Kazuki Horikawa

Profile Information

Affiliation: 教授, 先端研究推進センターバイオイメージング研究部門, 徳島大学

Researcher number: 70420247
J-GLOBAL ID: 202001009455411169
researchmap Member ID: R000005835

Research Interests

Research Areas

Research History

Apr, 2020 - Present

教授, 先端研究推進センター, 徳島大学
Apr, 2015 - Mar, 2020

教授, 医歯薬学研究部, 徳島大学大学院
Oct, 2014 - Mar, 2015

教授, HBS研究部, 徳島大学大学院
Jun, 2012 - Sep, 2014

特任教授, HBS研究部, 徳島大学大学院
Oct, 2010 - May, 2012

准教授, 新分野創造センター, 国立遺伝学研究所
Dec, 2006 - Sep, 2010

特任准教授, ニコンバイオイメージングセンター, 北海道大学電子科学研究所
Oct, 2006 - Mar, 2010

兼任研究員, 戦略的創造研究推進事業さきがけ
Sep, 2005 - Sep, 2006

助手, 理学研究科, 東京大学大学院
Apr, 2002 - Aug, 2005

研究員,特別研究員PD,助手, 理学研究科, 東京大学大学院

Education

Apr, 1999 - Mar, 2002

生物物理学専攻修士後期課程, 理学研究科, 京都大学
Apr, 1997 - Mar, 1999

生物物理学専攻修士前期課程, 理学研究科, 京都大学
Apr, 1993 - Mar, 1997

理学部, 京都大学

Papers

Mesoscale heterogeneity is a critical determinant for spiral pattern formation in developing social amoeba

Taishi Kakizuka, Hidenori Nakaoka, Yusuke Hara, Aya Ichiraku, Yoshiyuki Arai, Hiroya Itoga, Shuichi Onami, Taro Ichimura, Takeharu Nagai, Kazuki Horikawa

Scientific Reports, 15(1), Jan 9, 2025
High-affinity tuning of single fluorescent protein-type indicators by flexible linker length optimization in topology mutant

Yusuke Hara, Aya Ichiraku, Tomoki Matsuda, Ayuko Sakane, Takuya Sasaki, Takeharu Nagai, Kazuki Horikawa

Communications Biology, 7(1), Jun 8, 2024
Strength in numbers: Unleashing the potential of trans-scale scope AMATERAS for massive cell quantification

Taro Ichimura, Taishi Kakizuka, Yuki Sato, Yoichiro Fujioka, Yusuke Ohba, Kazuki Horikawa, Takeharu Nagai

Biophysics and Physicobiology, 2024
Comparison of particle image velocimetry and the underlying agents dynamics in collectively moving self propelled particles.

Udoy S Basak, Sulimon Sattari, Md Motaleb Hossain, Kazuki Horikawa, Mikito Toda, Tamiki Komatsuzaki

Scientific reports, 13(1) 12566-12566, Aug 2, 2023
Live Imaging of cAMP Signaling in D. discoideum Based on a Bioluminescent Indicator, Nano-lantern (cAMP)

Kazuki Horikawa, Takeharu Nagai

cAMP Signaling, 231-240, Mar 12, 2022
JRAB/MICAL-L2 undergoes liquid–liquid phase separation to form tubular recycling endosomes

Ayuko Sakane, Taka-aki Yano, Takayuki Uchihashi, Kazuki Horikawa, Yusuke Hara, Issei Imoto, Shusaku Kurisu, Hiroshi Yamada, Kohji Takei, Takuya Sasaki

Communications Biology, 4(1), Dec, 2021
Exploring rare cellular activity in more than one million cells by a transscale scope

T. Ichimura, T. Kakizuka, K. Horikawa, K. Seiriki, A. Kasai, H. Hashimoto, K. Fujita, T. M. Watanabe, T. Nagai

Scientific Reports, 11(1) 16539, Aug 8, 2021 Peer-reviewed
Design and synthesis of gene-directed caged cyclic nucleotides exhibiting cell type selectivity

