樋口公嗣 (Koji Higuchi) - マイポータル

基本情報

J-GLOBAL ID: 202301003698739395
researchmap会員ID: R000053461

論文

The Kagoshima-DVT Score Is a Useful Predictive Model for Cancer-Associated Thrombosis in Patients With Gastrointestinal Cancer.

Keisuke Shibata, Akihiro Tokushige, Yuki Hamamoto, Koji Higuchi, Masakazu Imamura, Yoshiyuki Ikeda, Mitsuru Ohishi

Circulation reports 5(2) 19-26 2023年2月10日
Hypertension, cardiovascular disease, and nocturia: a systematic review of the pathophysiological mechanisms.

Mitsuru Ohishi, Takuro Kubozono, Koji Higuchi, Yuichi Akasaki

Hypertension research : official journal of the Japanese Society of Hypertension 44(7) 733-739 2021年7月
Fabry disease.

Toshinori Yuasa, Toshihiro Takenaka, Koji Higuchi, Nami Uchiyama, Yoshihisa Horizoe, Hideto Cyaen, Naoko Mizukami, Kunitsugu Takasaki, Akira Kisanuki, Masaaki Miyata …

Journal of echocardiography 15(4) 151-157 2017年12月
Prevalence and clinical features of Fabry disease in Japanese male patients with diagnosis of hypertrophic cardiomyopathy.

Toru Kubo, Yuri Ochi, Yuichi Baba, Takayoshi Hirota, Katsutoshi Tanioka, Naohito Yamasaki, Makoto Yoshimitsu, Koji Higuchi, Toshihiro Takenaka, Kimiko Nakajima …

Journal of cardiology 69(1) 302-307 2017年1月
Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism.

Mayumi Nakahara, Takashi Ito, Ko-ichi Kawahara, Mika Yamamoto, Tomoka Nagasato, Binita Shrestha, Shingo Yamada, Takahiro Miyauchi, Koji Higuchi, Toshihiro Takenaka …

PloS one 8(9) e75961 2013年
Neonatal transfer of membrane-bound stem cell factor improves survival and heart function in aged mice after myocardial ischemia.

Zhuo Sun, Chyan-Jang Lee, Salvador Mejia-Guerrero, Yuemei Zhang, Koji Higuchi, Ren-Ke Li, Jeffrey A Medin

Human gene therapy 23(12) 1280-9 2012年12月
Sequencing and characterization of the porcine α-galactosidase A gene: towards the generation of a porcine model for Fabry disease.

Makoto Yoshimitsu, Koji Higuchi, Xin Fan, Sonshin Takao, Jeffrey A Medin, Chuwa Tei, Toshihiro Takenaka

Molecular biology reports 38(5) 3145-52 2011年6月
Identification of novel mutations in the α-galactosidase A gene in patients with Fabry disease: pitfalls of mutation analyses in patients with low α-galactosidase A activity.

Makoto Yoshimitsu, Koji Higuchi, Masaaki Miyata, Sean Devine, Andre Mattman, Sandra Sirrs, Jeffrey A Medin, Chuwa Tei, Toshihiro Takenaka

Journal of cardiology 57(3) 345-53 2011年5月
Alpha-galactosidase A-Tat fusion enhances storage reduction in hearts and kidneys of Fabry mice.

Koji Higuchi, Makoto Yoshimitsu, Xin Fan, Xiaoxin Guo, Vanessa I Rasaiah, Jennifer Yen, Chuwa Tei, Toshihiro Takenaka, Jeffrey A Medin

Molecular medicine (Cambridge, Mass.) 16(5-6) 216-21 2010年
Vascular endothelial growth factor broadens lentivector distribution in the heart after neonatal injection.

Takeya Sato, Shobha Ramsubir, Koji Higuchi, Teruyuki Yanagisawa, Jeffrey A Medin

Journal of cardiology 54(2) 245-54 2009年10月
Direct injection of kit ligand-2 lentivirus improves cardiac repair and rescues mice post-myocardial infarction.

