Keiko YASUDA

Profile Information

Affiliation: 特定助教, 医学専攻分子生体統御学講座医化学, 京都大学大学院医学研究科

Degree: Ph.D. (Medicine)(Mar, 2019, Osaka University)

J-GLOBAL ID: 201901007589445554
researchmap Member ID: B000372837

Research Areas

Life sciences / Immunology /

Awards

Dec, 2021

若手女性研究者研究支援事業, 自己免疫疾患発症に寄与するT細胞のリンパ組織内局在に着目した特性の解明, 日本免疫学会

安田圭子
Jan, 2019

The 8th NIF(Network of Immunology Frontier) Winter School of advanced immunology travel award
Oct, 2018

6th Annual Meeting-International Cytokine & Interferon Society Milstein Travel Award
2018

Tadamitsu Kishimoto International Travel Award, Satb1-Mediated Regulation of GM-CSF And PD-1 in Pathogenic Th17 Cells
Oct, 2011

第22回日本急性血液浄化学会学術集会Best Presentation Award, MCP遺伝子異常を認めた再発性atypical HUSの一例

〇安田圭子、佐々木公一、林晃正、倭正也
2011

腎臓内科学研究奨励賞, 大阪腎疾患研究会

安田圭子
May, 2008

第183回近畿外科学会優秀演題, ポリープ合併S状結腸巨大憩室の1例

〇安田圭子、藤井眞、岩瀬和裕、他8名

Papers

Abnormal glomerular basement membrane maturation impairs mesangial cell differentiation during murine postnatal nephrogenesis

Kozue Uchio-Yamada, Keiko Yasuda, Kentaro Oh-hashi, Noboru Manabe

American Journal of Physiology-Renal Physiology, 324(1) F124-F134, Nov 23, 2022
Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells.

Ryoji Kawakami, Yohko Kitagawa, Kelvin Y Chen, Masaya Arai, Daiya Ohara, Yamami Nakamura, Keiko Yasuda, Motonao Osaki, Norihisa Mikami, Caleb A Lareau …

Immunity, 54(5) 947-961, May 11, 2021
Tensin2 is important for podocyte-glomerular basement membrane interaction and integrity of glomerular filtration barrier.

Kozue Uchio-Yamada, Keiko Yasuda, Yoko Monobe, Ken-Ichi Akagi, Osamu Suzuki, Noboru Manabe

American journal of physiology. Renal physiology, 318(6) F1520-F1530, May 11, 2020 Peer-reviewed
Dynamics of D-serine reflected the recovery course of a patient with rapidly progressive glomerulonephritis.

Atsushi Hesaka, Keiko Yasuda, Shinsuke Sakai, Hiroaki Yonishi, Tomoko Namba-Hamano, Atsushi Takahashi, Masayuki Mizui, Kenji Hamase, Rakan Matsui, Masashi Mita …

CEN case reports, 8(4) 297-300, Nov, 2019 Peer-reviewed
Identification of a genomic enhancer that enforces proper apoptosis induction in thymic negative selection.

Miki Arai Hojo, Kyoko Masuda, Hiroaki Hojo, Yosuke Nagahata, Keiko Yasuda, Daiya Ohara, Yusuke Takeuchi, Keiji Hirota, Yutaka Suzuki, Hiroshi Kawamoto …

Nature communications, 10(1) 2603-2603, Jun 13, 2019 Peer-reviewed
The pathogenicity of Th17 cells in autoimmune diseases.

Yasuda K, Takeuchi Y, Hirota K

Seminars in immunopathology, 41(3) 283-297, May, 2019 Peer-reviewed
Correction to: The pathogenicity of Th17 cells in autoimmune diseases.

Yasuda K, Takeuchi Y, Hirota K

Seminars in immunopathology, 41(3) 299, May, 2019 Peer-reviewed
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation.

Yasuda K, Kitagawa Y, Kawakami R, Isaka Y, Watanabe H, Kondoh G, Kohwi-Shigematsu T, Sakaguchi S, Hirota K

Nature communications, 10(1) 549, Feb, 2019 Peer-reviewed
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.

