Chiharu Tsuji - My portal - researchmap

Profile Information

Researcher number: 00523490
J-GLOBAL ID: 201801000036029135
researchmap Member ID: B000326531

Research Areas

1

Life sciences / Molecular biology /

Papers

56

Infant Stimulation Induced a Rapid Increase in Maternal Salivary Oxytocin.

Kana Minami, Teruko Yuhi, Haruhiro Higashida, Shigeru Yokoyama, Takahiro Tsuji, Chiharu Tsuji

Brain sciences, 12(9), Sep 15, 2022
Early-onset of social communication and locomotion activity in F2 pups of a valproic acid-induced mouse model of autism.

Chiharu Tsuji, Kazumi Furuhara, Ryuko Mizutani, Kana Minami, Pinyue Fu, Jing Zhong, Haruhiro Higashida, Shigeru Yokoyama, Takahiro Tsuji

Neuroscience letters, 788 136827-136827, Aug 6, 2022
Oxytocin Dynamics in the Body and Brain Regulated by the Receptor for Advanced Glycation End-Products, CD38, CD157, and Nicotinamide Riboside

Haruhiro Higashida, Kazumi Furuhara, Olga Lopatina, Maria Gerasimenko, Osamu Hori, Tsuyoshi Hattori, Yasuhiko Hayashi, Stanislav M. Cherepanov, Anna A. Shabalova, Alla B. Salmina, Kana Minami, Teruko Yuhi, Chiharu Tsuji, PinYue Fu, Zhongyu Liu, Shuxin Luo, Anpei Zhang, Shigeru Yokoyama, Satoshi Shuto, Mizuki Watanabe, Koichi Fujiwara, Sei-ichi Munesue, Ai Harashima, Yasuhiko Yamamoto

Frontiers in Neuroscience, 16, Jul 7, 2022
Oral Supplementation with L-Carnosine Attenuates Social Recognition Deficits in CD157KO Mice via Oxytocin Release.

Takahiro Tsuji, Kazumi Furuhara, Maria Gerasimenko, Anna Shabalova, Stanislav M Cherepanov, Kana Minami, Haruhiro Higashida, Chiharu Tsuji

Nutrients, 14(4), Feb 14, 2022
Oxytocin administration modulates the complex type of ultrasonic vocalisation of mice pups prenatally exposed to valproic acid.

Takahiro Tsuji, Ryuko Mizutani, Kana Minami, Kazumi Furuhara, Tomoaki Fujisaku, Fu Pinyue, Zhong Jing, Chiharu Tsuji

Neuroscience letters, 135985-135985, May 25, 2021
Experimental Attempt on Walking Behavior and Stress Assessment in a Completely Darkened Tunnel

Miho Seike, Nobuyoshi Kawabata, Masato Hasegawa, Chiharu Tsuji, Haruhiro Higashida, Teruko Yuhi

Infrastructures, 6(5) 75-75, May 13, 2021
Oxytocin ameliorates impaired social behavior in a Chd8 haploinsufficiency mouse model of autism.

Stanislav M Cherepanov, Maria Gerasimenko, Teruko Yuhi, Kazumi Furuhara, Chiharu Tsuji, Shigeru Yokoyama, Keiichi I Nakayama, Masaaki Nishiyama, Haruhiro Higashida

BMC neuroscience, 22(1) 32-32, May 1, 2021
Participatory Art Activities Increase Salivary Oxytocin Secretion of ASD Children.

Sanae Tanaka, Aiko Komagome, Aya Iguchi-Sherry, Akiko Nagasaka, Teruko Yuhi, Haruhiro Higashida, Maki Rooksby, Mitsuru Kikuchi, Oko Arai, Kana Minami, Takahiro Tsuji, Chiharu Tsuji

Brain sciences, 10(10), Sep 27, 2020 Peer-reviewed
Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder.

Maria Gerasimenko, Stanislav M Cherepanov, Kazumi Furuhara, Olga Lopatina, Alla B Salmina, Anna A Shabalova, Chiharu Tsuji, Shigeru Yokoyama, Katsuhiko Ishihara, Charles Brenner, Haruhiro Higashida

Scientific reports, 10(1) 10035-10035, Jun 22, 2020 Peer-reviewed
Oxytocin induced epithelium-mesenchimal transition through Rho-ROCK pathway in ARPE-19 cells, a human retinal pigmental cell line.