Akinobu Z. Suzuki, Taichi Sakano, Hirona Sasaki, Rei Watahiki, Masaki Sone, Kazuki Horikawa, Toshiaki Furuta

CHEMICAL COMMUNICATIONS, 57(46) 5630-5633, Jun, 2021
An information-theoretic approach to infer the underlying interaction domain among elements from finite length trajectories in a noisy environment

Udoy S. Basak, Sulimon Sattari, Md. Motaleb Hossain, Kazuki Horikawa, Tamiki Komatsuzaki

The Journal of Chemical Physics, 154(3) 034901-034901, Jan 21, 2021
Transfer entropy dependent on distance among agents in quantifying leader-follower relationships.

Udoy S Basak, Sulimon Sattari, Motaleb Hossain, Kazuki Horikawa, Tamiki Komatsuzaki

Biophysics and physicobiology, 18 131-144, 2021
Inferring domain of interactions among particles from ensemble of trajectories

Udoy S. Basak, Sulimon Sattari, Kazuki Horikawa, Tamiki Komatsuzaki

Physical Review E, 102(1) 012404-012404, Jul 9, 2020 Peer-reviewed
Cellular logics bringing the symmetry breaking in spiral nucleation revealed by trans-scale imaging

Taishi Kakizuka, Yusuke Hara, Yusaku Ohta, Asuka Mukai, Aya Ichiraku, Yoshiyuki Arai, Taro Ichimura, Takeharu Nagai, Kazuki Horikawa

bioRxiv, Jun 29, 2020
Trans-scale-scope to find rare cellular activity in sub-million cells.

Ichimura T, Kakizuka T, Horikawa K, Seiriki K, Kasai A, Hashimoto H, Fujita K, Watanabe TM, Nagai T

bioRxiv,, 2020
Red fluorescent cAMP indicator with increased affinity and expanded dynamic range.

Yusaku Ohta, Toshiaki Furuta, Takeharu Nagai, Kazuki Horikawa

Scientific reports, 8(1) 1866-1866, Jan 30, 2018 Peer-reviewed
Cardiomyocytes cultured on mechanically compliant substrates

Morishima M, Horikawa K, Funaki M

PLOS ONE, 13(8) 1-19, 2018 Peer-reviewed
Conformational plasticity of JRAB/MICAL-L2 provides "law and order" in collective cell migration

Ayuko Sakane, Shin Yoshizawa, Masaomi Nishimura, Yuko Tsuchiya, Natsuki Matsushita, Kazuhisa Miyake, Kazuki Horikawa, Issei Imoto, Chiharu Mizuguchi, Hiroyuki Saito …

Molecular Biology of the Cell, 27(20) 3095-3108, Oct 15, 2016 Peer-reviewed
Nontrivial Effect of the Color-Exchange of a Donor/Acceptor Pair in the Engineering of Förster Resonance Energy Transfer (FRET)-Based Indicators.

Yusaku Ohta, Takanori Kamagata, Asuka Mukai, Shinji Takada, Takeharu Nagai, Kazuki Horikawa

ACS chemical biology, 11(7) 1816-22, Jul 15, 2016 Peer-reviewed
Reliable handling of highly A/T-rich genomic DNA for efficient generation of knockin strains of Dictyostelium discoideum.

Asuka Mukai, Aya Ichiraku, Kazuki Horikawa

BMC biotechnology, 16 37-37, Apr 14, 2016 Peer-reviewed
Identification of polyethylene glycol-resistant macrophages on stealth imaging in vitro using fluorescent organosilica nanoparticles

Michihiro Nakamura, Koichiro Hayashi, Mutsuki Nakano, Takafumi Kanadani, Kazue Miyamoto, Toshinari Kori, Kazuki Horikawa

ACS Nano, 9(2) 1058-1071, Feb 24, 2015 Peer-reviewed
Effective impairment of myeloma cells and their progenitors by blockade of monocarboxylate transportation

Derek James Hanson, Shingen Nakamura, Ryota Amachi, Masahiro Hiasa, Asuka Oda, Daisuke Tsuji, Kohji Itoh, Takeshi Harada, Kazuki Horikawa, Jumpei Teramachi …

Oncotarget, 6(32) 33568-33586, 2015 Peer-reviewed
Recent progress in the development of genetically encoded Ca2+ indicators.

