李影奕 (YING-YI LI) - マイポータル

基本情報

所属: 金沢大学システム生物学研究員

研究者番号: 70401940
J-GLOBAL ID: 202001014771980721
researchmap会員ID: R000000436

研究分野

論文

High-Throughput Screening of Antiviral Compounds Using a Recombinant Hepatitis B Virus and Identification of a Possible Infection Inhibitor, Skimmianine

Mika Yoshita, Masaya Funaki, Tetsuro Shimakami, Masaki Kakuya, Kazuhisa Murai, Saiho Sugimoto, Shotaro Kawase, Koji Matsumori, Taro Kawane, Tomoki Nishikawa …

Viruses 16(8) 1346-1346 2024年8月22日
Roles Played by DOCK11, a Guanine Nucleotide Exchange Factor, in HBV Entry and Persistence in Hepatocytes.

Ying-Yi Li, Kazuhisa Murai, Junyan Lyu, Masao Honda

Viruses 16(5) 2024年5月8日
BMP9-ID1 Pathway Attenuates N6-Methyladenosine Levels of CyclinD1 to Promote Cell Proliferation in Hepatocellular Carcinoma.

Han Chen, Mingming Zhang, Jianhao Li, Miao Liu, Dan Cao, Ying-Yi Li, Taro Yamashita, Kouki Nio, Hong Tang

International journal of molecular sciences 25(2) 2024年1月12日
Functional involvement of endothelial lipase in hepatitis B virus infection.

Takayoshi Shirasaki, Kazuhisa Murai, Atsuya Ishida, Kazuyuki Kuroki, Kazunori Kawaguchi, Ying Wang, Souma Yamanaka, Rio Yasukawa, Narumi Kawasaki, Ying-Yi Li …

Hepatology communications 7(9) 2023年9月1日
Super-Resolution Microscopy Analysis of Hepatitis B Viral cccDNA and Host Factors.

Phuong Thi Bich Doan, Kouki Nio, Tetsuro Shimakami, Kazuyuki Kuroki, Ying-Yi Li, Saiho Sugimoto, Hideo Takayama, Hikari Okada, Shuichi Kaneko, Masao Honda …

Viruses 15(5) 2023年5月16日
Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation

Ying-Yi Li, Kazuyuki Kuroki, Tetsuro Shimakami, Kazuhisa Murai, Kazunori Kawaguchi, Takayoshi Shirasaki, Kouki Nio, Saiho Sugimoto, Tomoki Nishikawa, Hikari Okada …

Cellular and Molecular Gastroenterology and Hepatology S2352-345X(22)00219-3.(3) 533-558 2022年10月査読有り
FOXM1 Is a Novel Molecular Target of AFP-Positive Hepatocellular Carcinoma Abrogated by Proteasome Inhibition.

Ru Li, Hikari Okada, Taro Yamashita, Kouki Nio, Han Chen, Yingyi Li, Tetsuro Shimakami, Hajime Takatori, Kuniaki Arai, Yoshio Sakai …

International journal of molecular sciences 23(15) 2022年7月27日
A single hepatitis B virus genome with a reporter allows the entire viral life cycle to be monitored in primary human hepatocytes.

Ariunaa Sumiyadorj, Kazuhisa Murai, Tetsuro Shimakami, Kazuyuki Kuroki, Tomoki Nishikawa, Masaki Kakuya, Atsumu Yamada, Ying Wang, Atsuya Ishida, Takayoshi Shirasaki …

Hepatology communications 2022年6月12日査読有り
BMP9-ID1 Signaling Activates HIF-1α and VEGFA Expression to Promote Tumor Angiogenesis in Hepatocellular Carcinoma

Han Chen, Kouki Nio, Hong Tang, Taro Yamashita, Hikari Okada, Yingyi Li, Phuong Thi Bich Doan, Ru Li, Junyan Lv, Yoshio Sakai …

International Journal of Molecular Sciences 23(3) 1475-1475 2022年1月27日
BMP9-ID1 signaling promotes EpCAM-positive cancer stem cell properties in hepatocellular carcinoma.

Han Chen, Kouki Nio, Taro Yamashita, Hikari Okada, Ru Li, Tsuyoshi Suda, Yingyi Li, Phuong Thi Bich Doan, Akihiro Seki, Hidetoshi Nakagawa …

Molecular oncology 15(8) 2203-2218 2021年8月
Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways.

