<title>Abstract</title>It is conjectured that the central quotient of any irreducible Artin–Tits group is either virtually cyclic or acylindrically hyperbolic. We prove this conjecture for Artin–Tits groups that are known to be CAT(0) groups by a result of Brady and McCammond, that is, Artin–Tits groups associated with graphs having no 3-cycles and Artin–Tits groups of almost large type associated with graphs admitting appropriate directions. In particular, the latter family contains Artin–Tits groups of large type associated with cones over square-free bipartite graphs.