Keiji Hirota, Motomu Hashimoto, Yoshinaga Ito, Mayumi Matsuura, Hiromu Ito, Masao Tanaka, Hitomi Watanabe, Gen Kondoh, Atsushi Tanaka, Keiko Yasuda …

Immunity, 48(6) 1220-1232, Jun 19, 2018 Peer-reviewed
An inflammatory cellular cascade of autoimmune Th17 cells, GM-CSF-producing ILC2 and synoviocytes in the development of autoimmune arthritis

Hirota, K, Ito, Y, Hashimoto, M, Watanabe, H, Kondoh, G, Tanaka, A, Yasuda, K, Kopf, M, Potocnik, AJ, Stockinger, B …

Immunity, 48(6) 1220-1232, Jun, 2018 Peer-reviewed
Prognostic Significance of Asymptomatic Brain Natriuretic Peptide Elevation at Nephrology Referral in Patients with Chronic Kidney Disease.

Terumasa Hayashi, Keiko Yasuda, Tomonori Kimura, Koichi Sasaki, Karin Shimada, Nobuhiro Hashimoto, Yoshitaka Isaka

American journal of nephrology, 48(3) 205-213, 2018 Peer-reviewed
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment (vol 18, pg 173, 2017)

Yohko Kitagawa, Naganari Ohkura, Yujiro Kidani, Alexis Vandenbon, Keiji Hirota, Ryoji Kawakami, Keiko Yasuda, Daisuke Motooka, Shota Nakamura, Motonari Kondo …

NATURE IMMUNOLOGY, 18(11) 1270-1270, Nov, 2017 Peer-reviewed
Cardiac troponin T elevation at dialysis initiation is associated with all-cause and cardiovascular mortality on dialysis in patients without diabetic nephropathy

Terumasa Hayashi, Tomonori Kimura, Keiko Yasuda, Koichi Sasaki, Yoshitsugu Obi, Hiromi Rakugi, Yoshitaka Isaka

CLINICAL AND EXPERIMENTAL NEPHROLOGY, 21(2) 333-341, Apr, 2017 Peer-reviewed
Erratum: Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment.

Kitagawa Y, Ohkura N, Kidani Y, Vandenbon A, Hirota K, Kawakami R, Yasuda K, Motooka D, Nakamura S, Kondo M …

Nature immunology, 18(4) 474, Mar, 2017 Peer-reviewed
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment

Yohko Kitagawa, Naganari Ohkura, Yujiro Kidani, Alexis Vandenbon, Keiji Hirota, Ryoji Kawakami, Keiko Yasuda, Daisuke Motooka, Shota Nakamura, Motonari Kondo …

NATURE IMMUNOLOGY, 18(2) 173-183, Feb, 2017 Peer-reviewed
Chiral amino acid metabolomics for novel biomarker screening in the prognosis of chronic kidney disease

Tomonori Kimura, Kenji Hamase, Yurika Miyoshi, Ryohei Yamamoto, Keiko Yasuda, Masashi Mita, Hiromi Rakugi, Terumasa Hayashi, Yoshitaka Isaka

SCIENTIFIC REPORTS, 6 26137, May, 2016 Peer-reviewed
Identification of biomarkers for development of end-stage kidney disease in chronic kidney disease by metabolomic profiling

Tomonori Kimura, Keiko Yasuda, Ryohei Yamamoto, Tomoyoshi Soga, Hiromi Rakugi, Terumasa Hayashi, Yoshitaka Isaka

SCIENTIFIC REPORTS, 6 26138, May, 2016 Peer-reviewed
Early Nephrology Referral 6 Months Before Dialysis Initiation Can Reduce Early Death But Does Not Improve Long-Term Cardiovascular Outcome on Dialysis

Terumasa Hayashi, Tomonori Kimura, Keiko Yasuda, Koichi Sasaki, Yoshitsugu Obi, Harumi Nagayama, Motoki Ohno, Kazusei Uematsu, Takehiro Tamai, Takahiro Nishide …