Takahiro Tsuji, Masaru Inatani, Chiharu Tsuji, Stanislav M Cheranov, Kazuaki Kadonosono

Tissue & cell, 64 101328-101328, Jun, 2020 Peer-reviewed
Oxytocin ameliorates maternal separation-induced ultrasonic vocalisation calls in mouse pups prenatally exposed to valproic acid.

Chiharu Tsuji, Tomoaki Fujisaku, Takahiro Tsuji

Journal of neuroendocrinology, 32(4) e12850, Apr, 2020 Peer-reviewed
Oxytocin and CD38 in the paraventricular nucleus play a critical role in paternal aggression in mice.

Anna A Shabalova, Mingkun Liang, Jing Zhong, Zhiqi Huang, Chiharu Tsuji, Natalia A Shnayder, Olga Lopatina, Alla B Salmina, Hiroshi Okamoto, Yasuhiko Yamamoto, Zeng-Guo Zhong, Shigeru Yokoyama, Haruhiro Higashida

Hormones and behavior, 120 104695-104695, Apr, 2020 Peer-reviewed
A monoclonal antibody raised against a synthetic oxytocin peptide stains mouse hypothalamic neurones

Yuji Kogami, Takahiro Tsuji, Chiharu Tsuji, Shigeru Yokoyama, Kazumi Furuhara, Olga Lopatina, Anna Shabalova, Alla B. Salmina, Yumi Watanabe, Tsuyoshi Hattori, Katsuhiko Nishimori, Kota Kodama, Haruhiro Higashida

JOURNAL OF NEUROENDOCRINOLOGY, 32(4) e12815, Apr, 2020 Peer-reviewed
One Single Nucleotide Polymorphism of the TRPM2 Channel Gene Identified as a Risk Factor in Bipolar Disorder Associates with Autism Spectrum Disorder in a Japanese Population.

Naila Al Mahmuda, Shigeru Yokoyama, Toshio Munesue, Kenshi Hayashi, Kunimasa Yagi, Chiharu Tsuji, Haruhiro Higashida

Diseases (Basel, Switzerland), 8(1), Feb 7, 2020 Peer-reviewed
CD38, CD157, and RAGE as Molecular Determinants for Social Behavior

Haruhiro Higashida, Minako Hashii, Yukie Tanaka, Shigeru Matsukawa, Yoshihiro Higuchi, Ryosuke Gabata, Makoto Tsubomoto, Noriko Seishima, Mitsuyo Teramachi, Taiki Kamijima, Tsuyoshi Hattori, Osamu Hori, Chiharu Tsuji, Stanislav M. Cherepanov, Anna A. Shabalova, Maria Gerasimenko, Kana Minami, Shigeru Yokoyama, Sei-ichi Munesue, Ai Harashima, Yasuhiko Yamamoto, Alla B. Salmina, Olga Lopatina

CELLS, 9(1), Jan, 2020 Peer-reviewed
Coding of odors in the anterior olfactory nucleus.

Takahiro Tsuji, Chiharu Tsuji, Maja Lozic, Mike Ludwig, Gareth Leng

Physiological reports, 7(22) e14284, Nov, 2019 Peer-reviewed
CD38 in the Nucleus Accumbens is Critical in Paternal Behavior in Mice

Akther, Shirin, Zhong, Jing, Liang, Mingkun, Cherepanov, Stanislav M, Lopatina, Olga, Salmina, Alla B, Tsuji, Chiharu, Tsuji, Takahiro, Yamamoto, Yasuhiko, Yokoyama, Shegeru, Higashida, Haruhiro

6(4) 81-84, Nov, 2018
The Contributions of Cd38 and Cd157 Gene Deletion in Neurobehavioral Outcomes

Authors: Lopatina, Olga L, Kasai, Satoka, Cherepanov, Stanislav M, Furuhara, Kazumi, Yoshihara, Toru, Shabalova, Anna A, Gerasimenko, Maria N, Tsuji, Chiharu, Yokoyama, Shigeru, Higashida, Haruhiro, Salmina, Alla B

Messenger, 6(1-2) 99-104, Nov, 2018
Maternal Behavior of CD38 Knockout Dams is Improved by Social Support

Chiharu Tsuji

Messenger, 6(1-2) 76-80, Nov, 2018
TRPM2, a New Player, in Cyclic ADP-Ribose/CD38-Dependent Oxytocin Release in the Hypothalamus

Tsuji, Takahiro, Liang, Mingkun, Lopatina, Olga, Yuhi, Teruko, Tsuji, Chiharu, Zhong, Jing, Akther, Shirin, Nishimura, Tomoko, Amina, Sarwat, Liu, Hong-Xiang, Hashii, Minako, Furuhara, Kazumi, Yamamoto, Yasuhiko, Yokoyama, Shigeru, Higashida, Haruhiro

Messenger, 6(1-2) 71-75, Nov, 2018

More

Misc.

