Research Projects

Apr, 2012 - Mar, 2015

The study of both the neural basis of meta-cogniton and meta-cognitive intervention in ocd patients

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)
  • HASHIMOTO NOBUHIKO
  • ,
  • NAKAAKI Shutaro
  • ,
  • NARUMOTO Jin
  • ,
  • MIMURA Masaru

Grant number
24530884
Japan Grant Number (JGN)
JP24530884
Grant amount
(Total)
4,290,000 Japanese Yen
(Direct funding)
3,300,000 Japanese Yen
(Indirect funding)
990,000 Japanese Yen

In this study, we examined the neural basis of meta-cognition in OCD patients. Next, we developed the new program of meta-cognitive intervention in behavior therapy-resistant OCD patients. .Twenty OCD patients participated in an open study testing the effectiveness of the meta-cognitive intervention. Patients with a reduction in their global Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score of 35% or greater were judged as being responsive to the treatment. Among 12 OCD patients, five OCD patients were defined as responders of the treatment. In addition, five OCD patients improved on scores of questionnaires of meta-cognition. Compared with responders (n=5), non-responders exhibited significantly worse of executive function at the time of baseline, and over-estimated the wasted time during the rituals. The new program of meta-cognitive intervention is likely to be beneficial to t behavior therapy-resistant OCD patients.

Link information
Kaken Url
https://kaken.nii.ac.jp/file/KAKENHI-PROJECT-24530884/24530884seika.pdf
KAKEN
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24530884
ID information
  • Grant number : 24530884
  • Japan Grant Number (JGN) : JP24530884