倉吉健太 (Kenta Kurayoshi) - マイポータル

基本情報

J-GLOBAL ID: 201801005980915107
researchmap会員ID: B000314655

研究分野

論文

Lysine-arginine imbalance overcomes therapeutic tolerance governed by the transcription factor E3-lysosome axis in glioblastoma.

Yongwei Jing, Masahiko Kobayashi, Mahmoud I Shoulkamy, Meiqi Zhou, Ha Thi Vu, Hiroshi Arakawa, Hemragul Sabit, Sadahiro Iwabuchi, Cong Quang Vu, Atsuko Kasahara …

Nature communications 16(1) 2876-2876 2025年4月1日
DEAD/H Box 5 (DDX5) Augments E2F1-Induced Cell Death Independent of the Tumor Suppressor p53

Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Naoyasu Nishimura, Lin Zhao, Mariana Fikriyanti, Yuki Kamiya, Ritsuko Iwanaga, Andrew P. Bradford, Kaori Shinmyozu …

International Journal of Molecular Sciences 25(24) 13251-13251 2024年12月10日
The N-Terminal Region of the Transcription Factor E2F1 Contains a Novel Transactivation Domain and Recruits General Transcription Factor GTF2H2.

Lin Zhao, Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Mariana Fikriyanti, Yuki Kamiya, Hiroyuki Toh, Hideyuki Komori, Ritsuko Iwanaga, Andrew P Bradford …

Biomolecules 14(11) 2024年10月25日
A Supramolecular Biosensor for Rapid and High-Throughput Quantification of a Disease-Associated Niacin Metabolite.

Masaya Ueno, Hiroki Sugiyama, Feng Li, Tatsuya Nishimura, Hiroshi Arakawa, Xi Chen, Xiaoxiao Cheng, Shinji Takeuchi, Yumie Takeshita, Toshinari Takamura …

Analytical chemistry 2024年8月25日
Activation of the CDK7 Gene, Coding for the Catalytic Subunit of the Cyclin-Dependent Kinase (CDK)-Activating Kinase (CAK) and General Transcription Factor II H, by the Trans-Activator Protein Tax of Human T-Cell Leukemia Virus Type-1

Mashiro Shirasawa, Rinka Nakajima, Yaxuan Zhou, Lin Zhao, Mariana Fikriyanti, Ritsuko Iwanaga, Andrew P. Bradford, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani

Genes 15(8) 1080-1080 2024年8月15日
Trans-Activation of the Coactivator-Associated Arginine Methyltransferase 1 (Carm1) Gene by the Oncogene Product Tax of Human T-Cell Leukemia Virus Type 1.

Rahma F Hayati, Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Lin Zhao, Mariana Fikriyanti, Ritsuko Iwanaga, Andrew P Bradford, Kenta Kurayoshi, Keigo Araki …

Genes 15(6) 2024年5月27日
Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression.

Yaxuan Zhou, Rinka Nakajima, Mashiro Shirasawa, Mariana Fikriyanti, Lin Zhao, Ritsuko Iwanaga, Andrew P Bradford, Kenta Kurayoshi, Keigo Araki, Kiyoshi Ohtani

Biology 12(12) 2023年12月11日
Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation.

Kenta Kurayoshi, Yusuke Takase, Masaya Ueno, Kumiko Ohta, Kyoko Fuse, Shuji Ikeda, Takayoshi Watanabe, Yuki Nishida, Shin-Ichi Horike, Kazuyoshi Hosomichi …

Cell death & disease 14(9) 642-642 2023年9月29日査読有り
RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia

Loc Thi Pham, Hui Peng, Masaya Ueno, Susumu Kohno, Atuso Kasada, Kazuyoshi Hosomichi, Takehiro Sato, Kenta Kurayoshi, Masahiko Kobayashi, Yuko Tadokoro …

Biochemical and Biophysical Research Communications 621 74-79 2022年9月査読有り
Therapeutic advantage of targeting lysosomal membrane integrity supported by lysophagy in malignant glioma

Yongwei Jing, Masahiko Kobayashi, Ha Thi Vu, Atsuko Kasahara, Xi Chen, Loc Thi Pham, Kenta Kurayoshi, Yuko Tadokoro, Masaya Ueno, Tomoki Todo …

Cancer Science 113(8) 2716-2726 2022年8月
Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner.

