2008
The effect of hydroxyapatite/gemosil nanocomposites on extracellular matrix patterning through the promotion of osteoblast self-organization
8th World Biomaterials Congress 2008
- ,
- ,
- ,
- ,
- ,
- ,
- Volume
- 2
- Number
- First page
- 611
- Last page
- Language
- Publishing type
- Research paper (international conference proceedings)
It was hypothesized that the hydroxyapatite(HAP)/GEMOSIL biomaterial could promote osteoblast (MC3T3) self-organization. This study using MC3T3 cell line demonstrated formation of trabecular bone-like extracellular matrix (ECM) on the material compared to unorganized ECM on the control (no-material). The study also initiated exploratory tests for the underlying mechanisms via gene analysis and proliferation assay.
- Link information
- ID information
-
- SCOPUS ID : 84869069348