Junji Yamaguchi - My portal

Profile Information

Affiliation: 助教, 形態解析イメージング研究室, 順天堂大学

Researcher number: 30875282
J-GLOBAL ID: 202001000872768234
researchmap Member ID: R000014439

Papers

Improved volume CLEM revealed that aberrant phagophores and RB1CC1/FIP200-containing clusters appear surround SQSTM1/p62 aggregates in Atg9a-deficient cells

Soichiro Kakuta, Junji Yamaguchi, Chigure Suzuki, Isei Tanida, Yasuo Uchiyama

Autophagy Reports, 2(1), Sep 15, 2023
TUNEL-positive structures in activated microglia and SQSTM1/p62-positive structures in activated astrocytes in the neurodegenerative brain of a CLN10 mouse model.

Shun Mitsui, Junji Yamaguchi, Chigure Suzuki, Yasuo Uchiyama, Isei Tanida

Glia, Aug 12, 2023
Application of immuno- and affinity labeling with fluorescent dyes to in-resin CLEM of Epon-embedded cells.

Isei Tanida, Junji Yamaguchi, Chigure Suzuki, Soichiro Kakuta, Yasuo Uchiyama

Heliyon, 9(6) e17394, Jun, 2023
Recent advances in in-resin correlative light and electron microscopy of Epon-embedded cells.

Isei Tanida, Junji Yamaguchi, Chigure Suzuki, Soichiro Kakuta, Yasuo Uchiyama

Microscopy (Oxford, England), May 22, 2023
Osmium-Resistant Fluorescent Proteins and In-Resin Correlative Light-Electron Microscopy of Epon-Embedded Mammalian Cultured Cells.

Isei Tanida, Junji Yamaguchi, Soichiro Kakuta, Yasuo Uchiyama

Methods in molecular biology (Clifton, N.J.), 2564 287-297, 2023
GPHR-mediated acidification of the Golgi lumen is essential for cholesterol biosynthesis in the brain.

Yu-Shin Sou, Junji Yamaguchi, Hiroshi Kameda, Keisuke Masuda, Yusuke Maeda, Yasuo Uchiyama, Masato Koike

FEBS letters, Sep 3, 2022
Lack of Cathepsin D in the central nervous system results in microglia and astrocyte activation and the accumulation of proteinopathy-related proteins.

Chigure Suzuki, Junji Yamaguchi, Takahito Sanada, Juan Alejandro Oliva Trejo, Souichirou Kakuta, Masahiro Shibata, Isei Tanida, Yasuo Uchiyama

Scientific reports, 12(1) 11662-11662, Jul 8, 2022
In-resin CLEM of Epon-embedded cells using proximity labeling.

Takahito Sanada, Junji Yamaguchi, Yoko Furuta, Soichiro Kakuta, Isei Tanida, Yasuo Uchiyama

Scientific reports, 12(1) 11130-11130, Jul 1, 2022
Membranous Structures Directly Come in Contact With p62/SQSTM1 Bodies.

Isei Tanida, Tomohiro Haruta, Mitsuo Suga, Shunsuke Takei, Akira Takebe, Yoko Furuta, Junji Yamaguchi, Juan Alejandro Oliva Trejo, Soichiro Kakuta, Yasuo Uchiyama

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 69(6) 407-414, Jun, 2021
Homeostatic p62 levels and inclusion body formation in CHCHD2 knockout mice.

Shigeto Sato, Sachiko Noda, Satoru Torii, Taku Amo, Aya Ikeda, Manabu Funayama, Junji Yamaguchi, Takahiro Fukuda, Hiromi Kondo, Norihiro Tada …

Human molecular genetics, 30(6) 443-453, Apr 30, 2021
Three-Dimensional Architecture of Glomerular Endothelial Cells Revealed by FIB-SEM Tomography

Yuto Kawasaki, Yasue Hosoyamada, Takayuki Miyaki, Junji Yamaguchi, Soichiro Kakuta, Tatsuo Sakai, Koichiro Ichimura

Frontiers in Cell and Developmental Biology, 9, Mar 11, 2021
Application of Conventional FE-SEM to Podocyte Structural Analysis: Protocol and Usage Examples

Yuto Kawasaki, Takayuki Miyaki, Junji Yamaguchi, Soichiro Kakuta, Yasue Hosoyamada, Tatsuo Sakai, Koichiro Ichimura

Juntendo Medical Journal, 67(1) 2-9, 2021 Peer-reviewed
Two-color in-resin CLEM of Epon-embedded cells using osmium resistant green and red fluorescent proteins.

Isei Tanida, Yoko Furuta, Junji Yamaguchi, Soichiro Kakuta, Juan Alejandro Oliva Trejo, Yasuo Uchiyama

Scientific reports, 10(1) 21871-21871, Dec 14, 2020
DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria.

