論文

査読有り 国際誌
2018年3月15日

Prevalence of posterior staphyloma and factors associated with its shape in the Japanese population.

Scientific reports
  • Shogo Numa
  • Kenji Yamashiro
  • Tomotaka Wakazono
  • Munemitsu Yoshikawa
  • Masahiro Miyake
  • Hideo Nakanishi
  • Akio Oishi
  • Yasuharu Tabara
  • Fumihiko Matsuda
  • Nagahisa Yoshimura
  • Akitaka Tsujikawa
  • 全て表示

8
1
開始ページ
4594
終了ページ
4594
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1038/s41598-018-22759-y

Myopia is increasing rapidly worldwide. We performed a cross-sectional study to investigate the prevalence of posterior staphyloma, a complication of myopia, and its shape characteristics in relation to age, sex, and axial length (AL) in a Japanese community-based cohort. The right eyes of 3748 participants who underwent fundus photography and optical coherence tomography (OCT) examination were evaluated. Posterior staphyloma prevalence was evaluated using fundus photographs and OCT images. Furthermore, fundus shapes were analyzed by measuring local fundus curvatures on 6 mm cross-line OCT images at intervals of 1 µm. The mean and variance of the curvatures were calculated to represent the fundus shape of each eye for investigation of the relationship between fundus curvature and age, sex, and AL. Seventy-seven eyes (2.05%) had posterior staphyloma. The mean and variance of the fundus curvatures were significantly greater in women than in men and became greater with age, suggesting that the shape of the staphyloma was steeper and less smooth in women and elderly subjects. AL and mean curvature showed a significant correlation (P = 2 × 10-16, R = 0.480), which was significantly affected by age (P < 2 × 10-16). Quantitative analysis of fundus shapes was useful for statistical analysis of posterior staphyloma in relation to age, sex, and AL.

リンク情報
DOI
https://doi.org/10.1038/s41598-018-22759-y
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29545631
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854606
ID情報
  • DOI : 10.1038/s41598-018-22759-y
  • PubMed ID : 29545631
  • PubMed Central 記事ID : PMC5854606

エクスポート
BibTeX RIS