齋藤一樹 (Kazuki Saito) - マイポータル

基本情報

所属: 姫路獨協大学薬学部医療薬学科生物分析化学研究室教授

学位: 理学博士(東京大学)

研究者番号: 10192585
J-GLOBAL ID: 201801019283510787
researchmap会員ID: B000311721

外部リンク: http://www.himeji-du.ac.jp/faculty/dp_pharm/pharm/bioanalysis/laboratory/members_saito.html

論文

Ligand-dependent responses of the silkworm prothoracicotropic hormone receptor, Torso, are maintained by unusual intermolecular disulfide bridges in the transmembrane region

Tadafumi Konogami, Yiwen Yang, Mari H. Ogihara, Juri Hikiba, Hiroshi Kataoka, Kazuki Saito

SCIENTIFIC REPORTS 6 2016年3月査読有り
Application of plug-plug technique to ACE experiments for discovery of peptides binding to a larger target protein: A model study of calmodulin- binding fragments selected from a digested mixture of reduced BSA

Kazuki Saito, Mamiko Nakato, Takaaki Mizuguchi, Shinji Wada, Hiromasa Uchimura, Hiroshi Kataoka, Shigeyuki Yokoyama, Hiroshi Hirota, Yoshiaki Kiso

ELECTROPHORESIS 35(6) 846-854 2014年3月査読有り
Simultaneous quantification of individual intermediate steroids in silkworm ecdysone biosynthesis by liquid chromatography-tandem mass spectrometry with multiple reaction monitoring.

Juri Hikiba, Mari H Ogihara, Masatoshi Iga, Kazuki Saito, Yoshinori Fujimoto, Minoru Suzuki, Hiroshi Kataoka

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 915-916 52-6 2013年2月1日査読有り
Molecular basis of wing coloration in a batesian mimic butterfly, papilio polytes

Hideki Nishikawa, Masatoshi Iga, Junichi Yamaguchi, Kazuki Saito, Hiroshi Kataoka, Yutaka Suzuki, Sumio Sugano, Haruhiko Fujiwara

Scientific Reports 3 2013年査読有り
Evaluation of dimerization-inhibitory activities of cyclic peptides containing a beta-hairpin loop sequence of the EGF receptor

Takaaki Mizuguchi, Naho Ohara, Mika Iida, Ryunosuke Ninomiya, Shinji Wada, Yoshiaki Kiso, Kazuki Saito, Kenichi Akaji

BIOORGANIC & MEDICINAL CHEMISTRY 20(19) 5730-5737 2012年10月査読有り
Intact-cell-based surface plasmon resonance measurements for ligand affinity evaluation of a membrane receptor

Takaaki Mizuguchi, Hiromasa Uchimura, Hiroshi Kataoka, Kenichi Akaji, Yoshiaki Kiso, Kazuki Saito

ANALYTICAL BIOCHEMISTRY 420(2) 185-187 2012年1月査読有り
Quantitative evaluation of refolding conditions for a disulfide-bond-containing protein using a concise O-18-labeling technique

Hiromasa Uchimura, Yusam Kim, Takaaki Mizuguchi, Yoshiaki Kiso, Kazuki Saito

PROTEIN SCIENCE 20(6) 1090-1096 2011年6月査読有り
Verification of protein disulfide bond arrangement by in-gel tryptic digestion under entirely neutral pH conditions

Kazuki Saito, Itsuki Yasuo, Hiromasa Uchimura, Shizuyo Koide-Yoshida, Takaaki Mizuguchi, Yoshiaki Kiso

PROTEOMICS 10(7) 1505-1509 2010年4月査読有り
Inhibitory effect of a dimerization-arm-mimetic peptide on EGF receptor activation

Takaaki Mizuguchi, Hiromasa Uchimura, Taeko Kakizawa, Tooru Kimura, Shigeyuki Yokoyama, Yoshiaki Kiso, Kazuki Saito

