鈴木純二 (Junji Suzuki) - マイポータル

基本情報

所属: Washington University in St. Louis Department of Biochemistry and Molecular Biophysics Visiting Research Associate

ORCID iD: https://orcid.org/0000-0003-1648-5471
J-GLOBAL ID: 201701004786888715
researchmap会員ID: B000276521

研究分野

論文

Screening for novel RyR2 inhibitors by ER Ca²⁺monitoring

Mai Takenaka, Masami Kodama, Takashi Murayama, Mari Ishigami-Yuasa, Shuichi Mori, Ryosuke Ishida, Junji Suzuki, Kazunori Kanemaru, Masami Sugihara, Masamitsu Iino …

Molecular Pharmacology MOLPHARM-AR 2023年9月7日
Cytosolic Ca2+-dependent Ca2+ release activity primarily determines the ER Ca2+ level in cells expressing the CPVT-linked mutant RYR2

Nagomi Kurebayashi, Takashi Murayama, Ryosaku Ota, Junji Suzuki, Kazunori Kanemaru, Takuya Kobayashi, Seiko Ohno, Minoru Horie, Masamitsu Iino, Fumiyoshi Yamashita …

Journal of General Physiology 154(9) 2022年9月5日
Mitochondrial uncouplers induce proton leak by activating AAC and UCP1.

Ambre M Bertholet, Andrew M Natale, Paola Bisignano, Junji Suzuki, Andriy Fedorenko, James Hamilton, Tatiana Brustovetsky, Lawrence Kazak, Ryan Garrity, Edward T Chouchani …

Nature 606(7912) 180-187 2022年6月
Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR mutant lung cancer.

Shigeki Nanjo, Wei Wu, Niki Karachaliou, Collin M Blakely, Junji Suzuki, Yu-Ting Chou, Siraj M Ali, D Lucas Kerr, Victor R Olivas, Jonathan Shue …

The Journal of clinical investigation 132(13) 2022年5月17日
The mechanism of MICU-dependent gating of the mitochondrial Ca2+uniporter.

Vivek Garg, Junji Suzuki, Ishan Paranjpe, Tiffany Unsulangi, Liron Boyman, Lorin S Milescu, W Jonathan Lederer, Yuriy Kirichok

eLife 10 2021年8月31日
Red fluorescent CEPIA indicators for visualization of Ca2+ dynamics in mitochondria.

Kazunori Kanemaru, Junji Suzuki, Isamu Taiko, Masamitsu Iino

Scientific reports 10(1) 2835-2835 2020年2月18日
Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics.

Toshiko Yamazawa, Haruo Ogawa, Takashi Murayama, Maki Yamaguchi, Hideto Oyamada, Junji Suzuki, Nagomi Kurebayashi, Kazunori Kanemaru, Katsuji Oguchi, Takashi Sakurai …

The Journal of general physiology 152(1) 2020年1月6日
Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers.

Nilanjana Chatterjee, Evangelos Pazarentzos, Manasi K Mayekar, Philippe Gui, David V Allegakoen, Gorjan Hrustanovic, Victor Olivas, Luping Lin, Erik Verschueren, Jeffrey R Johnson …

Cell reports 28(9) 2317-2330 2019年8月27日
Inositol 1,4,5-trisphosphate receptor type 2-independent Ca2+ release from the endoplasmic reticulum in astrocytes.

Yohei Okubo, Kazunori Kanemaru, Junji Suzuki, Kenta Kobayashi, Kenzo Hirose, Masamitsu Iino

Glia 67(1) 113-124 2019年1月
Efficient High-Throughput Screening by Endoplasmic Reticulum Ca2+ Measurement to Identify Inhibitors of Ryanodine Receptor Ca2+-Release Channels.

Takashi Murayama, Nagomi Kurebayashi, Mari Ishigami-Yuasa, Shuichi Mori, Yukina Suzuki, Ryunosuke Akima, Haruo Ogawa, Junji Suzuki, Kazunori Kanemaru, Hideto Oyamada …

Molecular pharmacology 94(1) 722-730 2018年7月
Genotype-Phenotype Correlations of Malignant Hyperthermia and Central Core Disease Mutations in the Central Region of the RYR1 Channel.

Takashi Murayama, Nagomi Kurebayashi, Haruo Ogawa, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, Takashi Sakurai

Human mutation 37(11) 1231-1241 2016年11月
Genetically Encoded Fluorescent Indicators for Organellar Calcium Imaging.

Junji Suzuki, Kazunori Kanemaru, Masamitsu Iino

Biophysical journal 111(6) 1119-1131 2016年9月20日
Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death.

