Yasuhiko Kizuka

J-GLOBAL         Last updated: Dec 11, 2019 at 02:48
Yasuhiko Kizuka
Gifu University
Research funding number

Research Interests


Research Areas


Academic & Professional Experience

Apr 2018
Visiting Researcher, Osaka International Cancer Institute
Oct 2017
Associate Professor, G-CHAIN, Gifu University

Published Papers

Nakajima K, Kizuka Y, Yamaguchi Y, Hirabayashi Y, Takahashi K, Yuzawa Y, Taniguchi N
Biochemical and biophysical research communications   495(1) 401-407   Jan 2018   [Refereed]
Imamaki R, Ogawa K, Kizuka Y, Komi Y, Kojima S, Kotani N, Honke K, Honda T, Taniguchi N, Kitazume S
Oncogene   37(31) 4287-4299   May 2018   [Refereed]
Kizuka Y, Mishra S, Yamaguchi Y, Taniguchi N
Cellular immunology   333 80-84   Jul 2018   [Refereed]
Nagae M, Kizuka Y, Mihara E, