論文

2022年

Intramolecular G-quadruplex-hairpin loop structure competition of a GC-rich exon region in the TMPRSS2 gene

Chemical Communications
  • Wataru Sugimoto
  • ,
  • Natsuki Kinoshita
  • ,
  • Minori Nakata
  • ,
  • Tatsuya Ohyama
  • ,
  • Hisae Tateishi-Karimata
  • ,
  • Takahito Nishikata
  • ,
  • Naoki Sugimoto
  • ,
  • Daisuke Miyoshi
  • ,
  • Keiko Kawauchi

58
1
開始ページ
48
終了ページ
51
記述言語
掲載種別
研究論文(学術雑誌)
DOI
10.1039/d1cc05523b
出版者・発行元
Royal Society of Chemistry (RSC)

We identified cytosine-rich regions adjacent to guanine-rich regions in the TMPRSS2 gene, which showed structural competition between a G-quadruplex and a hairpin loop. Furthermore, this competition significantly affected transcription efficiency.

リンク情報
DOI
https://doi.org/10.1039/d1cc05523b
URL
http://pubs.rsc.org/en/content/articlepdf/2022/CC/D1CC05523B
ID情報
  • DOI : 10.1039/d1cc05523b
  • ISSN : 1359-7345
  • eISSN : 1364-548X

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