論文

査読有り 筆頭著者 最終著者 責任著者
2006年9月

Connectivity matrix method for analyses of biological networks and its application to atom-level analysis of a model network of carbohydrate metabolism

IEE PROCEEDINGS SYSTEMS BIOLOGY
  • J. Ohta

153
5
開始ページ
372
終了ページ
374
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1049/ip-syb:20060018
出版者・発行元
INSTITUTION ENGINEERING TECHNOLOGY-IET

An approach for analysis of biological networks is proposed. In this approach, named the connectivity matrix (CM) method, all the connectivities of interest are expressed in a matrix. Then, a variety of analyses are performed on GNU Octave or Matlab. Each node in the network is expressed as a row vector or numeral that carries information defining or characterising the node itself Information about connectivity itself is also expressed as a row vector or numeral. Thus, connection of node n(1) to node n(2) through edge e is expressed as [n(1), n(2), e], a row vector formed by the combination of three row vectors or numerals, where n(1), n(2) and e indicate two different nodes and one connectivity, respectively. All the connectivities in any given network are expressed as a matrix, CM, each row of which corresponds to one connectivity. Using this CM method, intermetabolite atom-level connectivity is investigated in a model metabolic network composed of the reactions for glycolysis, oxidative decarboxylation of pyruvate, citric acid cycle, pentose phosphate pathway and gluconeogenesis.

リンク情報
DOI
https://doi.org/10.1049/ip-syb:20060018
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000240324600016&DestApp=WOS_CPL
URL
http://www.cc.okayama-u.ac.jp/~jo25/imac/btk2006/
ID情報
  • DOI : 10.1049/ip-syb:20060018
  • ISSN : 1741-2471
  • Web of Science ID : WOS:000240324600016

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