2022年1月4日
Total Synthesis of Cryptopleurine and Its Analogues
Synthesis
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- 巻
- 54
- 号
- 10
- 開始ページ
- 2415
- 終了ページ
- 2422
- 記述言語
- 英語
- 掲載種別
- 研究論文（学術雑誌）
- DOI
- 10.1055/a-1730-8628
- 出版者・発行元
- Georg Thieme Verlag KG
Abstract
Total synthesis of phenanthroquinolizidine alkaloid cryptopleurine was achieved in 8 steps from commercially available 2-pyridinecarboxaldehyde and the epoxide derived from methyleugenol. The key intermediate vinyl triflate enables the divergent synthesis of cryptopleurine derivatives by late-stage installation of various substituents on the C-ring.
Total synthesis of phenanthroquinolizidine alkaloid cryptopleurine was achieved in 8 steps from commercially available 2-pyridinecarboxaldehyde and the epoxide derived from methyleugenol. The key intermediate vinyl triflate enables the divergent synthesis of cryptopleurine derivatives by late-stage installation of various substituents on the C-ring.
- リンク情報
- ID情報
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- DOI : 10.1055/a-1730-8628
- ISSN : 0039-7881
- eISSN : 1437-210X