2022年6月14日
Osmotic second virial coefficients for hydrophobic interactions as a function of solute size
The Journal of Chemical Physics
- ,
- ,
- ,
- 巻
- 156
- 号
- 22
- 開始ページ
- 221104
- 終了ページ
- 221104
- 記述言語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1063/5.0097547
- 出版者・発行元
- AIP Publishing
To gain quantitative insight into how the overall strength of the hydrophobic interaction varies with the molecular size, we calculate osmotic second virial coefficients B for hydrophobic spherical molecules of different diameters σ in water based on molecular simulation with corrections to the finite-size and finite-concentration effects. It is shown that B (<0) changes by two orders of magnitude greater as σ increases twofold and its solute-size dependence is best fit by a power law B ∝ σ α with the exponent α ≃ 6, which contrasts with the cubic power law that the second virial coefficients of gases obey. It is also found that values of B for the solutes in a nonpolar solvent are positive but they obey the same power law as in water. A thermodynamic identity for B derived earlier [K. Koga, V. Holten, and B. Widom, J. Phys. Chem. B 119, 13391 (2015)] indicates that if B is asymptotically proportional to a power of σ, the exponent α must be equal to or greater than 6.
- ID情報
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- DOI : 10.1063/5.0097547
- ISSN : 0021-9606
- eISSN : 1089-7690