12

ASDのある児童生徒に対するアートワークショップの効果思春期の自己理解に及ぼす影響と生理的指標の検討

田中早苗, 辻知陽, ROCKSBY Maki, IGUCHI SHERRY Aya

日本発達心理学会大会プログラム(CD-ROM), 30th ROMBUNNO.PS1‐52, 2019
Experimental Investigation Regarding Evacuation Speed and Stress Assessment by Oxytocin Concentration Measurement in Full-Scale Tunnel

SEIKE Miho, TSUJI Chiharu, KAWABATA Nobuyoshi, Hasegawa Masato, HIGASHIDA Haruhiro, YUHI Mitsuko

The Proceedings of Mechanical Engineering Congress, Japan, 2018 S0540301, 2018
Effects of lateral olfactory tract stimulation on Fos immunoreactivity in vasopressin neurones of the rat piriform cortex

C. Tsuji, T. Tsuji, A. Allchorne, G. Leng, M. Ludwig

JOURNAL OF NEUROENDOCRINOLOGY, 29(11), Nov, 2017
Erratum to: Effects of lateral olfactory tract stimulation on Fos immunoreactivity in vasopressin neurones of the rat piriform cortex (Journal of Neuroendocrinology, (2017), 29, 11, (e12531), 10.1111/jne.12531)

C. Tsuji, T. Tsuji, A. Allchorne, G. Leng, M. Ludwig

Journal of Neuroendocrinology, 30, Nov 1, 2017
Oxytocin and social behavior : Autism spectrum disorder revisited from oxytocin secretion mechanism

東田陽博, 横山茂, 由比光子, 辻知陽, 廣澤徹, 菊知充, 橋本隆紀, 三邉義雄

月刊精神科, 30(1) 75-80, Jan, 2017
Oxytocin and social behavior : Autism spectrum disorder revisited from oxytocin secretion mechanism

東田陽博, 横山茂, 由比光子, 辻知陽, 廣澤徹, 菊知充, 橋本隆紀, 三邉義雄

精神科 = Psychiatry, 30(1) 75-80, Jan, 2017
マウス脳内のEct2の発現解析

吉田康真, 辻隆宏, イスラム・モハマド・シャハル, 東田知陽, 小泉恵太, 堂本光子, 東田陽博

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 83回・33回 4P-1039, Dec, 2010
A ROLE OF HOMEOSTASIS BETWEEN G- AND F-ACTIN IN CELLULAR ACTIN POLYMER RESTORATION MECHANISMS INVOLVING A Rho EFFECTER, mDia1

Naoki Watanabe, Chiharu Higashida, Hiroaki Mizuno

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 349-349, 2009
Rapid activation of mDia1 to restore cellular actin polymers regulated by G-actin

Chiharu Higashida, Shiro Suetsugu, Shuh Narumiya, Naoki Watanabe

JOURNAL OF PHARMACOLOGICAL SCIENCES, 106 161P-161P, 2008
単分子スペックル顕微鏡によるアクチン生化学の一分子イメージング

東田知陽, 三好拓志, 渡邊直樹

蛋白質核酸酵素, 50(11) 1436-1442, Sep, 2005
Evidence of constitutive actin filament severing in lamellipodia

Takushi Miyoshi, Chiharu Higashida, Naoki Watanabe

CELL STRUCTURE AND FUNCTION, 30 11-11, Jun, 2005
Actin polymerization-driven directional movement of mDial as revealed by single-molecule speckle microscopy in living cells

Chiharu Higashida, Shuh Narumiya, Naoki Watanabe

CELL STRUCTURE AND FUNCTION, 29 23-23, May, 2004

Presentations

18

Deficit of maternal behavior of CD38 KO autism model mouse induced by the isolation stress is improved by the social support.

Takahiro Tsuji, Shigeru Yokoyama, Yasuhiko Yamamoto, Haruhiro Higashida, Chiharu Tsuji

Feb 7, 2019
The deficit of pup USV calls in the valproic-acid induced mouse model of autism.

Tomoaki Fujisaku, Chiharu Tsuji, Yoshinari Nasu, Anna A. Shabalova, Stanislav M. Cherepanov, Shigeru Yokoyama, Kazumi Furuhara, Sodoe Saika, Takahiro Tsuji

Feb 7, 2019
Establishing the female social behavioral paradigm to detect social deficit in the valproic acid-induced mouse model of autism.

