asakawa kazuhide Last updated: Jun 13, 2019 at 15:46
Research Interests
ALS(41) ,
reticulospinal neuron(1) ,
motoneuron(4) ,
brainstem(11) ,
locomotion(15) ,
escape behavior(1) ,
ethology(46) ,
microtubule(28) ,
spinal cord(30) ,
embryogenesis(20) ,
lectin(38) ,
zebrafish(50) Academic & Professional Experience
2019
-
Today
Associate professor, Tokyo Medical University
2009
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2019
Assistant professor, National Institute of Genetics
2006
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2009
JSPS Research Fellow （PD）, National Institute of Genetics
2004
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2006
Project Researcher, National Institute of Genetics
2002
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2004
Research Fellow, Cancer Research UK
Education
1997
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2002
Department of Biological Sciences, Graduate School of Science, The University of Tokyo
1993
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1997
Biology, Faculty of Science, Kyoto University
Awards & Honors
Dec 2017
SERIKA FUND, SERIKA FUND
2007
Best Poster at 5th European Zebrafish Genetics and Development Meeting
Published Papers
Asakawa K, Kawakami K
Cell reports 24(6) 1562-1572 Aug 2018 [Refereed]
Ohki Y, Wenninger-Weinzierl A, Hruscha A, Asakawa K, Kawakami K, Haass C, Edbauer D, Schmid B
Molecular neurodegeneration 12(1) 6 Jan 2017 [Refereed]
Kamezaki A, Sato F, Aoki K, Asakawa K, Kawakami K, Matsuzaki F, Sehara-Fujisawa A
Scientific reports 6 28873 Jul 2016 [Refereed]
Kawakami K, Asakawa K, Hibi M, Itoh M, Muto A, Wada H
Advances in genetics 95 65-87 2016 [Refereed]
Kawakami K, Asakawa K, Muto A, Wada H
Methods in cell biology 135 19-37 2016 [Refereed]
Ogino K, Low SE, Yamada K, Saint-Amant L, Zhou W, Muto A, Asakawa K, Nakai J, Kawakami K, Kuwada JY, Hirata H
Proceedings of the National Academy of Sciences of the United States of America 112 2859-2864 Mar 2015 [Refereed]
Takeuchi M, Matsuda K, Yamaguchi S, Asakawa K, Miyasaka N, Lal P, Yoshihara Y, Koga A, Kawakami K, Shimizu T, Hibi M
Developmental biology Oct 2014 [Refereed]
Kwon HB, Fukuhara S, Asakawa K, Ando K, Kashiwada T, Kawakami K, Hibi M, Kwon YG, Kim KW, Alitalo K, Mochizuki N
Development (Cambridge, England) 140 4081-4090 Oct 2013 [Refereed]
Wada H, Ghysen A, Asakawa K, Abe G, Ishitani T, Kawakami K
Current biology : CB 23(16) 1559-1565 Jul 2013 [Refereed]
Kishimoto N, Asakawa K, Madelaine R, Blader P, Kawakami K, Sawamoto K
Nature neuroscience 16(7) 884-888 May 2013 [Refereed]
Yamanaka I, Miki M, Asakawa K, Kawakami K, Oda Y, Hirata H
Genes to cells : devoted to molecular & cellular mechanisms Jan 2013 [Refereed]
Asakawa K, Abe G, Kawakami K
Frontiers in neural circuits 7 100 2013 [Refereed]
Fukui H, Shiba D, Asakawa K, Kawakami K, Yokoyama T
FEBS letters 586(16) 2273-2279 Jun 2012 [Refereed]
Pujol-Martí J, Zecca A, Baudoin JP, Faucherre A, Asakawa K, Kawakami K, López-Schier H
The Journal of neuroscience : the official journal of the Society for Neuroscience 32(9) 2976-2987 Feb 2012 [Refereed]
Hirata H, Wen H, Kawakami Y, Naganawa Y, Ogino K, Yamada K, Saint-Amant L, Low SE, Cui WW, Zhou W, Sprague SM, Asakawa K, Muto A, Kawakami K, Kuwada JY
