2022年7月18日
Palladium-catalyzed solid-state borylation of aryl halides using mechanochemistry
Beilstein Journal of Organic Chemistry
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- 巻
- 18
- 号
- 開始ページ
- 855
- 終了ページ
- 862
- 記述言語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.3762/bjoc.18.86
- 出版者・発行元
- Beilstein Institut
This study describes the solid-state palladium-catalyzed cross-coupling between aryl halides and bis(pinacolato)diboron using ball milling. The reactions were completed within 10 min for most aryl halides to afford a variety of synthetically useful arylboronates in high yields. Notably, all experimental operations could be performed in air, and did not require the use of large amounts of dry and degassed organic solvents. The utility of this method was further demonstrated by gram-scale synthesis under solvent-free, mechanochemical conditions.
- リンク情報
- ID情報
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- DOI : 10.3762/bjoc.18.86
- eISSN : 1860-5397