Kei Saito

Profile Information

Affiliation: National Institute of Genetics

Degree: 博士（学術）(Mar, 2021, 東京大学)

Researcher number: 10908007
J-GLOBAL ID: 202101008019401469
researchmap Member ID: R000020756

Research Interests

Research Areas

Life sciences / Biophysics /

Research History

Mar, 2021 - Present

National Institute of Genetics

Education

Apr, 2018 - Mar, 2021

Graduate School of Arts and Sciences, The University of Tokyo
Apr, 2011 - Mar, 2013

Graduate School of Arts and Sciences, The University of Tokyo
Apr, 2006 - Mar, 2011

College of Arts and Sciences, The University of Tokyo

Papers

Confined-microtubule assembly shapes three-dimensional cell wall structures in xylem vessels

Takema Sasaki, Kei Saito, Daisuke Inoue, Henrik Serk, Yuki Sugiyama, Edouard Pesquet, Yuta Shimamoto, Yoshihisa Oda

Nature Communications, 14(1), Nov 13, 2023
Morphological growth dynamics, mechanical stability, and active microtubule mechanics underlying spindle self-organization

Tatsuya Fukuyama, Lucan Yan, Masahito Tanaka, Megumi Yamaoka, Kei Saito, Shih-Chieh Ti, Chung-Chi Liao, Kuo-Chiang Hsia, Yusuke T. Maeda, Yuta Shimamoto

Proceedings of the National Academy of Sciences, 119(44), Nov, 2022
Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.

Takuya Kobayashi, Akihisa Tsutsumi, Nagomi Kurebayashi, Kei Saito, Masami Kodama, Takashi Sakurai, Masahide Kikkawa, Takashi Murayama, Haruo Ogawa

Nature communications, 13(1) 2821-2821, May 20, 2022
Conformational diversity of dynactin sidearm and domain organization of its subunit p150.

Kei Saito, Takashi Murayama, Tomone Hata, Takuya Kobayashi, Keitaro Shibata, Saiko Kazuno, Tsutomu Fujimura, Takashi Sakurai, Yoko Y Toyoshima

Molecular biology of the cell, 31(12) 1218-1231, Jun 1, 2020
Circular orientation fluorescence emitter imaging (COFEI) of rotational motion of motor proteins.

Mitsuhiro Sugawa, Tomoko Masaike, Nagisa Mikami, Shin Yamaguchi, Keitaro Shibata, Kei Saito, Fumihiko Fujii, Yoko Y Toyoshima, Takayuki Nishizaka, Junichiro Yajima

Biochemical and biophysical research communications, 504(4) 709-714, Oct 12, 2018
Axonemal dynein light chain-1 locates at the microtubule-binding domain of the γ heavy chain.

Muneyoshi Ichikawa, Kei Saito, Haru-Aki Yanagisawa, Toshiki Yagi, Ritsu Kamiya, Shin Yamaguchi, Junichiro Yajima, Yasuharu Kushida, Kentaro Nakano, Osamu Numata …

Molecular biology of the cell, 26(23) 4236-47, Nov 15, 2015
Torque generation by axonemal outer-arm dynein.

Shin Yamaguchi, Kei Saito, Miki Sutoh, Takayuki Nishizaka, Yoko Y Toyoshima, Junichiro Yajima

Biophysical journal, 108(4) 872-879, Feb 17, 2015
Autoinhibition and cooperative activation mechanisms of cytoplasmic dynein.

Takayuki Torisawa, Muneyoshi Ichikawa, Akane Furuta, Kei Saito, Kazuhiro Oiwa, Hiroaki Kojima, Yoko Y Toyoshima, Ken'ya Furuta

Nature cell biology, 16(11) 1118-24, Nov, 2014
A single protofilament is sufficient to support unidirectional walking of dynein and kinesin.

Keitaro Shibata, Michi Miura, Yuta Watanabe, Kei Saito, Atsuko Nishimura, Ken'ya Furuta, Yoko Y Toyoshima

PloS one, 7(8) e42990, 2012

Misc.

New Folding Pattern of P150 and "Anntena'' for Dynein Binding

Kei Saito, Takashi Murayama, Tomonori Hata, Takuya Kobayashi, Yoko Y. Toyoshima

BIOPHYSICAL JOURNAL, 106(2) 353A-354A, Jan, 2014
Self-Regulation of Cytoplasmic Dynein through its Unconventional Force Response

Takayuki Torisawa, Ken'ya Furuta, Akane Furuta, Muneyoshi Ichikawa, Kei Saito, Kazuhiro Oiwa, Hiroaki Kojima, Yoko Yano Toyoshima

BIOPHYSICAL JOURNAL, 106(2) 443A-443A, Jan, 2014
1P164 Torque generation by axonemal outer-arm dynein(11. Molecular motor,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

Yamaguchi Shin, Saito Kei, Sutoh Miki, Nishizaka Takayuki, Toyoshima Yoko Y, Yajima Junichiro

Seibutsu Butsuri, 54(1) S168, 2014
3P164 Autoinhibition and cooperative activation mechanisms of cytoplasmic dynein(Molecular motor,Poster,The 52th Annual Meeting of the Biophysical Society of Japan(BSJ2014))

Takayuki Torisawa, Ken'ya Furuta, Muneyoshi Ichikawa, Akane Furuta, Kei Saito, Kazuhiro Oiwa, Hiroaki Kojima, Yoko Toyoshima

Seibutsu Butsuri, 54(1) S276, 2014
Self-regulation of cytoplasmic dynein

K. Furuta, T. Torisawa, A. Furuta, M. Ichikawa, K. Saito, K. Oiwa, H. Kojima, Y. Y. Toyoshima

MOLECULAR BIOLOGY OF THE CELL, 24, 2013
2A1448 Nucleotide-dependent morphological change of cytoplasmic dynein(Molecular Motors II:Dynein,Oral Presentation,The 50th Annual Meeting of the Biophysical Society of Japan)

Ichikawa Muneyoshi, Saito Kei, Torisawa Takayuki, Shibata Keitaro, Watanabe Yuta, Hata Tomonori, Toyoshima Yoko

Seibutsu Butsuri, 52 S38-S39, 2012

Professional Memberships

日本生物物理学会

Research Projects

4量体キネシンとTPX2の一分子構造機能解析による紡錘体超構造の形成機構の解明

科学研究費助成事業, 若手研究, 日本学術振興会, Apr, 2022 - Mar, 2025

斎藤慧
４量体キネシンの制御による微小管高次ネットワークの形成メカニズム

科学研究費助成事業, 研究活動スタート支援, 日本学術振興会, Aug, 2021 - Mar, 2023

斎藤慧

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