Binary Ti-Fe alloys with 5-25 mass% Fe were prepared, and subjected to reciprocating wear test. The aim of this study was to investigate the relationship between mechanical properties and the wear resistance of titanium and Ti-Fe alloys. The dimensions (length, width and depth) of wear marks on Ti-Fe alloys were less than those observed on pure Ti specimen. Wear resistance of Ti-Fe alloys was better than that of pure titanium. It was established that hardness was the main factor that influenced wear resistance of Ti-Fe alloys. Single β Ti-Fe alloys showed better wear resistance than α+β Ti-Fe alloys. Increase in concentration of Fe in the β phase of Ti-Fe alloys leads to improved wear resistance of the alloy. Ti-Fe alloys with 11-15 mass% Fe form ideal candidates for fabrication of dental titanium alloys with excellent wear resistance.