Feb 7, 2019
Establishing the biomarkers to assess the effect of participatory art work shop on autistic children.

Chiharu Tsuji, Maki Rooksby, Aya Iguchi-Sherry, Teruko Yuhi, Kana Minami, Haruhiro Higashida, Sanae Tanaka

Feb 7, 2019
Establishing the verification methods to assess the effect of art workshop on autistic children.

Sanae Tanaka, Aya Iguchi Sherry, Maki Rooksby, Teruko Yuhi, Kana Minami, Haruhiro Higashida, Chiharu Tsuji

Jan 15, 2019
Carnosine attenuates the social deficit of CD157KO mouse model of autism

Chiharu Tsuji, Kazumi Furuhara, Maria Gerasimenko, Kana Minami, Shigeru Yokoyama, Haruhiro Higashida, Takahiro Tsuji

Jan 15, 2019
Maternal behavior of CD38 KO autism model mouse dam is improved by social support

Takahiro Tsuji, Shigeru Yokoyama, Yasuhiko Yamamoto, Haruhiro Higashida, Chiharu Tsuji

Jan 15, 2019
Analysis of pup USV calls in the valproic-acid induced mouse model of autism.

Tomoaki Fujisaku, Chiharu Tsuji, Yoshinari Nasu, Anna A. Shabalova, Stanislav M. Cherepanov, Shigeru Yokoyama, Takahiro Tsuji

Jan 15, 2019
Analysis of ultrasonic vocalization in the valproic-acid induced female mouse model of autism.

Pinyue Fu, Jing Zhong, Takahiro Tsuji, Shunki Yamaguchi, Anna A. Shabalova, Maria Gerasimenko, Stanislav M. Cherepanov, Shegeru Yokoyama, Chiharu Tsuji

Jan 15, 2019
Analysis of paternal aggression in CD38 knockout autism model mice.

Anna A. Shabalova, Mingkum Liang, Jing Zhong, Chiharu Tsuji, Yasuhiko Yamamoto, Shigeru Yokoyama, Haruhiro Higashida

Jan 15, 2019
引きこもり防止対策として社会抵抗性を高めるアート療育の応用可能性を検証するプロジェクト

辻知陽

COI2021会議, Dec, 2018
Analysis of USV calls induced ouse model of autism.

Tomoaki Fujisaku, Chiharu Tsuji, Takahiro Tsuji

Sep 6, 2018
Maternal behavior of CD38 KO dam is improved by social support.

Takahiro Tsuji, Haruhiro Higashida, Chiharu Tsuji

Sep 6, 2018
実大トンネルでの避難速度とオキシトシン濃度計測によるストレス評価に関する実験的研究

日本機械学会2018年度年次大会, Sep, 2018
A preliminary report of NAD precursors on social behaviors in mice.

Shabalova, A. A, Zhong, J, Mingkum, L, Tsuji, C, Yokoyama, S, Higashida, H

Sep, 2017
Effects of lateral olfactory tract stimulation on brain Fos immunoreactivity in vasopressin neurons of the rat piriform cortex.

Chiharu Tsuji, Takahiro Tsuji, Andrew Allchorn, Gareth Leng, Mike Ludwig

2017
Vasopressin-expressing neurons in piriform cortex.

Chiharu Tsuji

Aug 28, 2016
Immediate early gene expression in the olfactory system induced by lateral olfactory tract stimulation.

Chiharu Tsuji

Jul 29, 2016

Research Projects

5

父親になる男性の養育ホルモン（オキシトシン）の変動およびその役割の解明

科学研究費助成事業基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2023

南香奈, 辻知陽, 東田陽博, 鏡真美
Physiological role of arginine vasopressin released from RGCs on circadian rhythm and psychiatry function

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022
社会性ホルモンバソプレシンの嗅覚系神経回路の解明

科学研究費助成事業基盤研究(C), 日本学術振興会, Apr, 2018 - Mar, 2021

辻知陽, 辻隆宏
社会認識関連神経ペプチド－オキシトシン－の脳内分泌機構の解析

科学研究費助成事業特別研究員奨励費, 日本学術振興会, Apr, 2013 - Mar, 2015

辻知陽
単分子スペックル法によるアクチン重合モーター、mDia1の時空間的制御の解明

科学研究費助成事業特別研究員奨励費, 日本学術振興会, 2006 - 2008

東田知陽