The Journal of biological chemistry 287(2) 1080-1089 Jan 2012 [Refereed]
Asakawa K, Higashijima SI, Kawakami K
Developmental dynamics : an official publication of the American Association of Anatomists 241(2) 327-332 Jan 2012 [Refereed]
Kishimoto N, Alfaro-Cervello C, Shimizu K, Asakawa K, Urasaki A, Nonaka S, Kawakami K, Garcia-Verdugo JM, Sawamoto K
The Journal of comparative neurology 519(17) 3549 Dec 2011 [Refereed]
Asakawa K, Kawakami K
Developmental dynamics : an official publication of the American Association of Anatomists 239(10) 2695-2699 Oct 2010 [Refereed]
Kawakami K, Abe G, Asada T, Asakawa K, Fukuda R, Ito A, Lal P, Mouri N, Muto A, Suster ML, Takakubo H, Urasaki A, Wada H, Yoshida M
BMC developmental biology 10 105 Oct 2010 [Refereed]
Rodríguez-Marí A, Cañestro C, Bremiller RA, Nguyen-Johnson A, Asakawa K, Kawakami K, Postlethwait JH
PLoS genetics 6 e1001034 Jul 2010 [Refereed]
Asakawa K, Kawakami K
Methods (San Diego, Calif.) 49(3) 275-281 Nov 2009 [Refereed]
Koide T, Miyasaka N, Morimoto K, Asakawa K, Urasaki A, Kawakami K, Yoshihara Y
Proceedings of the National Academy of Sciences of the United States of America 106(24) 9884-9889 Jun 2009 [Refereed]
Esaki M, Hoshijima K, Nakamura N, Munakata K, Tanaka M, Ookata K, Asakawa K, Kawakami K, Wang W, Weinberg ES, Hirose S
Developmental biology 329(1) 116-129 May 2009 [Refereed]
Suster ML, Kania A, Liao M, Asakawa K, Charron F, Kawakami K, Drapeau P
Developmental biology 325(2) 422-433 Jan 2009 [Refereed]
Suster ML, Kikuta H, Urasaki A, Asakawa K, Kawakami K
Methods in molecular biology (Clifton, N.J.) 561 41-63 2009 [Refereed]
Urasaki A, Asakawa K, Kawakami K
Proceedings of the National Academy of Sciences of the United States of America 105(50) 19827-19832 Dec 2008 [Refereed]
Asakawa K, Kawakami K
Development, growth & differentiation 50 391-399 Aug 2008 [Refereed]
Nagayoshi S, Hayashi E, Abe G, Osato N, Asakawa K, Urasaki A, Horikawa K, Ikeo K, Takeda H, Kawakami K
Development (Cambridge, England) 135(1) 159-169 Jan 2008 [Refereed]
Asakawa K, Suster ML, Mizusawa K, Nagayoshi S, Kotani T, Urasaki A, Kishimoto Y, Hibi M, Kawakami K
Proceedings of the National Academy of Sciences of the United States of America 105(4) 1255-1260 Jan 2008 [Refereed]
Toya M, Sato M, Haselmann U, Asakawa K, Brunner D, Antony C, Toda T
Nature cell biology 9(6) 646-653 Jun 2007 [Refereed]
Scott EK, Mason L, Arrenberg AB, Ziv L, Gosse NJ, Xiao T, Chi NC, Asakawa K, Kawakami K, Baier H
Nature methods 4(4) 323-326 Apr 2007 [Refereed]
Matsuo Y, Asakawa K, Toda T, Katayama S
Bioscience, biotechnology, and biochemistry 70(8) 1992-1994 Aug 2006 [Refereed]
Asakawa K, Kume K, Kanai M, Goshima T, Miyahara K, Dhut S, Tee WW, Hirata D, Toda T
Molecular biology of the cell 17(3) 1421-1435 Mar 2006 [Refereed]
Cooperation of EB1-Mal3 and the Bub1 spindle checkpoint.
Asakawa K, Toda T
Cell cycle (Georgetown, Tex.) 5 27-30 Jan 2006 [Refereed]
Asakawa K, Toya M, Sato M, Kanai M, Kume K, Goshima T, Garcia MA, Hirata D, Toda T
EMBO reports 6 1194-1200 Dec 2005 [Refereed]
Wang SW, Asakawa K, Win TZ, Toda T, Norbury CJ
Molecular and cellular biology 25(6) 2288-2296 Mar 2005 [Refereed]
A defect of Kap104 alleviates the requirement of mitotic exit network gene functions in Saccharomyces cerevisiae.
