2022
Intramolecular G-quadruplex-hairpin loop structure competition of a GC-rich exon region in the TMPRSS2 gene
Chemical Communications
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- Volume
- 58
- Number
- 1
- First page
- 48
- Last page
- 51
- Language
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1039/d1cc05523b
- Publisher
- Royal Society of Chemistry (RSC)
We identified cytosine-rich regions adjacent to guanine-rich regions in the TMPRSS2 gene, which showed structural competition between a G-quadruplex and a hairpin loop. Furthermore, this competition significantly affected transcription efficiency.
- Link information
- ID information
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- DOI : 10.1039/d1cc05523b
- ISSN : 1359-7345
- eISSN : 1364-548X