論文

査読有り
2017年4月

Energy metabolism differs between sleep stages and begins to increase prior to awakening

METABOLISM-CLINICAL AND EXPERIMENTAL
  • Momoko Kayaba
  • ,
  • Insung Park
  • ,
  • Kaito Iwayama
  • ,
  • Yumi Seya
  • ,
  • Hitomi Ogata
  • ,
  • Katsuhiko Yajima
  • ,
  • Makoto Satoh
  • ,
  • Kumpei Tokuyama

69
開始ページ
14
終了ページ
23
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.metabol.2016.12.016
出版者・発行元
W B SAUNDERS CO-ELSEVIER INC

Purpose. Human sleep is generally consolidated into a single prolonged period, and its metabolic consequence is to impose an extended period of fasting. Changes in sleep stage and homeostatic sleep drive following sleep onset may affect sleeping metabolic rate through cross talk between the mechanisms controlling energy metabolism and sleep. The purpose of this study was to isolate the effects of sleep stage and time after sleep onset on sleeping metabolic rate.
Methods. The sleeping metabolic rate of 29 healthy adults was measured using whole room indirect calorimetry, during which polysomnographic recording of sleep was performed. The effects of sleep stage and time after sleep onset on sleeping metabolic rate were evaluated using a semi-parametric regression analysis. A parametric analysis was used for the effect of sleep stage and a non-parametric analysis was used for the effect of time.
Results. Energy expenditure differed significantly between sleep stages: wake after sleep onset (WASO) > stage 2, slow wave sleep (SWS), and REM; stage 1 > stage 2 and SWS; and REM > SWS. Similarly, carbohydrate oxidation differed significantly between sleep stages: WASO > stage 2 and SWS; and stage 1 > SWS. Energy expenditure and carbohydrate oxidation decreased during the first half of sleep followed by an increase during the second half of sleep.
Conclusions. This study identified characteristic phenotypes in energy expenditure and carbohydrate oxidation indicating that sleeping metabolic rate differs between sleep stages. (C) 2017 Elsevier Inc. All rights reserved.

Web of Science ® 被引用回数 : 13

リンク情報
DOI
https://doi.org/10.1016/j.metabol.2016.12.016
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28285643
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000397697800002&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.metabol.2016.12.016
  • ISSN : 0026-0495
  • eISSN : 1532-8600
  • PubMed ID : 28285643
  • Web of Science ID : WOS:000397697800002

エクスポート
BibTeX RIS