論文

2010年

PCaPs, possible regulators of PtdInsP signals on plasma membrane

Plant Signaling and Behavior
  • Mariko Kato
  • ,
  • Nahoko Nagasaki-Takeuchi
  • ,
  • Yuki Ide
  • ,
  • Rie Tomioka
  • ,
  • Masayoshi Maeshima

5
7
開始ページ
848
終了ページ
850
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.4161/psb.5.7.11825
出版者・発行元
Landes Bioscience

In plants, Ca2+, phosphatidylinositol phosphates (PtdInsPs) and inositol phosphates are major components of intracellular signaling. Several kinds of proteins and enzymes, such as calmodulin (CaM), protein kinase, protein phosphatase, and the Ca2+ channel, mediate the signaling. Two new Ca2+-binding proteins were identified from Arabidopsis thaliana and named PCaP1 and PCaP2 [plasma membrane (PM)-associated Ca2+(cation)-binding protein 1 and 2]. PCaP1 has an intrinsically disordered region in the central and C-terminal parts. The PCaP1 gene is expressed in most tissues and the PCaP2 gene is expressed predominantly in root hairs and pollen tubes. We recently demonstrated that these proteins are N-myristoylated, stably anchored in the PM, and are bound with phosphatidylinositol phosphates, especially PtdInsP2s. Here we propose a model for the switching mechanism of Ca2+-signaling mediated by PtdInsPs. Ca2+ forms a complex with CaM (Ca2+-CaM) when there is an increase in the cytosol free Ca2+. The binding of PCaPs with Ca2+-CaM causes PCaPs to release PtdInsPs. Until the release of PtdInsPs, the signaling is kept in the resting state. © 2010 Landes Bioscience.

リンク情報
DOI
https://doi.org/10.4161/psb.5.7.11825
ID情報
  • DOI : 10.4161/psb.5.7.11825
  • ISSN : 1559-2324
  • ISSN : 1559-2316
  • SCOPUS ID : 77957003818

エクスポート
BibTeX RIS