Kentaro Watanabe

Profile Information

Affiliation: Department of Pediatrics, The University of Tokyo

Degree: 医学博士(Mar, 2021, 東京大学)

Researcher number: 20645006
ORCID ID: https://orcid.org/0000-0003-0868-5289
J-GLOBAL ID: 201901012492809032
Researcher ID: V-9283-2019
researchmap Member ID: B000356063

Research Areas

Major Papers

Inhibition of the galactosyltransferase C1GALT1 reduces osteosarcoma cell proliferation by interfering with ERK signaling and cell cycle progression

Kentaro Watanabe, Keiji Tasaka, Hideto Ogata, Shota Kato, Hiroo Ueno, Katsutsugu Umeda, Tomoya Isobe, Yasuo Kubota, Masahiro Sekiguchi, Shunsuke Kimura …

Cancer Gene Therapy, Apr 15, 2024 Peer-reviewedLead author
Identification of the ultrahigh-risk subgroup in neuroblastoma cases through DNA methylation analysis and its treatment exploiting cancer metabolism.

Kentaro Watanabe, Shunsuke Kimura, Masafumi Seki, Tomoya Isobe, Yasuo Kubota, Masahiro Sekiguchi, Aiko Sato-Otsubo, Mitsuteru Hiwatari, Motohiro Kato, Akira Oka …

Oncogene, 41(46) 4994-5007, Nov 1, 2022 Peer-reviewedLead author
Novel TENM3-ALK fusion is an alternate mechanism for ALK activation in neuroblastoma.

Mitsuteru Hiwatari, Masafumi Seki, Ryosuke Matsuno, Kenichi Yoshida, Takeshi Nagasawa, Aiko Sato-Otsubo, Shohei Yamamoto, Motohiro Kato, Kentaro Watanabe, Masahiro Sekiguchi …

Oncogene, 41(20) 2789-2797, May, 2022 Peer-reviewed
Association of high-risk neuroblastoma classification based on expression profiles with differentiation and metabolism.

Shunsuke Kimura, Masahiro Sekiguchi, Kentaro Watanabe, Mitsuteru Hiwatarai, Masafumi Seki, Kenichi Yoshida, Tomoya Isobe, Yusuke Shiozawa, Hiromichi Suzuki, Noriko Hoshino …

PloS one, 16(1) e0245526, 2021 Peer-reviewed
Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets

Masahiro Sekiguchi, Masafumi Seki, Tomoko Kawai, Kenichi Yoshida, Misa Yoshida, Tomoya Isobe, Noriko Hoshino, Ryota Shirai, Mio Tanaka, Ryota Souzaki …

npj Precision Oncology, 4(1), Dec, 2020 Peer-reviewed
Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets.

Yasuo Kubota, Masafumi Seki, Tomoko Kawai, Tomoya Isobe, Misa Yoshida, Masahiro Sekiguchi, Shunsuke Kimura, Kentaro Watanabe, Aiko Sato-Otsubo, Kenichi Yoshida …

Communications biology, 3(1) 544-544, Sep 30, 2020 Peer-reviewed
DNA methylation-based classification reveals difference between pediatric T-cell acute lymphoblastic leukemia and normal thymocytes.

Shunsuke Kimura, Masafumi Seki, Tomoko Kawai, Hiroaki Goto, Kenichi Yoshida, Tomoya Isobe, Masahiro Sekiguchi, Kentaro Watanabe, Yasuo Kubota, Yasuhito Nannya …

Leukemia, 34(4) 1163-1168, Nov 15, 2019 Peer-reviewed
Management of severe congenital protein C deficiency with a direct oral anticoagulant, edoxaban: A case report

Watanabe K, Arakawa Y, Yanagi M, Isobe K, Mori M, Koh K

Pediatric blood & cancer, 66(6) e27686, Jun, 2019 Peer-reviewedLead author
Unrelated allogeneic hematopoietic stem cell transplantation in a patient with Revesz syndrome, a severe variant of dyskeratosis congenita

Kentaro Watanabe, Yuki Arakawa, Tomoka Kambe, Eiji Oguma, Hiroshi Kishimoto, Katsuyoshi Koh

Pediatric Blood & Cancer, 66(1) e27476, Sep, 2018 Peer-reviewedLead author
Characteristics of methotrexate-induced stroke-like neurotoxicity

Kentaro Watanabe, Yuki Arakawa, Eiji Oguma, Taichi Uehara, Masato Yanagi, Chigusa Oyama, Yuhachi Ikeda, Koji Sasaki, Kiyotaka Isobe, Makiko Mori …

International Journal of Hematology, 108(6) 630-636, Sep, 2018 Peer-reviewedLead author
Perioperative management of severe congenital protein C deficiency

Kentaro Watanabe, Motohiro Kato, Tetsuya Ishimaru, Mitsuteru Hiwatari, Tomonori Suzuki, Yoshihiro Minosaki, Junko Takita, Jun Fujishiro, Akira Oka

Blood Coagulation and Fibrinolysis, 28(8) 646-649, Dec 1, 2017 Peer-reviewedLead author
Cyclophosphamide―associated cardiomyopathy after allogeneic hematopoietic stem cell transplantation from a sibling donor for refractory cytopenia of childhood

渡邉健太郎, 加藤元博, 田中淳, 中井まりえ, 関正史, 林泰佑, 塩澤亮輔, 樋渡光輝, 吉田健一, 小川誠司 …

日本造血細胞移植学会雑誌(Web), 3(4) 120-123 (J-STAGE)-123, 2014 Peer-reviewedLead author

Research Projects

「がん代謝」を標的とする薬剤と抗がん剤を併用した、神経芽腫の新規治療法の創出

科学研究費助成事業若手研究, 若手研究, 日本学術振興会, Apr, 2022 - Mar, 2024

渡邉健太郎
「がん代謝」を標的とした、神経芽腫に対する新規治療の創出と抵抗性の克服

科学研究費助成事業研究活動スタート支援, 研究活動スタート支援, 日本学術振興会, Aug, 2021 - Mar, 2023

渡邉健太郎
Multiomics analysis of neuroblastoma searching for novel therapies

Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows, Grant-in-Aid for JSPS Fellows, Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2021