Asakawa K, Toh-e A
Genetics 162 1545-1556 Dec 2002 [Refereed]
Yoshida S, Asakawa K, Toh-e A
Current biology : CB 12 944-950 Jun 2002 [Refereed]
A novel functional domain of Cdc15 kinase is required for its interaction with Tem1 GTPase in Saccharomyces cerevisiae
Asakawa K, Yoshida S, Otake F and Toh-e A
Genetics １５７ 1437-1450 2001 [Refereed]
Misc
浦崎 明宏, 浅川 和秀, 川上 浩一
Cell technology. 28(6) 586-591 Jun 2009
Gene trapping
Kazuhide Asakawa
Brenner's Encyclopedia of Genetics, 2nd edn
Conference Activities & Talks
Optogenetic enhancement of TDP-43 intermolecular interaction triggers its cytoplasmic mislocalization and inhibits axon outgrowth of spinal motor neurons
Asakawa Kazuhide
29th International symposium on ALS/MND 7 Dec 2018
Modeling ALS by light illumination
Asakawa Kazuhide
The 41st Annual Meeting of the Molecular Biology Society of Japan 28 Nov 2018
Modeling ALS by light illumination
Asakawa Kazuhide
4th Zebrafish Medaka Drug Discovery Meeting 18 Nov 2018
Optogenetic enhancement of TDP-43 intermolecular interaction triggers its cytoplasmic mislocalization and inhibits axon outgrowth of spinal motor neurons
Asakawa Kazuhide
Neuroscience 2018 3 Nov 2018
Optogenetic enhancement of TDP-43 intermolecular interaction triggers its cytoplasmic mislocalization and inhibits axon outgrowth of spinal motor neurons
Asakawa Kazuhide
5th RNA metabolism in Neurological Disease Conference 1 Nov 2018
Motor neurons become attractable by repulsion
Asakawa Kazuhide
25th Japanese Medaka and Zebrafish Meeting 25 Aug 2018
PI3Kα/mTOR pathway rescues neuronal atrophy induced by aberrant TDP-43 proteostasis in a zebrafish ALS model
Asakawa Kazuhide
The 41st Annual Meeting of the Japan Neuroscience Society 26 Jul 2018
PI3Ka/mTOR pathway rescues TDP-43 toxicity in the spinal motor neuron in zebrafish
Asakawa Kazuhide
8 Dec 2017
An abnormal somatosenseory reflex caused by the loss of VIPL/LMAN2L lectin, a risk factor for mental disorders, in zebrafish [Invited]
asakawa kazuhide
ConBio2017 6 Dec 2017
Activation of PI3K/mTOR pathway alleviates TDP-43-induced axonopathy in the spinal motor neuron in a zebrafish ALS model
asakawa kazuhide
Neuroscience 2017 11 Nov 2017
Research Grants & Projects
THE KATO MEMORIAL TRUST FOR NAMBYO RESEARCH: 第32回研究助成
Project Year: Oct 2018 - Oct 2019 Investigator(s): Asakawa Kazuhide
Nakabayashi Trust For ALS Research: grants-in-aid of The Nakabayashi Trust For ALS Research
Project Year: Sep 2014 - Aug 2016 Investigator(s): Kazuhide Asakawa
筋萎縮性側索硬化症（ALS）に準えた疾患モデルゼブラフィッシュの樹立と解析
Daiichi-Sankyo Foundation of Life Science: 第３０回研究助成
Project Year: Apr 2012 - Mar 2014 Investigator(s): Kazuhide Asakawa
Role of glycoprotein trafficking for the development of locomotion
The Sumitomo Foundation: Grant for Basic Science Research Projects
Project Year: Nov 2012 - May 2014 Investigator(s): Kazuhide Asakawa
Role of the VIPLa-mediated glycoprotein trafficking in locomotion in zebrafish
The NOVARTIS Foundation (Japan) for the Promotion of Science:
Project Year: Apr 2013 - Mar 2014 Investigator(s): Kazuhide Asakawa
Takeda Science Foundation: 2013 年度 医学系研究奨励
Project Year: 2013 Investigator(s): Kazuhide Asakawa
THe Mitsubishi Foundation:
Project Year: Oct 2011 - Sep 2012 Investigator(s): Kazuhide Asakawa
The Center for the Promotion of Integrated Sciences (CPIS) of SOKENDAI:
Project Year: Apr 2011 - Mar 2012 Investigator(s): Kazuhide Asakawa
The Center for the Promotion of Integrated Sciences (CPIS) of SOKENDAI:
Project Year: Apr 2010 - Mar 2011 Investigator(s): Kazuhide Asakawa
The Uehara Memorial Foundation:
Project Year: Apr 2010 - Mar 2011 Investigator(s): Kazuhide Asakawa
The Kao Foundation for Arts and Sciences:
Project Year: Apr 2010 - Mar 2011 Investigator(s): Kazuhide Asakawa
Japan Society for the Promotion of Science: JSPS Research Fellowships for Young Scientists
Project Year: Apr 2006 - Mar 2009 Investigator(s): Kazuhide Asakawa
The Japan Science Society: The Sasakawa Scientific Research Grant
Project Year: Apr 2005 - Mar 2006 Investigator(s): Kazuhide Asakawa
Social Contribution
NIG training course for zebrafish imaging and transgenesis
[Lecturer] 29 Jul 2015 - 8 Aug 2015
17th Japanese Medaka and Zebrafish Meeting
[Editor, Planner, Organizing Member, Others] 8 Sep 2011