Kazuki Horikawa

The journal of medical investigation : JMI, 62(1-2) 24-8, 2015 Peer-reviewed
In vivo visualization of subtle, transient, and local activity of astrocytes using an ultrasensitive Ca(2+) indicator.

Kazunori Kanemaru, Hiroshi Sekiya, Ming Xu, Kaname Satoh, Nami Kitajima, Keitaro Yoshida, Yohei Okubo, Takuya Sasaki, Satoru Moritoh, Hidetoshi Hasuwa …

Cell reports, 8(1) 311-8, Jul 10, 2014 Peer-reviewed
Fluoresecet probes for bio-imaging of bone.

K.Horikawa

The Bone, 28(2), 2014 Peer-reviewed
Genetically encoded Ca(2+) indicators; expanded affinity range, color hue and compatibility with optogenetics.

Takeharu Nagai, Kazuki Horikawa, Kenta Saito, Tomoki Matsuda

Frontiers in molecular neuroscience, 7 90-90, 2014 Peer-reviewed
[Spatiotemporal regulation of Ca(2 +) dynamics in live cells revealed by Ca(2 +) imaging].

Kazuki Horikawa, Takeharu Nagai

Clinical calcium, 23(4) 527-533, Apr, 2013 Peer-reviewed
Ca2+イメージングで解き明かすCa2+動態の時空間統御機構

堀川一樹, 永井健治

CLINICAL CALCIUM -循環器疾患とカルシウム・リン,, 23(4), 2013 Peer-reviewed
Highlighted Ca²⁺ imaging with a genetically encoded 'caged' indicator.

Tomoki Matsuda, Kazuki Horikawa, Kenta Saito, Takeharu Nagai

Scientific reports, 3 1398-1398, 2013 Peer-reviewed
Mcm8 and Mcm9 Form a Complex that Functions in Homologous Recombination Repair Induced by DNA Interstrand Crosslinks

Kohei Nishimura, Masamichi Ishiai, Kazuki Horikawa, Tatsuo Fukagawa, Minoru Takata, Haruhiko Takisawa, Masato T. Kanemaki

Molecular Cell, 47(4) 511-522, Aug 24, 2012 Peer-reviewed
Luminescent proteins for high-speed single-cell and whole-body imaging.

Kenta Saito, Y-F Chang, Kazuki Horikawa, Noriyuki Hatsugai, Yuriko Higuchi, Mitsuru Hashida, Yu Yoshida, Tomoki Matsuda, Yoshiyuki Arai, Takeharu Nagai

Nature communications, 3 1262-1262, 2012 Peer-reviewed
Development of ultra-sensitive Ca2+indicators, yellow cameleon-nanos

Takeharu Nagai, Kazuki Horikawa, Tomoki Matsuda, Kentaro Kobayashi

Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications III, Feb 10, 2011 Peer-reviewed
機能イメージングにおける指示薬感度の重要性

永井健治, 堀川一樹

蛍光イメージング/ MRIプローブの開発 2011年9月号, 44(50), 2011 Peer-reviewed
バイオイメージング細胞間シグナルの伝達パターンを捉える

堀川一樹, 永井健治

細胞性粘菌の集合流形成,、生物の遺伝。2011年9月号, 87-91, 2011 Peer-reviewed
Quantitative Comparison of Genetically Encoded Ca2+ Indicators in Cortical Pyramidal Cells and Cerebellar Purkinje Cells.

Y.Yamada, T.Michikawa, M.Hashimoto, K.Horikawa, T.Nagai, A.Miyawaki, M.Häusser, K. Mikoshiba

Front Cell NeuroSci., 5 18-19, 2011 Peer-reviewed
Spontaneous network activity visualized by ultrasensitive Ca(2+) indicators, yellow Cameleon-Nano.

