山村和彦 (Kazuhiko Yamamura) - マイポータル

Extracellular ATP Contributes to Barrier Function and Inflammation in Atopic Dermatitis: Potential for Topical Treatment of Atopic Dermatitis by Targeting Extracellular ATP.

Kazuhiko Yamamura, Fumitaka Ohno, Shu Yotsumoto, Yuki Sato, Nanae Kimura, Kiichiro Nishio, Keiichi Inoue, Toshio Ichiki, Yoko Kuba-Fuyuno, Kei Fujishima …

International journal of molecular sciences 25(22) 2024年11月15日

Difamilast, a Topical Phosphodiesterase 4 Inhibitor, Produces Soluble ST2 via the AHR-NRF2 Axis in Human Keratinocytes.

Gaku Tsuji, Ayako Yumine, Koji Kawamura, Masaki Takemura, Makiko Kido-Nakahara, Kazuhiko Yamamura, Takeshi Nakahara

International journal of molecular sciences 25(14) 2024年7月19日

Gram‐negative anaerobes elicit a robust keratinocytes immune response with potential insights into <scp>HS</scp> pathogenesis

Samuel C. Williams, Sandra Garcet, Hong Hur, Shunsuke Miura, Juana Gonzalez, Kristina Navrazhina, Mika Yamamura‐Murai, Kazuhiko Yamamura, Xuan Li, John Frew …

Experimental Dermatology 33(5) 2024年4月29日

The therapeutic AHR-modulating agent Tapinarof regulates semaphorin 3A expression in human keratinocytes via NRF2.

Gaku Tsuji, Ayako Yumine, Kazuhiko Yamamura, Masaki Takemura, Makiko Kido-Nakahara, Takamichi Ito, Takeshi Nakahara

The Journal of investigative dermatology 2023年10月12日

Regulatory Mechanism of the IL-33-IL-37 Axis via Aryl Hydrocarbon Receptor in Atopic Dermatitis and Psoriasis.

Gaku Tsuji, Kazuhiko Yamamura, Koji Kawamura, Makiko Kido-Nakahara, Takamichi Ito, Takeshi Nakahara

International journal of molecular sciences 24(19) 2023年9月27日

Staphylococcus Aureus and Streptococcus Pyogenes Induce Psoriasis-Related Transcriptomes Augmented by IL-17A and TNF-α.

Shunsuke Miura, Yohei Ichimura, Uri Sela, Sandra Garcet, Charissa Salud-Gnilo, Xuan Li, Juana Gonzalez, Mika Murai-Yamamura, Kazuhiko Yamamura, Darshna Rambhia …

The Journal of investigative dermatology 143(8) 1613-1617 2023年8月

Cathelicidin Antimicrobial Peptide LL37 Induces Toll-Like Receptor 8 and Amplifies IL-36γ and IL-17C in Human Keratinocytes.

Shunsuke Miura, Sandra Garcet, Xuan Li, Inna Cueto, Charissa Salud-Gnilo, Norma Kunjravia, Kazuhiko Yamamura, Juana Gonzalez, Mika Murai-Yamamura, Darshna Rambhia …

The Journal of investigative dermatology 143(5) 832-841 2023年5月

PDE4 inhibition by difamilast regulates filaggrin and loricrin expression via keratinocyte proline-rich protein in human keratinocytes.

Gaku Tsuji, Akiko Hashimoto-Hachiya, Ayako Yumine, Masaki Takemura, Makiko Kido-Nakahara, Takamichi Ito, Kazuhiko Yamamura, Takeshi Nakahara

Journal of dermatological science 110(2) 61-68 2023年5月

Novel Therapeutic Targets for the Treatment of Atopic Dermatitis.

Gaku Tsuji, Kazuhiko Yamamura, Koji Kawamura, Makiko Kido-Nakahara, Takamichi Ito, Takeshi Nakahara

Biomedicines 11(5) 2023年4月27日

Identification of a functional DOCK8 gene polymorphism associated with atopic dermatitis.

