研究(B) 2005年 - 2006年

遠藤仁

遠藤仁

基本情報

研究キーワード

研究分野

経歴

論文

MISC

共同研究・競争的資金等の研究課題

メニュー

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