Kazuki Horikawa, Yoshiyuki Yamada, Tomoki Matsuda, Kentarou Kobayashi, Mitsuhiro Hashimoto, Toru Matsu-ura, Atsushi Miyawaki, Takayuki Michikawa, Katsuhiko Mikoshiba, Takeharu Nagai

Nature methods, 7(9) 729-32, Sep, 2010 Peer-reviewed
Auto-luminescent genetically-encoded ratiometric indicator for real-time Ca2+ imaging at the single cell level.

Kenta Saito, Noriyuki Hatsugai, Kazuki Horikawa, Kentaro Kobayashi, Toru Matsu-Ura, Katsuhiko Mikoshiba, Takeharu Nagai

PloS one, 5(4) e9935, Apr 1, 2010 Peer-reviewed
1P327 A genetically-encoded autoluminescent Ca2+ indicators with expanded dynamic range(Bioimaging,The 48th Annual Meeting of the Biophysical Society of Japan)

Chang Yu-Fen, Saito Kenta, Horikawa Kazuki, Matsuda Tomoki, Nagai Takeharu

Seibutsu Butsuri, 50(2) S77, 2010
[Ultra-sensitive and large-scale imaging of cellular coupled oscillator systems].

Kazuki Horikawa, Takeharu Nagai

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 54(15) 1945-1951, Dec, 2009 Peer-reviewed
Functional role of a specialized class of spinal commissural inhibitory neurons during fast escapes in zebrafish.

Chie Satou, Yukiko Kimura, Tsunehiko Kohashi, Kazuki Horikawa, Hiroyuki Takeda, Yoichi Oda, Shin-ichi Higashijima

The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(21) 6780-93, May 27, 2009 Peer-reviewed
An ultramarine fluorescent protein with increased photostability and pH insensitivity.

Wataru Tomosugi, Tomoki Matsuda, Tomomi Tani, Tomomi Nemoto, Ippei Kotera, Kenta Saito, Kazuki Horikawa, Takeharu Nagai

Nature methods, 6(5) 351-3, May, 2009 Peer-reviewed
Auditory input to CNS is acquired coincidentally with development of inner ear after formation of functional afferent pathway in zebrafish

Masashi Tanimoto, Yukiko Ota, Kazuki Horikawa, Yoichi Oda

Journal of Neuroscience, 29(9) 2762-2767, Mar 4, 2009 Peer-reviewed
2P-269 Long time physiological imaging of plant cells with reduced autofluorescence by using a Ca^<2+> indicator composed of a red- shifted FRET pair(Bioimaging,The 47th Annual Meeting of the Biophysical Society of Japan)

Uematsu Toshiaki, Kotera Ippei, Saito Kenta, Hatsugai Noriyuki, Horikawa Kazuki, Nagai Takeharu

Seibutsu Butsuri, 49 S149, 2009
細胞結合振動子システムを対象にした超高感度大規模イメージング

堀川一樹, 永井健治

蛋白質核酸酵素2009 12月号, 1945-1951, 2009 Peer-reviewed
2P-341 An ultramarine fluorescent protein with stable photostability and no pH sensitivity(The 46th Annual Meeting of the Biophysical Society of Japan)

Tomosugi Wataru, Matsuda Tomoki, Kotera Ippei, Saito Kenta, Horikawa Kazuki, Nagai Takeharu

Seibutsu Butsuri, 48 S127, 2008
生物のパターン形成に使われる振動子集団が示す強力なノイズ耐性

石松愛, 堀川一樹

生物物理, 48(2) 20-26, 2008 Peer-reviewed
Insertional mutagenesis by the Tol2 transposon-mediated enhancer trap approach generated mutations in two developmental genes: tcf7 and synembryn-like.

Saori Nagayoshi, Eriko Hayashi, Gembu Abe, Naoki Osato, Kazuhide Asakawa, Akihiro Urasaki, Kazuki Horikawa, Kazuho Ikeo, Hiroyuki Takeda, Koichi Kawakami

Development (Cambridge, England), 135(1) 159-69, Jan, 2008 Peer-reviewed
Coupling cellular oscillators: a mechanism that maintains synchrony against developmental noise in the segmentation clock.

