論文

査読有り
2020年9月12日

Skipping Breakfast for 6 Days Delayed the Circadian Rhythm of the Body Temperature without Altering Clock Gene Expression in Human Leukocytes

Nutrients
  • Hitomi Ogata
  • ,
  • Masaki Horie
  • ,
  • Momoko Kayaba
  • ,
  • Yoshiaki Tanaka
  • ,
  • Akira Ando
  • ,
  • Insung Park
  • ,
  • Simeng Zhang
  • ,
  • Katsuhiko Yajima
  • ,
  • Jun-ichi Shoda
  • ,
  • Naomi Omi
  • ,
  • Miki Kaneko
  • ,
  • Ken Kiyono
  • ,
  • Makoto Satoh
  • ,
  • Kumpei Tokuyama

12
9
開始ページ
2797
終了ページ
2797
記述言語
掲載種別
研究論文(学術雑誌)
DOI
10.3390/nu12092797
出版者・発行元
MDPI AG

Breakfast is often described as “the most important meal of the day” and human studies have revealed that post-prandial responses are dependent on meal timing, but little is known of the effects of meal timing per se on human circadian rhythms. We evaluated the effects of skipping breakfast for 6 days on core body temperature, dim light melatonin onset, heart rate variability, and clock gene expression in 10 healthy young men, with a repeated-measures design. Subjects were provided an isocaloric diet three times daily (3M) or two times daily (2M, i.e., breakfast skipping condition) over 6 days. Compared with the 3M condition, the diurnal rhythm of the core body temperature in the 2M condition was delayed by 42.0 ± 16.2 min (p = 0.038). On the other hand, dim light melatonin onset, heart rate variability, and clock gene expression were not affected in the 2M condition. Skipping breakfast for 6 days caused a phase delay in the core body temperature in healthy young men, even though the sleep–wake cycle remained unchanged. Chronic effects of skipping breakfast on circadian rhythms remain to be studied.

リンク情報
DOI
https://doi.org/10.3390/nu12092797
URL
https://www.mdpi.com/2072-6643/12/9/2797/pdf
ID情報
  • DOI : 10.3390/nu12092797
  • eISSN : 2072-6643

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