Yoshinori Mikami, Kazunori Kanemaru, Yohei Okubo, Takuya Nakaune, Junji Suzuki, Kazuki Shibata, Hiroki Sugiyama, Ryuta Koyama, Takashi Murayama, Akihiro Ito …

EBioMedicine 11 253-261 2016年9月
Visualization of Ca2+ Filling Mechanisms upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells.

Yohei Okubo, Junji Suzuki, Kazunori Kanemaru, Naotoshi Nakamura, Tatsuo Shibata, Masamitsu Iino

The Journal of neuroscience : the official journal of the Society for Neuroscience 35(48) 15837-46 2015年12月2日
Neuronal Regulation of Schwann Cell Mitochondrial Ca(2+) Signaling during Myelination.

Daisuke Ino, Hiroshi Sagara, Junji Suzuki, Kazunori Kanemaru, Yohei Okubo, Masamitsu Iino

Cell reports 12(12) 1951-9 2015年9月29日
Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region.

Takashi Murayama, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, Takashi Sakurai

PloS one 10(6) e0130606 2015年
Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA.

Junji Suzuki, Kazunori Kanemaru, Kuniaki Ishii, Masamichi Ohkura, Yohei Okubo, Masamitsu Iino

Nature communications 5 4153-4153 2014年6月13日

MISC

Molecular Dynamics and Ca2+ Imaging of Mutant Type 1 Ryanodine Receptor

Toshiko Yamazawa, Haruo Ogawa, Takashi Murayama, Maki Yamaguchi, Hideto Oyamada, Junji Suzuki, Nagomi Kurebayashi, Kanemaru Kazunori, Takashi Sakurai, Masamitsu Iino

BIOPHYSICAL JOURNAL 118(3) 98A-98A 2020年2月
Investigation of Mutant Ryanodine Receptor Channel Activity using Functional Analysis and Molecular Dynamics

Toshiko Yamazawa, Haruo Ogawa, Maki Yamaguchi, Takashi Murayama, Hideto Oyamada, Junji Suzuki, Nagomi Kurebayashi, Kazunori Kanemaru, Takashi Sakurai, Iino Masamitsu

BIOPHYSICAL JOURNAL 116(3) 521A-522A 2019年2月
小胞体内Ca2+濃度測定を利用した新規RyR1阻害薬のハイスループットスクリーニング

村山尚, 呉林なごみ, 湯浅磨里, 石上, 森修一, 鈴木志奈, 秋間龍之介, 小川治夫, 鈴木純二, 金丸和典 …

日本筋学会学術集会プログラム・抄録集 4回 180-180 2018年8月
Search for Type 2 Ryanodine Receptor Inhibitor by Monitoring Endoplasmic Reticulum Ca2+

Mai Tamura, Nagomi Kurebayashi, Takashi Murayama, Shuichi Mori, Mari Ishigami-Yuasa, Hiroyuki Kagechika, Junji Suzuki, Kazunori Kanemaru, Masamitsu Iino, Takashi Sakurai

BIOPHYSICAL JOURNAL 114(3) 116A-116A 2018年2月
Visualization of Ca2+ dynamics within the endoplasmic reticulum for the investigation of neuronal and astrocytic functions

Okubo Yohei, Suzuki Junji, Kanemaru Kazunori, Nakamura Naotoshi, Shibata Tatsuo, Lino Masamitsu

JOURNAL OF PHARMACOLOGICAL SCIENCES 130(3) S24 2016年3月査読有り
Intra-organellar Ca2+ Signaling Imaged Using Genetically Encoded Ca2+ Indicators CEPIA

Suzuki Junji, Kanemaru Kazunori, Ishii Kuniaki, Ohkura Masamichi, Okubo Yohei, Iino Masamitsu

JOURNAL OF PHARMACOLOGICAL SCIENCES 130(3) S252 2016年3月査読有り
Alterations in neuronal mitochondrial functions in response to nitric oxide-induced Ca2+ release via type 1 ryanodine receptor

Takuya Nakaune, Junji Suzuki, Yoshinori Mikami, Kazunori Kanemaru, Masamitsu Iino

JOURNAL OF PHARMACOLOGICAL SCIENCES 130(3) S191-S191 2016年3月
Characterization of Ca2+ - Induced Ca2+ Release via RyR2 Carrying Arrhythmogenic Mutations

Nagomi Kurebayashi, Takashi Murayama, Junji Suzuki, Kazunori Kanemaru, Masamitsu Iino, Takashi Sakurai