Yang Li, Zhichao Xi, Xiaoqiong Chen, Shuangfan Cai, Chen Liang, Zhen Wang, Yingyi Li, Hongsheng Tan, Yuanzhi Lao, Hongxi Xu

Cell death & disease 9(5) 538-538 2018年5月1日
Pim-3 Regulates Stemness of Pancreatic Cancer Cells via Activating STAT3 Signaling Pathway

Ting Li, Zhen Wang, Yi-feng Hou, Ying-yi Li

JOURNAL OF CANCER 8(9) 1530-1541 2017年査読有り
Bufalin suppresses cancer stem-like cells in gemcitabine-resistant pancreatic cancer cells via Hedgehog signaling

Haiyong Wang, Zhouyu Ning, Yingyi Li, Xiaoyan Zhu, Zhiqiang Meng

MOLECULAR MEDICINE REPORTS 14(3) 1907-1914 2016年9月査読有り
Pim-3 contributes to radioresistance through regulation of the cell cycle and DNA damage repair in pancreatic cancer cells

Xiang-Yuan Chen, Zhen Wang, Bei Li, Ying-Jian Zhang, Ying-Yi Li

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 473(1) 296-302 2016年4月査読有り
KDM4B promotes epithelial-mesenchymal transition through up-regulation of ZEB1 in pancreatic cancer

Shuo Li, Linlin Wu, Qingbing Wang, Yingyi Li, Xiaolin Wang

ACTA BIOCHIMICA ET BIOPHYSICA SINICA 47(12) 997-1004 2015年12月査読有り
miR-33a suppresses the nuclear translocation of beta-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells

Chen Liang, Zhen Wang, Ying-Yi Li, Bao-Hua Yu, Fei Zhang, Hong-Yu Li

TUMOR BIOLOGY 36(12) 9395-9403 2015年12月査読有り
FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7

Yu-Pan Bai, Kun Shang, Huan Chen, Fei Ding, Zhen Wang, Chen Liang, Ye Xu, Meng-Hong Sun, Ying-yi Li

CANCER SCIENCE 106(10) 1278-1287 2015年10月査読有り
Orthotopic inflammation-related pancreatic carcinogenesis in a wild-type mouse induced by combined application of caerulein and dimethylbenzanthracene

Chen Liang, Zhen Wang, Li Wu, Chen Wang, Bao-Hua Yu, Xiu-Zhong Yao, Xiao-Lin Wang, Ying-Yi Li

TUMOR BIOLOGY 36(10) 7557-7568 2015年9月査読有り
Dynamic contrast-enhanced (DCE) MRI assessment of microvascular characteristics in the murine orthotopic pancreatic cancer model

Li Wu, Peng Lv, Haitao Zhang, Caixia Fu, Xiuzhong Yao, Chen Wang, Mengsu Zeng, Yingyi Li, Xiaolin Wang

MAGNETIC RESONANCE IMAGING 33(6) 737-760 2015年7月査読有り
MicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine

Chen Liang, Xian-Jun Yu, Xiao-Zhong Guo, Meng-Hong Sun, Zhen Wang, Yao Song, Quan-Xing Ni, Hong-Yu Li, Naofumi Mukaida, Ying-Yi Li

ONCOTARGET 6(16) 14440-14455 2015年6月査読有り

もっとみる

講演・口頭発表等

HBV persistence – DOCK11 promotes HBV utilizing a retrograde trafficking route via the TGN to avoid lysosomal degradation.

2023年9月20日
DOCK11 might be a candidate druggable target for HBV cure

JDDW 2021年11月4日
Blockade of Pim-3/ASS1 axis confers tumor cell response to arginine deprivation in pancreatic cancer

２０１８年中国膵臓病および消化病・消化内視鏡学会招待有り

主要な所属学協会

2021年1月 - 現在

日本肝臓学会

主要な共同研究・競争的資金等の研究課題

DOCK11ノックダウンによりcccDNA排除の新規抗HBV治療応用への基礎研究

日本学術振興会科学研究費助成事業基盤研究(C) 基盤研究(C) 2018年4月 - 2021年3月

李影奕, 本多政夫