Kana Ishimatsu, Kazuki Horikawa, Hiroyuki Takeda

Developmental dynamics : an official publication of the American Association of Anatomists, 236(6) 1416-1421, Jun, 2007 Peer-reviewed
[Basic principle of the segmentation clock: synchronization and robustness to noise].

Hiroyuki Takeda, Kazuki Horikawa

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 52(3) 236-42, Mar, 2007 Peer-reviewed
分節時計が正確に時を刻むメカニズム——同調性とノイズ耐性蛋白質

堀川一樹, 武田洋幸

核酸酵素, 152(3) 236-242, 2007 Peer-reviewed
分節振動体がノイズの影響を緩和する機構

石松愛, 武田洋幸, 堀川一樹

時間生物学, 13(1) 20-26, 2007 Peer-reviewed
Noise-resistant and synchronized oscillation of the segmentation clock.

Kazuki Horikawa, Kana Ishimatsu, Eiichi Yoshimoto, Shigeru Kondo, Hiroyuki Takeda

Nature, 441(7094) 719-23, Jun 8, 2006 Peer-reviewed
生物時計と体節形成―時間細胞の同調メカニズム

堀川一樹, 武田洋幸

バイオニクス2006 9月号, 3(9) 32-38, 2006 Peer-reviewed
分節時計のノイズ解消機構

堀川一樹, 武田洋幸

細胞工学, 125(11) 1300-1305, 2006 Peer-reviewed
数理と生物学の融合への想い─生物時計の研究から

堀川一樹

科学, 76(11) 1075-1077, 2006 Peer-reviewed
Requirement of the juxtamembrane domain of the cadherin cytoplasmic tail for morphogenetic cell rearrangement during myotome development.

K.Horikawa, M.Takeichi

J. Cell Biol., 155 1297, 2006 Peer-reviewed
Requirement of the juxtamembrane domain of the cadherin cytoplasmic tail for morphogenetic cell rearrangement during myotome development

Kazuki Horikawa, Masatoshi Takeichi

Journal of Cell Biology, 155(7) 1297-1306, Dec 24, 2001 Peer-reviewed
Adhesive subdivisions intrinsic to the epithelial somites.

K.Horikawa, G.Radice, M.Takeichi, O.Chisaka

Dev. Biol, 215 182, 1999 Peer-reviewed

Misc.

Transfer entropy dependent on distance among agents in quantifying leader-follower relationships

Udoy S. Basak, Sulimon Sattari, Motaleb Hossain, Kazuki Horikawa, Tamiki Komatsuzaki

BIOPHYSICS AND PHYSICOBIOLOGY, 18 131-144, 2021
Real time imaging of biological phenomena with super-duper luminescent proteins

Kenta Saito, Yu-Fen Chang, Kazuki Horikawa, Yuriko Higuchi, Mitsuru Hashida, Tomoki Matsuda, Yoshiyuki Arai, Takeharu Nagai

Cytologia, 80(1) 2, 2015
生体組織内の1細胞レベルでの機能イメージングを可能にする光活性化型生理機能プローブ

松田知己, 堀川一樹, 永井健治

バイオイメージング, 20(2) 185-186, Aug 10, 2011
Auditory input to CNS is acquired coincidentally with development of inner ear after formation of functional afferent pathway in zebrafish

Masashi Tanimoto, Yukiko Ota, Kazuki Horikawa, Yoichi Oda

NEUROSCIENCE RESEARCH, 65 S69-S69, 2009
AUDITORY INPUT TO CNS IS ACQUIRED COINCIDENT WITH FUNCTIONAL DEVELOPMENT OF INNER EAR AFTER FORMATION OF AFFERENT PATHWAY IN ZEBRAFISH

Masashi Tanimoto, Yukiko Ota, Kazuki Horikawa, Yoichi Oda

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 338-338, 2009
Quantitative analysis of developmental processes of following behaviors in medaka using a newly established assay system

Haruka Imada, Kenichi Shirai, Yuuji Suehiro, Kazuki Horikawa, Atsuko Shimada, Kiyoshi Naruse, Hiroyuki Takeda, Takeo Kubo, Hideaki Takeuchi

