脇坂啓子 (keiko wakisaka tsuji) - マイポータル

基本情報

所属: 順天堂大学神経学講座研究員

研究者番号: 70432309
J-GLOBAL ID: 202001014754810863
researchmap会員ID: R000009838

論文

Drosophila Alpha-ketoglutarate-dependent dioxygenase AlkB is involved in repair from neuronal disorders induced by ultraviolet damage.

Keiko Tsuji Wakisaka, Yuuka Muraoka, Jo Shimizu, Mizuki Yamaguchi, Ibuki Ueoka, Ikuko Mizuta, Hideki Yoshida, Masamitsu Yamaguchi

Neuroreport 30(15) 1039-1047 2019年9月9日査読有り
The dawn of pirna research in various neuronal disorders.

Keiko Tsuji Wakisaka, Yuzuru Imai

Frontiers in bioscience (Landmark edition) 24 1440-1451 2019年6月1日査読有り
A trafficking-deficient KCNQ1 mutation, T587M, causes a severe phenotype of long QT syndrome by interfering with intracellular hERG transport.

Jie Wu, Tomoko Sakaguchi, Kotoe Takenaka, Futoshi Toyoda, Keiko Tsuji, Hiroshi Matsuura, Minoru Horie

Journal of cardiology 73(5) 343-350 2019年5月査読有り
Novel roles of Drosophila FUS and Aub responsible for piRNA biogenesis in neuronal disorders.

Keiko Tsuji Wakisaka, Ryo Tanaka, Tomoki Hirashima, Yuuka Muraoka, Yumiko Azuma, Hideki Yoshida, Takahiko Tokuda, Satoshi Asada, Kojiro Suda, Kenji Ichiyanagi …

Brain research 1708 207-219 2019年4月1日査読有り
Association of zygotic piRNAs derived from paternal P elements with hybrid dysgenesis in Drosophila melanogaster.

Keiko Tsuji Wakisaka, Kenji Ichiyanagi, Seiko Ohno, Masanobu Itoh

Mobile DNA 9 7-7 2018年査読有り
Diversity of P-element piRNA production among M' and Q strains and its association with P-M hybrid dysgenesis in Drosophila melanogaster.

Keiko Tsuji Wakisaka, Kenji Ichiyanagi, Seiko Ohno, Masanobu Itoh

Mobile DNA 8 13-13 2017年査読有り
Identification and functional characterization of KCNQ1 mutations around the exon 7-intron 7 junction affecting the splicing process.

Keiko Tsuji-Wakisaka, Masaharu Akao, Takahiro M Ishii, Takashi Ashihara, Takeru Makiyama, Seiko Ohno, Futoshi Toyoda, Kenichi Dochi, Hiroshi Matsuura, Minoru Horie

Biochimica et biophysica acta 1812(11) 1452-9 2011年11月査読有り
A novel KCNJ2 nonsense mutation, S369X, impedes trafficking and causes a limited form of Andersen-Tawil syndrome.

Takahiro Doi, Takeru Makiyama, Takeshi Morimoto, Yoshisumi Haruna, Keiko Tsuji, Seiko Ohno, Masaharu Akao, Yoshiaki Takahashi, Takeshi Kimura, Minoru Horie

Circulation. Cardiovascular genetics 4(3) 253-60 2011年6月査読有り
A family of hereditary long QT syndrome caused by Q738X HERG mutation.

Shioto Yasuda, Shin-Ichi Hiramatsu, Keita Odashiro, Toru Maruyama, Keiko Tsuji, Minoru Horie

International journal of cardiology 144(1) 69-72 2010年9月24日査読有り
Adrenergic regulation of the rapid component of delayed rectifier K+ current: implications for arrhythmogenesis in LQT2 patients.

Dimitar P Zankov, Hidetada Yoshida, Keiko Tsuji, Futoshi Toyoda, Wei-Guang Ding, Hiroshi Matsuura, Minoru Horie

Heart rhythm 6(7) 1038-46 2009年7月査読有り
Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome.

Seiko Ohno, Futoshi Toyoda, Dimitar P Zankov, Hidetada Yoshida, Takeru Makiyama, Keiko Tsuji, Toshihiro Honda, Kazuhiko Obayashi, Hisao Ueyama, Wataru Shimizu …

Human mutation 30(4) 557-63 2009年4月査読有り
Cinnamyl-3,4-dihydroxy-alpha-cyanocinnamate and nordihydroguaiaretic acid inhibit human Kv1.5 currents independently of lipoxygenase.

Ying-Zi Gong, Wei-Guang Ding, Jie Wu, Keiko Tsuji, Minoru Horie, Hiroshi Matsuura

European journal of pharmacology 600(1-3) 18-25 2008年12月14日査読有り
Hydroxyzine, a first generation H(1)-receptor antagonist, inhibits human ether-a-go-go-related gene (HERG) current and causes syncope in a patient with the HERG mutation.

Tomoko Sakaguchi, Hideki Itoh, Wei-Guang Ding, Keiko Tsuji, Iori Nagaoka, Yuko Oka, Takashi Ashihara, Makoto Ito, Yoshihiro Yumoto, Naoko Zenda …

Journal of pharmacological sciences 108(4) 462-71 2008年12月査読有り
A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation.