Kazufumi Kunimura, Kazuhiko Yamamura, Takeshi Nakahara, Makiko Kido-Nakahara, Takehito Uruno, Yoshinori Fukui

Allergy 77(12) 3670-3672 2022年12月

The Dawn of a New Era in Atopic Dermatitis Treatment.

Kazuhiko Yamamura, Takeshi Nakahara

Journal of clinical medicine 11(20) 2022年10月18日

TH 2 cytokines and Staphylococcus aureus cooperatively induce atopic dermatitis-like transcriptomes.

Mika Murai-Yamamura, Sandra Garcet, Kazuhiko Yamamura, Juana Gonzalez, Shunsuke Miura, Xuan Li, Hong Hur, Emma Guttman-Yassky, James G Krueger

Allergy 76(11) 3534-3537 2021年11月

IL-36 and IL-17A Cooperatively Induce a Psoriasis-Like Gene Expression Response in Human Keratinocytes.

Shunsuke Miura, Sandra Garcet, Charissa Salud-Gnilo, Juana Gonzalez, Xuan Li, Mika Murai-Yamamura, Kazuhiko Yamamura, Darshna Rambhia, Norma Kunjravia, Emma Guttman-Yassky …

The Journal of investigative dermatology 141(8) 2086-2090 2021年8月

OVOL2-Mediated ZEB1 Downregulation May Prevent Promotion of Actinic Keratosis to Cutaneous Squamous Cell Carcinoma.

Maho Murata, Takamichi Ito, Yuka Tanaka, Kazuhiko Yamamura, Kazuhisa Furue, Masutaka Furue

Journal of clinical medicine 9(3) 2020年2月25日

Selective role of neurokinin B in IL-31-induced itch response in mice.

Daiji Sakata, Takehito Uruno, Keisuke Matsubara, Tsugunobu Andoh, Kazuhiko Yamamura, Yuki Magoshi, Kazufumi Kunimura, Yasuhisa Kamikaseda, Masutaka Furue, Yoshinori Fukui

The Journal of allergy and clinical immunology 144(4) 1130-1133 2019年10月

Serum squamous cell carcinoma antigen (SCCA)-2 correlates with clinical severity of pediatric atopic dermatitis in Ishigaki cohort.

Satoshi Takeuchi, Norihiro Furusyo, Junya Ono, Yoshinori Azuma, Masaki Takemura, Hitokazu Esaki, Kazuhiko Yamamura, Yasutaka Mitamura, Gaku Tsuji, Mari Kiyomatsu-Oda …

Journal of dermatological science 95(2) 70-75 2019年8月

Cyto/chemokine profile of in vitro scratched keratinocyte model: Implications of significant upregulation of CCL20, CXCL8 and IL36G in Koebner phenomenon.

Kazuhisa Furue, Takamichi Ito, Yuka Tanaka, Ayako Yumine, Akiko Hashimoto-Hachiya, Masaki Takemura, Maho Murata, Kazuhiko Yamamura, Gaku Tsuji, Masutaka Furue

Journal of dermatological science 94(1) 244-251 2019年4月

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye.

Tetsuya Sakurai, Takehito Uruno, Yuki Sugiura, Takaaki Tatsuguchi, Kazuhiko Yamamura, Miho Ushijima, Yuko Hattori, Mutsuko Kukimoto-Niino, Chiemi Mishima-Tsumagari, Mayuki Watanabe …

Science signaling 11(541) 2018年7月31日

Tryptophan photo-product FICZ upregulates AHR/MEK/ERK-mediated MMP1 expression: Implications in anti-fibrotic phototherapy.

Mika Murai, Kazuhiko Yamamura, Akiko Hashimoto-Hachiya, Gaku Tsuji, Masutaka Furue, Chikage Mitoma

Journal of dermatological science 91(1) 97-103 2018年7月

Highlighting Interleukin-36 Signalling in Plaque Psoriasis and Pustular Psoriasis.

Kazuhisa Furue, Kazuhiko Yamamura, Gaku Tsuji, Chikage Mitoma, Hiroshi Uchi, Takeshi Nakahara, Makiko Kido-Nakahara, Takafumi Kadono, Masutaka Furue

Acta dermato-venereologica 98(1) 5-13 2018年1月12日

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