ZOOLOGICAL SCIENCE, 23(12) 1187-1187, Dec, 2006
Analysis of mathematical principle of information processing and the molecular/neural basis that underlie optomotor response of small fishes

Yuuji Suehiro, Haruka Imada, Kazuki Horikawa, Atsuko Shimada, Kiyoshi Naruse, Hiroyuki Takeda, Takeo Kubo, Hideaki Takeuchi

ZOOLOGICAL SCIENCE, 23(12) 1187-1187, Dec, 2006

Books and Other Publications

蛍光タンパク質 ⅳ.cAMPプローブ,生きてるものは全部観る！イメージングの選び方・使い方100＋

堀川一樹

羊土社, 2018
How Low Can You Go? The Numbers of Cells That Make Up Bodies: Large Numbers and Small Numbers,Minorities and Small Numbers from Molecules to Organisms in Biology-Toward a New Understanding of Biological Phenomena,

Kazuki Horikawa

Springer, 2018
少数生物学

永井健治, 村越秀治, 大場雄介, 冨樫祐一, 小松崎民生, 城口克之, 野地博行, 前島一博, 粟津暁紀, 鈴木宏明, 茅元司, 矢島潤一郎, 谷口雄一, 小嶋誠司, 今田勝己, 石島秋彦, 福岡創, 葵栄淑, 堀川一樹, 大出晃士, 上田泰己

日本論評社, 2017
細胞集団シグナル伝達の少数制御、少数性生物ってなんだ？少数の因子が生命システムを制御する

堀川一樹, 太田裕作, 向井あすか, 新井由之, 永井健治

羊土社, 2017
細胞結合振動子システムを対象にした超高感度大規模イメージング

堀川一樹, 永井健治

共立出版, 2009
生物時計と体節形成―時間細胞の同調メカニズム

堀川一樹, 武田洋幸

バイオニクス2006 9月号, 2006

Presentations

“Singularity Biology : small elements change the function of the systems”

K.Horikawa

2019
大規模イメージングで明らかになった、cAMP信号波の螺旋コア形成機構

堀川一樹

第42回日本分子生物学会, 2019
新規赤色 cAMP 指示薬の開発と応用

堀川一樹

日本蛋白質科学会第18回年会, 2018
階層横断的イメージングで明らかになったシグナル伝達動態の自発的対称性破れ機構

堀川一樹

生命科学系学会合同年次大会（ConBio2017）, 2017
細胞集団に螺旋信号波をもたらす臨界現象

堀川一樹

日本生物物理学会第55回年会, 2017
１分子から個体レベルまでの多階層バイオイメージング

堀川一樹

日本学術会議公開シンポジウム, 2017
自発的発振回路の新規構築原理

堀川一樹

日本顕微鏡学会第71回学術講演会, 2015
Minority control of synchronized dynamics in biological oscillator.

2015
Chemical Sensing Mechanism of Collective Cell Migration

2014
徳島大学バイオイメージングプラットフォームについて

堀川一樹

第1回バイオイメージングフォーラム, 2014
生理機能を可視化する蛍光プローブの開発

堀川一樹

日本再生歯科医学会教育講演, 2014
光イメーシンクによる生体機能への横断的アフローチ

堀川一樹

第35回日本生理学会シンポジウム, 2014
蛍光イメージングの新基軸

堀川一樹

第55回日本生化学会シンポジウム, 2014
Beyond Live cell imaging

2013
Novel strategy and thinking

2012
Dynamics of social behabior in biology

2012
ライブイメージングのための高性能指示薬の研究および開発

堀川一樹

第2回日本粘菌学会, 2012
ライブイメージングのための高性能指示薬の開発

堀川一樹

第35回日本分子生物学会, 2012
Neuronal ensemble revealed by calcium imaging, “Spontaneous network activity visualized by ultrasensitive Ca2+ indicators, yellow Cameleon- Nano”