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 19(12) 3279-3282 2009年6月査読有り
BACE1 inhibitors: Optimization by replacing the P-1 ' residue with non-acidic moiety

Yoshio Hamada, Hamdy Abdel-Rahman, Abdellah Yamani, Jeffrey-Tri Nguyen, Monika Stochaj, Koushi Hidaka, Tooru Kimura, Yoshio Hayashi, Kazuki Saito, Shoichi Ishiura …

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 18(5) 1649-1653 2008年3月査読有り
Novel non-peptidic and small-sized BACE1 inhibitors

Yoshio Hamada, Hiroko Ohta, Naoko Miyamoto, Ryoji Yamaguchi, Abdellah Yamani, Koushi Hidaka, Tooru Kimura, Kazuki Saito, Yoshio Hayashi, Shoichi Ishiura …

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 18(5) 1654-1658 2008年3月査読有り
Fmoc-based solid phase chemical synthesis of 71-meric neuregulin 1-beta 1, an epidermal growth factor-like domain

Taeko Kakizawa, Shizuyo Koide-Yoshida, Tooru Kimura, Hiromasa Uchimura, Yoshio Hayashi, Kazuki Saito, Yoshiaki Kiso

JOURNAL OF PEPTIDE SCIENCE 14(3) 261-266 2008年3月査読有り
NTA-mediated protein capturing strategy in screening experiments for small organic molecules by surface plasmon resonance

Naoei Yoshitani, Kazuki Saito, Wakana Saikawa, Miwako Asanuma, Shigeyuki Yokoyama, Hiroshi Hirota

PROTEOMICS 7(4) 494-499 2007年2月査読有り
Non-peptidic small-sized BACE1 inhibitors: Optimization based on the docked inhibitor's conformer in BACE1

Y. Hamada, N. Miyamoto, R. Yamaguchi, A. Yamani, K. Hidaka, H-O. Kumada, T. Kimura, K. Saito, Y. Hayashi, S. Ishiura …

BIOPOLYMERS 88(4) 567-567 2007年査読有り
beta-Secretase inhibitors: Modification at the P-4 position and improvement of inhibitory activity in cultured cells

Yoshio Hamada, Naoto Igawa, Hayato Ikari, Zyta Ziora, Jeffrey-Tri Nguyen, Abdellah Yamani, Koushi Hidaka, Tooru Kimura, Kazuki Saito, Yoshio Hayashi …

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 16(16) 4354-4359 2006年8月査読有り
Design and synthesis of potent beta-secretase (BACE1) inhibitors with P-1 ' carboxylic acid bioisosteres

T Kimura, Y Hamada, M Stochaj, H Ikari, A Nagamine, H Abdel-Rahman, N Igawa, K Hidaka, JT Nguyen, K Saito …

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 16(9) 2380-2386 2006年5月査読有り
A structure-based strategy for discovery of small ligands binding to functionally unknown proteins: Combination of in silico screening and surface plasmon resonance measurements

N Yoshitani, K Satou, K Saito, S Suzuki, H Hatanaka, M Seki, K Shinozaki, H Hirota, S Yokoyama

PROTEOMICS 5(6) 1472-1480 2005年4月査読有り
A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling

M Hatakeyama, S Kimura, T Naka, T Kawasaki, N Yumoto, M Ichikawa, JH Kim, K Saito, M Saeki, M Shirouzu …

BIOCHEMICAL JOURNAL 373 451-463 2003年7月査読有り
Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells

K Sakamoto, A Hayashi, A Sakamoto, D Kiga, H Nakayama, A Soma, T Kobayashi, M Kitabatake, K Takio, K Saito …

NUCLEIC ACIDS RESEARCH 30(21) 4692-4699 2002年11月査読有り
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

H Ogiso, R Ishitani, O Nureki, S Fukai, M Yamanaka, JH Kim, K Saito, A Sakamoto, M Inoue, M Shirouzu …

CELL 110(6) 775-787 2002年9月査読有り

もっとみる