Kentaro Ozawa, Hiroki Tsumoto, Yuri Miura, Junji Yamaguchi, Sanae M M Iguchi-Ariga, Tetsushi Sakuma, Takashi Yamamoto, Yasuo Uchiyama

Scientific reports, 10(1) 4377-4377, Mar 9, 2020
Elavl3 regulates neuronal polarity through the alternative splicing of an embryo-specific exon in AnkyrinG.

Yuki Ogawa, Junji Yamaguchi, Masato Yano, Yasuo Uchiyama, Hirotaka James Okano

Neuroscience research, 135 13-20, Oct, 2018
Elavl3 is essential for the maintenance of Purkinje neuron axons.

Yuki Ogawa, Kyoko Kakumoto, Tetsu Yoshida, Ken-Ichiro Kuwako, Taisuke Miyazaki, Junji Yamaguchi, Ayumu Konno, Junichi Hata, Yasuo Uchiyama, Hirokazu Hirai …

Scientific reports, 8(1) 2722-2722, Feb 9, 2018
Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis.

Junji Yamaguchi, Chigure Suzuki, Tomohisa Nanao, Soichirou Kakuta, Kentarou Ozawa, Isei Tanida, Tatsuya Saitoh, Takehiko Sunabori, Masaaki Komatsu, Keiji Tanaka …

Autophagy, 14(5) 764-777, 2018
Small GTPase Rab1B is associated with ATG9A vesicles and regulates autophagosome formation.

Soichiro Kakuta, Junji Yamaguchi, Chigure Suzuki, Mitsuho Sasaki, Saiko Kazuno, Yasuo Uchiyama

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(9) 3757-3773, Sep, 2017
Purkinje Cells Are More Vulnerable to the Specific Depletion of Cathepsin D Than to That of Atg7.

Masato Koike, Masahiro Shibata, Takehiko Sunabori, Junji Yamaguchi, Kenji Sakimura, Masaaki Komatsu, Keiji Tanaka, Yasuo Uchiyama

The American journal of pathology, 187(7) 1586-1600, Jul, 2017
Role of the NMDA receptor GluN2D subunit in the expression of ketamine-induced behavioral sensitization and region-specific activation of neuronal nitric oxide synthase.

Toshifumi Yamamoto, Tomomi Nakayama, Junji Yamaguchi, Maaya Matsuzawa, Masayoshi Mishina, Kazutaka Ikeda, Hideko Yamamoto

Neuroscience letters, 610 48-53, Jan 1, 2016

Misc.

RNA代謝異常により引き起こされる神経変性疾患の機序解析

小川優樹, 山口隼司, 鐘ヶ江裕美, 内山安男, 岡野ジェイムス洋尚

東京慈恵会医科大学雑誌, 132(6) 144-144, Nov, 2017
カテプシンD欠損マウスにおける腎臓と肝臓の生後成長障害について

鈴木ちぐれ, 七尾友久, 山口隼司, 内山安男, 柴田昌宏

日本透析医学会雑誌, 48(Suppl.1) 712-712, May, 2015
カテプシンD欠損マウスにおける腎臓と肝臓の生後成長障害について

鈴木ちぐれ, 七尾友久, 山口隼司, 柴田昌宏, 内山安男

日本腎臓学会誌, 57(3) 600-600, Apr, 2015
オートファジーモニタリングトランスジェニックマウスの作製およびTGマウス神経軸索終末部の解析

佐々木光穂, 山口隼司, 多村博澄, 多田昇弘, 内山安男

順天堂醫事雑誌, 59(6) 531-532, Dec, 2013
初代培養神経細胞の成熟過程におけるリソソームの局在動態について

七尾友久, 小池正人, 山口隼司, 砂堀毅彦, 佐々木光穂, 内山安男

順天堂醫事雑誌, 59(6) 532-532, Dec, 2013
軸索/シナプス前領域におけるAtg9Aを含む膜小胞成分の解析

山口隼司, 佐々木光穂, 小池正人, 七尾友久, 砂堀毅彦, 内山安男

順天堂醫事雑誌, 59(6) 533-533, Dec, 2013

Research Projects

神経性セロイドリポフスチン症の原因遺伝子欠損に基づくオートファジー新規役割の解析

科学研究費助成事業, 若手研究, 日本学術振興会, Apr, 2021 - Mar, 2023

山口隼司
Investigation of the new role of autophagy in the loss of lysosomal protease

Grants-in-Aid for Scientific Research, Grant-in-Aid for Research Activity Start-up, Japan Society for the Promotion of Science, Sep, 2020 - Mar, 2022

Yamaguchi Junji