論文

2024年2月12日

Strong Diagnostic Performance of Single Energy 256-row Multidetector Computed Tomography with Deep Learning Image Reconstruction in the Assessment of Myocardial Fibrosis.

Internal medicine (Tokyo, Japan)
  • Shuhei Aoki
  • Hiroyuki Takaoka
  • Joji Ota
  • Tomonori Kanaeda
  • Takayuki Sakai
  • Koji Matsumoto
  • Yoshitada Noguchi
  • Yusei Nishikawa
  • Satomi Yashima
  • Katsuya Suzuki
  • Kazuki Yoshida
  • Makiko Kinoshita
  • Noriko Suzuki-Eguchi
  • Haruka Sasaki
  • Yoshio Kobayashi
  • 全て表示

記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2169/internalmedicine.2615-23

Objective Although magnetic resonance imaging (MRI) is the gold standard for evaluating abnormal myocardial fibrosis and extracellular volume (ECV) of the left ventricular myocardium (LVM), a similar evaluation has recently become possible using computed tomography (CT). In this study, we investigated the diagnostic accuracy of a new 256-row multidetector CT with a low tube-voltage single energy scan and deep-learning-image reconstruction (DLIR) in detecting abnormal late enhancement (LE) in LVM. Methods We evaluated the diagnostic performance of CT for detecting LE in LVM and compared the results with those of MRI as a reference. We also measured the ECV of the LVM on CT and compared the results with those on MRI. Patients or Materials We analyzed 50 consecutive patients who underwent cardiac CT, including a late-phase scan and MRI, within three months of suspected cardiomyopathy. All patients underwent 256-slice CT (Revolution CT Apex; GE Healthcare) with a low tube-voltage (70 kV) single energy scan and DLIR for a late-phase scan. Results In patient- and segment-based analyses, the sensitivity, specificity, and accuracy of detection of LE on CT were 94% and 85%, 100% and 95%, and 96% and 93%, respectively. The ECV of LVM per patient on CT and MRI was 33.0% ±6.2% and 35.9% ±6.1%, respectively. These findings were extremely strongly correlated, with a correlation coefficient of 0.87 (p <0.0001). The effective radiation dose on late-phase scanning was 2.4±0.9 mSv. Conclusion The diagnostic performance of 256-row multislice CT with a low tube voltage and DLIR for detecting LE and measuring ECV in LVM is credible.

リンク情報
DOI
https://doi.org/10.2169/internalmedicine.2615-23
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/38346744
ID情報
  • DOI : 10.2169/internalmedicine.2615-23
  • PubMed ID : 38346744

エクスポート
BibTeX RIS