Naho Nomura, Chiaki Ito, Takako Ooshio, Yuko Tadokoro, Susumu Kohno, Masaya Ueno, Masahiko Kobayashi, Atsuko Kasahara, Yusuke Takase, Kenta Kurayoshi …

Scientific reports 11(1) 1666-1666 2021年1月18日
Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples

Masaya Ueno, Takuya Tomita, Hiroshi Arakawa, Takahiro Kakuta, Tada-aki Yamagishi, Jumpei Terakawa, Takiko Daikoku, Shin-ichi Horike, Sha Si, Kenta Kurayoshi …

Communications Chemistry 3(1) 2020年12月
Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes

Hideyuki Komori, Yasuko Goto, Kenta Kurayoshi, Eiko Ozono, Ritsuko Iwanaga, Andrew P. Bradford, Keigo Araki, Kiyoshi Ohtani

Scientific Reports 8(1) 8438 2018年12月1日査読有り
The phosphatidyl inositol 3 kinase pathway does not suppress activation of the ARF and BIM genes by deregulated E2F1 activity

Kenta Kurayoshi, Junko Okuno, Eiko Ozono, Ritsuko Iwanaga, Andrew P. Bradford, Kazuyuki Kugawa, Keigo Araki, Kiyoshi Ohtani

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 482(4) 784-790 2017年1月査読有り
Ectopic expression of the CDK inhibitor p21(Cip1) enhances deregulated E2F activity and increases cancer cell-specific cytotoxic gene expression mediated by the ARF tumor suppressor promoter

Kenta Kurayoshi, Ayumi Shiromoto, Eiko Ozono, Ritsuko Iwanaga, Andrew P. Bradford, Keigo Araki, Kiyoshi Ohtani

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 483(1) 107-114 2017年1月査読有り
Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts

Hodaka Kitamura, Eiko Ozono, Ritsuko Iwanaga, Andrew P. Bradford, Junko Okuno, Emi Shimizu, Kenta Kurayoshi, Kazuyuki Kugawa, Hiroyuki Toh, Kiyoshi Ohtani

GENES TO CELLS 20(9) 739-757 2015年9月査読有り
Cancer cell specific cytotoxic gene expression mediated by ARF tumor suppressor promoter constructs

Kenta Kurayoshi, Eiko Ozono, Ritsuko Iwanaga, Andrew P. Bradford, Hideyuki Komori, Kiyoshi Ohtani

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 450(1) 240-246 2014年7月査読有り

MISC

DDX5 promotes ARF gene expression and apoptosis induced by deregulated E2F1

Kenta Kurayoshi, Kiyoshi Ohtani

CANCER RESEARCH 76 2016年7月

書籍等出版物

Gene Expression and Regulation in Mammalian Cells: The key role of E2F in tumor suppression through specific regulation of tumor suppressor genes specifically in response to oncogenic changes

Kenta Kurayoshi, Eiko Ozono, Ritsuko Iwanaga, Andrew P. Bradford, Hideyuki Komori, Keigo Araki, Kiyoshi Ohtani (担当:共著, 範囲:Chapter 7)

InTech Open Access Publisher 2018年2月
Deregulated E2F Activity: Novel Targets and Therapeutic Potential in Cancer Treatment.

(担当:共著)

International Biology Review 2016年6月

所属学協会

共同研究・競争的資金等の研究課題

リソソーム-鉄経路が規定する白血病幹細胞特異的な遺伝子発現制御機構の特定

日本学術振興会科学研究費助成事業基盤研究(C) 2023年4月 - 2026年3月

倉吉健太
リソソーム代謝経路が規定する白血病幹細胞の未分化性維持機構の解明

日本学術振興会科学研究費助成事業若手研究 2021年4月 - 2023年3月

倉吉健太
ゲノム編集技術を用いた白血病幹細胞の分化制御に関わる因子の同定と機能解析

日本学術振興会科学研究費助成事業若手研究 2019年4月 - 2021年3月

倉吉健太