CIRCULATION JOURNAL, 80(4) 1008-+, Apr, 2016 Peer-reviewed
Laparoscopy Reveals a Diversity of Peritoneal Change in Patients with Long-Term Vintage of Peritoneal Dialysis

Koichi Sasaki, Hitoshi Mizuno, Noriyuki Iwamoto, Masami Imakita, Keiko Yasuda, Tomonori Kimura, Hiromi Rakugi, Yoshitaka Isaka, Terumasa Hayashi

BLOOD PURIFICATION, 41(1-3) 48-54, 2016 Peer-reviewed
Membranous nephropathy secondary to Graves' disease with deposits of thyroid peroxidase in an adult.

Koichi Sasaki, Keiko Yasuda, Koichi Nakanishi, Hiromi Rakugi, Yoshitaka Isaka, Masaya Yamato

CEN case reports, 3(1) 90-93, May, 2014 Peer-reviewed

Misc.

外来RNAの分解とその制御機構

安田圭子, 竹内理

実験医学, 40(4) 521-526, Mar, 2022 Lead author
Inflammatory circuit of Th17 cells, fibroblast-like synoviocytes, and ILCs in the development of autoimmune arthritis

K. Hirota, Y. Ito, M. Hashimoto, H. Watanabe, G. Kondoh, A. Tanaka, K. Yasuda, M. Kopf, A. J. Potocnik, B. Stockinger …

EUROPEAN JOURNAL OF IMMUNOLOGY, 46 29-29, Aug, 2016
ゲノムオーガナイザーSatb1は制御性T細胞特異的なsuper-enhancerを構築し分化を成立させる

北川瑶子, 大倉永也, 廣田圭司, 安田圭子, 近藤元就, 谷内一郎, Kohwi-Shigematsu Terumi, 坂口志文

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回 [2T25p-03(2P0653)], Dec, 2015
Anti-1-Adrenergic Receptor Autoantibody is an Independent Predictor of All Cause Mortality in Dialysis Patients

Masaya Yamato, Keiko Yasuda, Koichi Sasaki, Terumasa Hayashi, Hiromi Rakugi, Yoshitaka Isaka

CIRCULATION, 126(21), Nov, 2012
INFLUENCE OF INTRADIALYSIS HEART RATE AT INITIATION OF HAEMODIALYSIS ON LONG-TERM OUTCOME

Koichi Sasaki, Keiko Yasuda, Masaya Yamato

NEPHROLOGY DIALYSIS TRANSPLANTATION, 27 200-200, May, 2012
A PILOT STUDY OF ANTI-BETA1-ADRENERGIC RECEPTOR ANTIBODIES IN CKD PATIENTS

Masaya Yamato, Keiko Yasuda, Koichi Sasaki

NEPHROLOGY DIALYSIS TRANSPLANTATION, 27 399-399, May, 2012

Research Projects

新規ヒト膜性腎症モデルの確立と病態機序解明-治療法開発をめざして-

Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2023
新規治療法開発をめざした膜性腎症マウスモデルの確立

日本腎臓病協会・大塚製薬共同事業「共同研究」, Oct, 2020 - Sep, 2022
病態解明をめざした新規膜性腎症マウスモデルの確立-病理組織学的変化に着目して-

2020年度(第49回)かなえ医薬振興財団研究助成金, Apr, 2021 - Mar, 2022
新規ヒト膜性腎症モデルの確立と病態機序解明-治療法開発にむけて‐

第31回(2020年度)加藤記念研究助成, Apr, 2020 - Mar, 2022
膜性腎症モデルマウスの確立-難治性ネフローゼ症候群の機序解明へ-

大阪難病研究財団令和2年度医学研究助成, Sep, 2020 - Mar, 2021
RNA結合蛋白に着目したHIV感染制御機構の解明

令和2年度一般財団法人藤原記念財団奨励金, Jul, 2020 - Mar, 2021

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