BIOPHYSICAL JOURNAL 110(3) 268A-268A 2016年2月
S4-S5 Linker Regulates RyR2 Channel Gating through Multiple Interactions

Takashi Murayama, Nagomi Kurebayashi, Haruo Ogawa, Junji Suzuki, Kazunori Kanemam, Masamitsu Iino, Takashi Sakurai

BIOPHYSICAL JOURNAL 110(3) 97A-97A 2016年2月
Correlation of Molecular Dynamics Analysis and Calcium Signaling in Mutant Ryanodine Receptors

Toshiko Yamazawa, Takashi Murayama, Hideto Oyamada, Junji Suzuki, Nagomi Kurebayashi, Kazunori Kanemaru, Maki Yamaguchi, Chikara Sato, Masamitsu Iino

BIOPHYSICAL JOURNAL 110(3) 263A-263A 2016年2月
一酸化窒素は1型リアノジン受容体のS-ニトロシル化修飾を介して神経細胞死を誘導する

三上義礼, 三上義礼, 金丸和典, 大久保洋平, 中畝拓哉, 鈴木純二, 柿澤昌, 村山尚, 柴田和輝, 小山隆太 …

日本分子生物学会年会プログラム・要旨集(Web) 39th 2016年
Effects of Arrhythmogenic Mutations on Ca2+-Induced Ca2+ Release Activities of Type 2 Ryanodine Receptors

Kurebayashi Nagomi, Murayama Takashi, Suzuki Junji, Kanemaru Kazunori, Iino Masamitsu, Sakurai Takashi

BIOPHYSICAL JOURNAL 108(2) 568A 2015年1月27日
Effects of MH and CCD Mutations in the Central Region on RyR1 Channels

Murayama Takashi, Kurebayashi Nagomi, Yamazawa Toshiko, Oyamada Hideto, Suzuki Junji, Kanemaru Kazunori, Oguchi Katsuji, Iino Masamitsu, Sakurai Takashi

BIOPHYSICAL JOURNAL 108(2) 270A-271A 2015年1月27日
FUNCTIONAL ANALYSIS OF RYANODINE RECEPTOR CARRYING MALIGNANT HYPERTHERMIA ASSOCIATED MUTATIONS

T. Yamazawa, T. Murayama, H. Oyamada, J. Suzuki, N. Kurebayashi, K. Kanemaru, K. Oguchi, T. Sakurai, S. Takemori, M. Iino

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 115 263-263 2014年7月
Analysis of Ca2+ dynamics in the endoplasmic reticulum and mitochondria in pancreatic beta-cells

Tsubasa Nishikawa, Junji Suzuki, Kazunori Kanemaru, Masamitsu Iino

JOURNAL OF PHARMACOLOGICAL SCIENCES 124 200P-200P 2014年
Ca2+ release properties of arrhythmogenic ryanodine receptor type 2 mutants

Nagomi Kurebayashi, Takashi Murayama, Junji Suzuki, Kazunori Kanemaru, Masamitsu Iino, Takashi Sakurai

JOURNAL OF PHARMACOLOGICAL SCIENCES 124 133P-133P 2014年
Imaging of activity-dependent Ca2+ dynamics in the endoplasmic reticulum of Purkinje cells

Yohei Okubo, Junji Suzuki, Kazunori Kanemaru, Masamitsu Iino

JOURNAL OF PHARMACOLOGICAL SCIENCES 124 122P-122P 2014年
Mitochondrial calcium signaling in Schwann cells mediates myelination in the peripheral nervous system

Daisuke Ino, Hiroshi Sagara, Junji Suzuki, Kazunori Kanemaru, Yohei Okubo, Masamitsu Iino

JOURNAL OF PHARMACOLOGICAL SCIENCES 124 146P-146P 2014年
Imaging of Ca2+ dynamics within the endoplasmic reticulum and mitochondria using new GFP-based fluorescent Ca2+ indicators

Suzuki Junji, Kanemaru Kazunori, Ishii Kuniaki, Ohkura Masamichi, Okubo Yohei, Iino Masamitsu

JOURNAL OF PHARMACOLOGICAL SCIENCES 124 92P 2014年査読有り
Functional analysis of type 1 ryanodine receptor carrying N-terminal malignant hyperthermia associated mutations

Toshiko Yamazawa, Takashi Murayama, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Nagomi Kurebayashi, Katsuji Oguchi, Takashi Sakurai, Shigeru Takemoril, Masamitsu Iino

JOURNAL OF PHARMACOLOGICAL SCIENCES 124 137P-137P 2014年

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鈴木純二

基本情報

研究分野

論文

MISC

メニュー

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