Koji Higuchi, Bilal Ayach, Takeya Sato, Manyin Chen, Sean P Devine, Vanessa I Rasaiah, Fayez Dawood, Teruyuki Yanagisawa, Chuwa Tei, Toshihiro Takenaka …

Molecular therapy : the journal of the American Society of Gene Therapy 17(2) 262-8 2009年2月
Terminal stage cardiac findings in patients with cardiac Fabry disease: an electrocardiographic, echocardiographic, and autopsy study.

Toshihiro Takenaka, Hiroyuki Teraguchi, Aichi Yoshida, Syuhei Taguchi, Kenjiro Ninomiya, Yoshihisa Umekita, Hiroki Yoshida, Michiko Horinouchi, Kazuhiro Tabata, Suguru Yonezawa …

Journal of cardiology 51(1) 50-9 2008年2月
Efficient correction of Fabry mice and patient cells mediated by lentiviral transduction of hematopoietic stem/progenitor cells.

M Yoshimitsu, K Higuchi, S Ramsubir, T Nonaka, V I Rasaiah, C Siatskas, S-B Liang, G J Murray, R O Brady, J A Medin

Gene therapy 14(3) 256-65 2007年2月
Lentiviral vectors for gene therapy of heart disease.

Koji Higuchi, Jeffrey A Medin

Journal of cardiology 49(1) 1-11 2007年1月
Correction of cardiac abnormalities in fabry mice by direct intraventricular injection of a recombinant lentiviral vector that engineers expression of alpha-galactosidase A.

Makoto Yoshimitsu, Koji Higuchi, Fayez Dawood, Vanessa I Rasaiah, Bilal Ayach, Manyin Chen, Peter Liu, Jeffrey A Medin

Circulation journal : official journal of the Japanese Circulation Society 70(11) 1503-8 2006年11月
Stem cell factor receptor induces progenitor and natural killer cell-mediated cardiac survival and repair after myocardial infarction.

Bilal B Ayach, Makoto Yoshimitsu, Fayez Dawood, Mei Sun, Sara Arab, Manyin Chen, Koji Higuchi, Christopher Siatskas, Paul Lee, Hilda Lim …

Proceedings of the National Academy of Sciences of the United States of America 103(7) 2304-9 2006年2月14日
[Usefulness of rapid quantitative cardiac troponin T and myoglobin assays for the diagnosis of acute myocardial infarction].

Koji Higuchi, Satoshi Abe, Tatsuru Matsuoka, Hitoshi Nakajima, Hitoshi Toda, Yuichi Akasaki, Hiroyuki Torii, Sou Kuwahata, Yoshihiko Atsuchi, Koshi Mawatari …

Journal of cardiology 41(2) 55-62 2003年2月

MISC

VEGF increases lentivector distribution after neonatal injection

Takeya Sato, Shobha Ramsubir, Koji Higuchi, Jeffrey Medin, Teruyuki Yanagisawa

JOURNAL OF PHARMACOLOGICAL SCIENCES 112 128P-128P 2010年

共同研究・競争的資金等の研究課題

血漿および白血球中αガラクトシダーゼ活性相違の検討

日本学術振興会科学研究費助成事業基盤研究(C) 2022年4月 - 2025年3月

樋口公嗣
Fabry病の新規αガラクトシダーゼ遺伝子変異による酵素の生体内動態に関する研究

日本学術振興会科学研究費助成事業基盤研究(C) 2017年4月 - 2021年3月

樋口公嗣, 吉満誠
ファブリー病に対する遺伝子治療:ミニブタを用いた検討

日本学術振興会科学研究費助成事業基盤研究(C) 2010年 - 2012年

竹中俊宏, 樋口公嗣, 吉満誠
レンチベクターを用いたkit ligandによる心筋梗塞に対する遺伝子治療

日本学術振興会科学研究費助成事業若手研究(B) 2010年 - 2011年

樋口公嗣