安藤香奈絵 (Kanae Ando) - 論文

SARS-CoV-2-derived protein Orf9b enhances MARK2 activity via interaction with the autoinhibitory KA1 domain.

Daiki Homma, Sophia Jobien M Limlingan, Taro Saito, Kanae Ando

FEBS letters 598(19) 2385-2393 2024年10月最終著者責任著者

Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress

Lindsey D. Goodman, Isha Ralhan, Xin Li, Shenzhao Lu, Matthew J. Moulton, Ye-Jin Park, Pinghan Zhao, Oguz Kanca, Ziyaneh S. Ghaderpour Taleghani, Julie Jacquemyn …

Nature Neuroscience 27(10) 1918-1933 2024年8月26日査読有り

Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging.

Keiko Honda, Hiroo Takahashi, Saori Hata, Ruriko Abe, Takashi Saito, Takaomi C Saido, Hidenori Taru, Yuriko Sobu, Kanae Ando, Tohru Yamamoto …

Scientific reports 14(1) 18471-18471 2024年8月9日

Mark4 ablation attenuates pathological phenotypes in a mouse model of tauopathy

Grigorii Sultanakhmetov, Sophia Jobien M Limlingan, Aoi Fukuchi, Keisuke Tsuda, Hirokazu Suzuki, Iori Kato, Taro Saito, Adam Z Weitemier, Kanae Ando

Brain Communications 6(3) 2024年4月17日査読有り最終著者責任著者

Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β

Kanako Shinno, Yuri Miura, Koichi M. Iijima, Emiko Suzuki, Kanae Ando

eLife 2024年3月25日査読有り最終著者責任著者

Hippocampal hyperphosphorylated tau-induced deficiency is rescued by L-type calcium channel blockade

Chelsea A Crossley, Tamunotonye Omoluabi, Sarah E Torraville, Sarah Duraid, Aida Maziar, Zia Hasan, Vishaal Rajani, Kanae Ando, Johannes W Hell, Qi Yuan

Brain Communications 6(2) 2024年3月1日査読有り

Microtubule-affinity regulating kinase family members distinctively affect tau phosphorylation and promote its toxicity in a Drosophila model

Grigorii Sultanakhmetov, Iori Kato, Akiko Asada, Taro Saito, Kanae Ando

Genes to Cells 2024年2月査読有り最終著者責任著者

Dissecting the daily feeding pattern: Peripheral CLOCK/CYCLE generate the feeding/fasting episodes and neuronal molecular clocks synchronize them.

Akiko Maruko, Koichi M Iijima, Kanae Ando

iScience 26(11) 108164-108164 2023年11月17日査読有り責任著者

A cell-penetrating peptide derived from SARS-CoV-2 protein Orf9b allosterically inhibits MARK4 activity and mitigates tau toxicity.

Toshiya Oba, Daiki Homma, Sophia Jobien M Limlingan, Aoi Fukuchi, Akiko Asada, Taro Saito, Kanae Ando

Neurobiology of disease 188 106334-106334 2023年10月24日査読有り責任著者

5-Aminolevulinic acid bypasses mitochondrial complex I deficiency and corrects physiological dysfunctions in Drosophila

Naoko Nozawa, Marie Noguchi, Kanako Shinno, Taro Saito, Akiko Asada, Takuya Ishii, Kiwamu Takahashi, Masahiro Ishizuka, Kanae Ando

Human Molecular Genetics 32(16) 2611-2622 2023年6月26日査読有り最終著者責任著者

Valproic Acid-Induced Anxiety and Depression Behaviors are Ameliorated in p39 Cdk5 Activator-Deficient Mice

Miyuki Takahashi, Toshiyuki Takasugi, Arisa Kawakami, Ran Wei, Kanae Ando, Toshio Ohshima, Shin-ichi Hisanaga

Neurochemical Research 47(9) 2773-2779 2022年9月

5‐aminolevulinic acid and sodium ferrous citrate ameliorate muscle aging and extend healthspan in Drosophila

Naoko Nozawa, Marie Noguchi, Kanako Shinno, Maki Tajima, Shingo Aizawa, Taro Saito, Akiko Asada, Takuya Ishii, Masahiro Ishizuka, Koichi M. Iijima …

FEBS Open Bio 12(1) 295-305 2021年12月査読有り最終著者責任著者

Distinct phosphorylation profiles of tau in brains of patients with different tauopathies

Nastaran Samimi, Govinda Sharma, Taeko Kimura, Tomoyasu Matsubara, Anni Huo, Kurumi Chiba, Yuko Saito, Shigeo Murayama, Hiroyasu Akatsu, Yoshio Hashizume …

Neurobiology of Aging 108 72-79 2021年12月査読有り

Lemur tail kinase 1 (LMTK1) regulates the endosomal localization of β-secretase BACE1.

Keisuke Komaki, Tetsuya Takano, Yutaka Sato, Akiko Asada, Shikito Ikeda, Kaoru Yamada, Ran Wei, Anni Huo, Aoi Fukuchi, Taro Saito …

Journal of biochemistry 170(6) 729-738 2021年9月15日査読有り

Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo

Taro Saito, Tomoki Chiku, Mikiko Oka, Satoko Wada-Kakuda, Mika Nobuhara, Toshiya Oba, Kanako Shinno, Saori Abe, Akiko Asada, Akio Sumioka …

Human Molecular Genetics 30(21) 1955-1967 2021年6月17日査読有り責任著者

Hyperactive and impulsive behaviors of LMTK1 knockout mice

Miyuki Takahashi, Arika Sugiyama, Ran Wei, Shizuka Kobayashi, Kimiko Fukuda, Hironori Nishino, Roka Takahashi, Koji Tsutsumi, Ichiro Kita, Kanae Ando …

Scientific Reports 10(1) 2020年12月査読有り

Increasing neuronal glucose uptake attenuates brain aging and promotes lifespan under dietary restriction in Drosophila

Mikiko Oka, Emiko Suzuki, Akiko Asada, Taro Saito, Koichi M. Iijima, Kanae Ando

iScience (101979) 2020年12月査読有り責任著者

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.

Minghui Wang, Aiqun Li, Michiko Sekiya, Noam D Beckmann, Xiuming Quan, Nadine Schrode, Michael B Fernando, Alex Yu, Li Zhu, Jiqing Cao …

Neuron 2020年11月17日査読有り

Microtubule Affinity Regulating Kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration.

Toshiya Oba, Taro Saito, Akiko Asada, Sawako Shimizu, Koichi M Iijima, Kanae Ando

The Journal of biological chemistry 2020年10月5日査読有り責任著者

Tau Abnormalities and Autophagic Defects in Neurodegenerative Disorders; A Feed-forward Cycle

Nastaran Samimi, Akiko Asada, Kanae Ando