Takeru Makiyama, Masaharu Akao, Satoshi Shizuta, Takahiro Doi, Kei Nishiyama, Yuko Oka, Seiko Ohno, Yukiko Nishio, Keiko Tsuji, Hideki Itoh …

Journal of the American College of Cardiology 52(16) 1326-34 2008年10月14日査読有り
A Novel SCN5A Gain-of-Function Mutation M1875T Associated with Familial Atrial Fibrillation

Takeru Makiyama, Masaharu Akao, Satoshi Shizuta, Takahiro Doi, Kel Nishiyama, Oka Yuko, Yukiko Nishio, Keiko Tsuji, Hideki Itoh, Takeshi Kimura …

CIRCULATION 118(18) S343-S343 2008年10月査読有り
Identification and Functional Characterization of a Novel Intronic Splicing Mutation in KCNQ1 Associated with Long QT Syndrome

Keiko Tsuji, Masaharu Akao, Takahiro Ishii, Takashi Ashihara, Takeru Makiyama, Seiko Ohno, Futoshi Toyoda, Yukiko Nishio, Tomoko Sakaguchi, Hiroshi Matsuura …

CIRCULATION 118(18) S988-S988 2008年10月査読有り
Mutation analysis of the glycerol-3 phosphate dehydrogenase-1 like (GPD1L) gene in Japanese patients with Brugada syndrome.

Takeru Makiyama, Masaharu Akao, Yoshisumi Haruna, Keiko Tsuji, Takahiro Doi, Seiko Ohno, Yukiko Nishio, Toru Kita, Minoru Horie

Circulation journal : official journal of the Japanese Circulation Society 72(10) 1705-6 2008年10月査読有り
Age- and genotype-specific triggers for life-threatening arrhythmia in the genotyped long QT syndrome.

Tomoko Sakaguchi, Wataru Shimizu, Hideki Itoh, Takashi Noda, Yoshihiro Miyamoto, Iori Nagaoka, Yuko Oka, Takashi Ashihara, Makoto Ito, Keiko Tsuji …

Journal of cardiovascular electrophysiology 19(8) 794-9 2008年8月査読有り
A novel mutation associated with Jervell and Lange-Nielsen syndrome in a Japanese family.

Seiko Ohno, Tomoyuki Kubota, Hidetada Yoshida, Keiko Tsuji, Takeru Makiyama, Satsuki Yamada, Keisuke Kuga, Iwao Yamaguchi, Toru Kita, Minoru Horie

Circulation journal : official journal of the Japanese Circulation Society 72(5) 687-93 2008年5月査読有り
Mutation site dependent variability of cardiac events in Japanese LQT2 form of congenital long-QT syndrome.

Iori Nagaoka, Wataru Shimizu, Hideki Itoh, Satoshi Yamamoto, Tomoko Sakaguchi, Yuko Oka, Keiko Tsuji, Takashi Ashihara, Makoto Ito, Hidetada Yoshida …

Circulation journal : official journal of the Japanese Circulation Society 72(5) 694-9 2008年5月査読有り

もっとみる

MISC

スプライシング異常と循環器疾患

脇坂啓子, 堀江稔

循環器内科 70(5) 523-529 2011年11月
3CN5A and Lamin A/C Gone Mutations are Highly Prevalent In Patients with Familial Bradyarrhythmic Disorders

Takeru Maklyama, Masaharu Akao, Satoshi Shizuta, Takahiro Doi, Seiko Ohno, Yukko Nishio, Keiko Tsuji, Hideki Itoh, Toru Kita, Minoru Horie

CIRCULATION 118(18) S873-S873 2008年10月
Age-related triggers for life-threatning arrhythmia in the genotyped long QT syndrome

Tomoko Sakaguchi, Wataru Shimizu, Hideki Ito, Takashi Noda, Yoshihiro Miyamoto, Iori Nagaoka, Takashi Ashihara, Makoto Ito, Keiko Tsuji, Seiko Ohno …

CIRCULATION 116(16) 584-584 2007年10月
A novel KCNH2 mutation associated with the short QT interval of Brugada syndrome: Impaired deactivation for the I-Kr channel

Hideki Itoh, Tomoko Sakaguchi, Wei-Guang Ding, Keiko Tsuji, Takashi Ashihara, Yuko Nakazawa, Hikari Jo, Takenori Yao, Makoto Ito, Hiroshi Matsuura …

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 49(9) 30A-30A 2007年3月
Characterization of a novel missense mutation in the pore of HERG in a patient with long QT syndrome

Hidetada Yoshida, Minoru Horie, Hideo Otani, Makoto Takano, Keiko Tsuji, Tomoyuki Kubota, Masatake Fukunami, Shigetake Sasayama

Journal of Cardiovascular Electrophysiology 10(9) 1262-1270 1999年

共同研究・競争的資金等の研究課題

胎生期のアストロサイト発生におけるPINK1, Parkinの新たな役割

日本学術振興会科学研究費助成事業若手研究 2021年4月 - 2023年3月

脇坂啓子