2019年6月
Chemo-enzymatic Synthesis of Ester-Linked Docetaxel-Glycoside Conjugate and its Drug Delivery System Using Hybrid-Bio-Nanocapsules Targeted With Trastuzumab and Cetuximab
NATURAL PRODUCT COMMUNICATIONS
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- 巻
- 14
- 号
- 6
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1177/1934578X19858803
- 出版者・発行元
- SAGE PUBLICATIONS INC
Synthesis of ester-linked glucoside conjugate of docetaxel, 7-propionyldocetaxel 3''-O-alpha-D-glucopyranoside, was carried out by chemo-enzymatic procedures. The EE and LE values for hybrid-bio-nanocapsules of 7-propionyldocetaxel 3''-O-alpha-D-glucopyranoside were much improved rather than those of docetaxel. The hybrid-bio-nanocapsules targeted with trastuzumab and cetuximab, which contained 7-propionyldocetaxel 3''-O-alpha-D-glucopyranoside, showed high in vivo anti-cancer activity, ie, effective suppression of tumor growth, respectively.
- リンク情報
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- DOI
- https://doi.org/10.1177/1934578X19858803
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000475765700067&DestApp=WOS_CPL
- Scopus
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85068592455&origin=inward 本文へのリンクあり
- Scopus Citedby
- https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85068592455&origin=inward
- ID情報
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- DOI : 10.1177/1934578X19858803
- ISSN : 1934-578X
- eISSN : 1555-9475
- SCOPUS ID : 85068592455
- Web of Science ID : WOS:000475765700067