2011
Constructive role of noise in the self-organized pattern formation of social amoeba

2010
自己組織的パターン形成過程を定量するためのプローブ開発とその応用

堀川一樹

定量生物学会, 2010
発生ダイナミクスの多次元的プロファイリング, “Large-sclacle imaging of biological rhythms inmulticellular network”

堀川一樹

日本生化学会シンポジウム, 2009
自己組織的パターン形成における揺らぎの役割

堀川一樹

日本発生生物学会秋季シンポジウム, 2009
Research on noise reduction mechanism in multi-cell coupled oscillator

2008
Noise reduction mechniasm in multicellular coupled oscillator

2008
Visualization of noise and its reduction mechanism in living coupled oscillator systems”

堀川一樹

2008
Vertebrate axis formation: Translation of temporal and spatial information, “How does the developmental system reduce the effect of noise? -A case study in the segmentation clock-”

2006

Professional Memberships

Apr, 2014 - Present

日本生化学会 (正会員)

Research Projects

Analysis of the singularity cells controlling the pattern formation of multicellular system

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2018 - Mar, 2023
Novel mechanism of chronic inflammation in progression and destabilization of atherosclerotic plaque

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

SATA Masataka
Molecular mechanisms translating the pulse information into developmental time

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2019
Single molecule analysis in the generation of oscillatory circuit for cAMP signaling

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2017

HORIKAWA Kazuki
Visualization of chronic inflammation in arterial wall and perivascular adipose tissue

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

SATA Masataka, HORIKAWA Kazuki, FUKUDA Daiju, HIGASHIKUNI Yasutomi, SATOMI Junichi, NAKAYAMA Taisuke
Spying minority in biological phenomena -Toward bridging dynamics between individual and ensemble processes-

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2016

Nagai Takeharu, UEDA HIROK, ISHIJIMA AKIHIKO, IMADA KATSUMI, MAESHIMA KAZUHIRO, NOJI HIROYUKI, TOGASHI YUICHI, ARAI YOSHIYUKI, MATSUDA TOMOKI, YOSHIMURA SHIGEHIRO, HORIKAWA KAZUKI, WATANABE TOMONOBU, FUJITA KATSUMASA, KINBARA KAZUSHI, SANDO SHINSUKE, TAKEUCHI SHOJI, KOMATSUZAKI TAMIKI, OKADA YASUSHI, HARADA YOSHIE
Development of molecular probes and photo manipulation tools - Technologies for visualization and control of small number of biomolecules

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2016

Nagai Takeharu, KINNBARA KAZUSHI, HORIKAWA KAZUKI, SANDO SHINSUKE, URANO YASUTERU, OZAWA TAKEAKI, MATSUDA TOMOKI, ARAI YOSHIYUKI
マクロファージの異常な活性化に起因する慢性炎症発症機序の解明

科学研究費助成事業新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2013 - Mar, 2015

堀川一樹
in vivo imaging analysis of cGMP dynamics in the smooth muscle of circulatory system

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2015

HORIKAWA Kazuki
多細胞社会の秩序形成を司る細胞個性のマルチスケール定量と操作

科学研究費助成事業新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2011 - Mar, 2013

堀川一樹
Development of multi-scale and functional imaging technique to quantify the fluctuation in intercellular signaling

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, 2010 - 2011

HORIKAWA Kazuki
相互作用に支配される細胞集団の協調的振る舞い

科学技術振興機構さきがけ研究, Apr, 2006 - Mar, 2010

堀川一樹
Elucidation of self-organization process in living organism by small number of molecules using functional imaging

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (A), Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, 2006 - 2008

NAGAI Takeharu, TANI Tomomi, HORIKAWA Kazuki
エンハンサートラップ法とライブイメージングを軸とした聴覚システム発生機構の研究

科学研究費助成事業若手研究(スタートアップ), 若手研究(スタートアップ), 日本学術振興会, 2006 - 2007

堀川一樹
ライブイメージングを利用した体節の分節化・上皮化機構の研究

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, 2003 - 2005

堀川一樹
体節のパターン形成における上皮⇔間充織転換機構

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, 1999 - 2001

堀川一樹

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