Jun Ohshima

Profile Information

Affiliation: Graduate School of Dentistry, Osaka University

Degree: 博士（歯学）(大阪大学)

Researcher number: 30755450
J-GLOBAL ID: 201801003654690682
researchmap Member ID: B000313077

Research Areas

Research History

Nov, 2020 - Present

講師, 大阪大学歯学部附属病院保存科
Apr, 2018 - Present

助教, 歯学研究科, 大阪大学大学院
May, 2015 - Present

Assistant professor, Graduate School of Dentistry, Osaka University
Apr, 2016 - Mar, 2018

Research Scholar, University of Louisville
Apr, 2015 - Apr, 2015

Research and Clinical Fellow, Osaka University Dental Hospital
Apr, 2010 - Mar, 2011

Resident, Osaka University Dental Hospital

Education

Apr, 2011 - Mar, 2015

Graduate School of Dentistry, Osaka University

Awards

Jun, 2016

日本歯科保存学会奨励賞, 日本歯科保存学会

大嶋淳
Mar, 2016

研究科長賞（平成27年度研究部門）, 大阪大学大学院歯学研究科

大嶋淳
Oct, 2015

JADR/GC学術奨励賞, 国際歯科研究学会日本部会（Japanese Association for Dental Research：JADR）

大嶋淳

Papers

ニッケルチタンファイルFKGレイスによる根管形成実習の教育効果第2報：湾曲根管模型（J型およびS型）を用いた根管形成の習熟度について.

大嶋淳, 川西雄三, 岡真太郎, 山田朋美, 山口幹代, 朝日陽子, 外園真規, 鍵岡琢実, 渡邉昌克, 内藤克昭, 阿部翔大郎, 上村怜央, 高橋雄介, 伊藤祥作, 林美加子

日本歯科保存学会誌, 62(6) 263-270, Dec, 2019 Peer-reviewedLead author
Porphyromonas gingivalis Tyrosine Phosphatase Php1 Promotes Community Development and Pathogenicity.

Jung YJ, Miller DP, Perpich JD, Fitzsimonds ZR, Shen D, Ohshima J, Lamont RJ

mBio, 10(5) e02004-e02019, Sep, 2019 Peer-reviewed
Streptococcus gordonii programs epithelial cells to resist ZEB2 induction by Porphyromonas gingivalis

Ohshima J, Wang Q, Fitzsimonds ZR, Miller DP, Sztukowska MN, Jung YJ, Hayashi M, Whiteley M, Lamont RJ

Proc Natl Acad Sci U S A, 116(17) 8544-8553, Apr, 2019 Peer-reviewed
p62 Plays a Specific Role in Interferon-gamma-Induced Presentation of a Toxoplasma Vacuolar Antigen

Youngae Lee, Miwa Sasai, Ji Su Ma, Naoya Sakaguchi, Jun Ohshima, Hironori Bando, Tatsuya Saitoh, Shizuo Akira, Masahiro Yamamoto

CELL REPORTS, 13(2) 223-233, Oct, 2015 Peer-reviewed
RabGDI alpha is a negative regulator of interferon-gamma-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii

Jun Ohshima, Miwa Sasai, Jianfa Liu, Kazuo Yamashita, Ji Su Ma, Youngae Lee, Hironori Bando, Jonathan C. Howard, Shigeyuki Ebisu, Mikako Hayashi, Kiyoshi Takeda, Daron M. Standley, Eva-Maria Frickeli, Masahiro Yamamoto

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(33) E4581-E4590, Aug, 2015 Peer-reviewed
mTOR Complex Signaling through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8(+) T Cells

Daisuke Ito, Satoshi Nojima, Masayuki Nishide, Tatsusada Okuno, Hyota Takamatsu, Sujin Kang, Tetsuya Kimura, Yuji Yoshida, Keiko Morimoto, Yohei Maeda, Takashi Hosokawa, Toshihiko Toyofuku, Jun Ohshima, Daisuke Kamimura, Masahiro Yamamoto, Masaaki Murakami, Eiichi Morii, Hiromi Rakugi, Yoshitaka Isaka, Atsushi Kumanogoh

JOURNAL OF IMMUNOLOGY, 195(3) 934-943, Aug, 2015 Peer-reviewed
インターフェロンγ誘導性GTPaseとトキソプラズマ感染防御

大嶋淳, 笹井美和, 山本雅裕

医学のあゆみ, 249(13) 1325-1326, Sep, 2014
Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6

Ji Su Ma, Miwa Sasai, Jun Ohshima, Youngae Lee, Hironori Bando, Kiyoshi Takeda, Masahiro Yamamoto

JOURNAL OF EXPERIMENTAL MEDICINE, 211(10) 2013-2032, Sep, 2014 Peer-reviewed
Role of Mouse and Human Autophagy Proteins in IFN-gamma-Induced Cell-Autonomous Responses against Toxoplasma gondii

Jun Ohshima, Youngae Lee, Miwa Sasai, Tatsuya Saitoh, Ji Su Ma, Naganori Kamiyama, Yoshiharu Matsuura, Suh Pann-Ghill, Mikako Hayashi, Shigeyuki Ebisu, Kiyoshi Takeda, Shizuo Akira, Masahiro Yamamoto

JOURNAL OF IMMUNOLOGY, 192(7) 3328-3335, Apr, 2014 Peer-reviewed
CREBH Determines the Severity of Sulpyrine-Induced Fatal Shock

Naganori Kamiyama, Masahiro Yamamoto, Hiroyuki Saiga, Ji Su Ma, Jun Ohshima, Sakaaki Machimura, Miwa Sasai, Taishi Kimura, Yoshiyasu Ueda, Hisako Kayama, Kiyoshi Takeda

