2014年
In Vivo Monitoring of Caspase Activation Using a Fluorescence Resonance Energy Transfer-Based Fluorescent Probe
REGULATED CELL DEATH PT A: APOPTOTIC MECHANISMS
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- 巻
- 544
- 号
- 開始ページ
- 299
- 終了ページ
- 325
- 記述言語
- 英語
- 掲載種別
- 論文集(書籍)内論文
- DOI
- 10.1016/B978-0-12-417158-9.00012-1
- 出版者・発行元
- ELSEVIER ACADEMIC PRESS INC
Caspases, which constitute a family of cysteine proteases, are highly conserved in multicellular organisms and function as a central player in apoptosis. The detection of apoptosis is intrinsically difficult because dying cells are rapidly removed from tissues by phagocytosis. Thus, the development of a method for detecting caspase activation is critical for the in vivo study of apoptosis. In this chapter, we describe a genetically encoded fluorescent probe for live imaging of caspase activation.
- リンク情報
- ID情報
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- DOI : 10.1016/B978-0-12-417158-9.00012-1
- ISSN : 0076-6879
- PubMed ID : 24974295
- Web of Science ID : WOS:000341414700013