PLoS ONE, 8(2) e55800, Feb 7, 2013 Peer-reviewed
A Cluster of Interferon-gamma-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

Masahiro Yamamoto, Megumi Okuyama, Ji Su Ma, Taishi Kimura, Naganori Kamiyama, Hiroyuki Saiga, Jun Ohshima, Miwa Sasai, Hisako Kayama, Toru Okamoto, David C. S. Huang, Dominique Soldati-Favre, Kyoji Horie, Junji Takeda, Kiyoshi Takeda

IMMUNITY, 37(2) 302-313, Aug, 2012 Peer-reviewed

Presentations

Porphyromonas gingivalisはβ-カテニンシグナルを介して歯肉上皮細胞に上皮間葉転換を誘導する

大嶋淳

第94回日本細菌学会総会細菌学若手コロッセウム, Mar 23, 2021 Invited
Porphyromonas gingivalis induces mesenchymal-like transition through beta-catenin signaling.

Jun Ohshima

Joint Research Symposium of Osaka University and Newcastle University, Dec 3, 2020 Invited
Porphyromonas gingivalis Induces Mesenchymal-like Transition Through Beta-catenin Signaling

Ohshima J, Hayashi M, Lamont RJ

97th International Association for Dental Research General Session, Jun 21, 2019
Streptococcus gordonii antagonizes Porphyromonas gingivalis-mediated signaling in epithelial cells

Fitzsimonds ZR, Ohshima J, Wang Q, Sztukowska MN, Miller DP, Lamont RJ

97th International Association for Dental Research General Session, Jun 19, 2019
ニッケルチタンファイルFKGレイスによる湾曲根管形成実習の教育効果第三報：2種類のロータリーエンジンを用いた根管形成の習熟度について

川西雄三, 大嶋淳, 岡真太郎, 外園真規, 山口幹代, 山田朋美, 朝日陽子, 鍵岡琢実, 渡邉昌克, 内藤克昭, 天羽萌, 田中亮佑, 林美加子

第40回日本歯内療法学会学術大会, Jun 16, 2019
Porphyromonas gingivalis はβ-カテニンシグナルを介して歯肉上皮細胞に上皮間葉転換を誘導する

大嶋淳, 林美加子

第148回日本歯科保存学会春季学術大会, Jun 15, 2018
How UVA-activated Riboflavin Inhibits Demineralization of Human Dentin

Uemura R, Yagi K, Shinno Y, Ohshima J, Miura J, Matsuda Y, Hayashi M

2017 IADR General Session & Exhibition, Mar 25, 2017
RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii

Miwa Sasai, Jun Ohshima, Ji Su Ma, Youngae Lee, Kiyoshi Takeda, Masahiro Yamamoto

The 44th Annual Meeting of The Japanese Society for Immunology, Nov 18, 2015
p62 plays a specific role in IFN-g-induced presentation of a Toxoplasma vacuolar antigen

Youngae Lee, Miwa Sasai, Ji Su Ma, Naoya Sakaguchi, Jun Ohshima, Hironori Bando, Tatsuya Saitoh, Shizuo Akira, Masahiro Yamamoto

The 44th Annual Meeting of The Japanese Society for Immunology, Nov 18, 2015
p62 plays a specific role in IFN-g-induced presentation of a Toxoplasma vacuolar antigen

Youngae Lee, Miwa Sasai, Ji Su Ma, Naoya Sakaguchi, Jun Ohshima, Hironori Bando, Tatsuya Saitoh, Shizuo Akira, Masahiro Yamamoto

Forum Cheju17, Nov 13, 2015
Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6

Ji Su Ma, Miwa Sasai, Jun Ohshima, Youngae Lee, Hironori Bando, Kiyoshi Takeda, Masahiro Yamamoto

Forum Cheju17, Nov 13, 2015
RabGDIαはインターフェロン－ガンマ誘導性GTPaseによる細胞内寄生性病原体の排除を制御する

大嶋淳, 野杁由一郎, 山本雅裕, 林美加子

第142回日本歯科保存学会春季学術大会, Jun 25, 2015
トキソプラズマ原虫の多型濃縮顆粒タンパク質GRA6による選択的NFAT4の活性化について

馬知秀, 笹井美和, 大嶋淳, 李英愛, 伴戸寛徳, 竹田潔, 山本雅裕

第84回日本寄生虫学会大会, Mar 22, 2015
肝臓期マラリア原虫を標的とした新規抗マラリア薬の開発

伴戸寛徳, 笹井美和, 馬知秀, 大嶋淳, 李英愛, 山本雅裕

第84回日本寄生虫学会大会, Mar 21, 2015
Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6

Ma JS, Sasai M, Ohshima J, Lee Y, Bando H, Takeda K, Yamamoto M

Feb 28, 2015
RabGDIa is a negative regulator of interferon-g-inducible GTPase-dependent cell-autonomous host defense against Toxoplasma gondii

Ohshima J, Sasai M, Ma JS, Lee Y, Bando H, Takeda K, Yamamoto M

Feb 27, 2015
Negative regulation of interferon-inducible GTPase-mediated immunity and inflammation

Jun Ohshima

Jan 30, 2015
Toxoplasma gondii GRA6 selectively activates NFAT4 to induce chemokine CXCL2 and CCL2

Sasai M, Ma JS, Ohshima J, Lee Y, Yamamoto M

Dec 12, 2014
Human ATG16L1 and GBPs are dispensable for IFN-g-dependent anti-Toxoplasma gondii responses

Lee Y, Ohshima J, Sasai M, Ma JS, Yamamoto M

Dec 12, 2014
Role of mouse autophagy proteins in IFN-g-mediated cell-autonomous responses against Toxoplasma gondii

Ohshima J, Lee Y, Sasai M, Ma JS, Takeda K, Yamamoto M

Dec 12, 2014

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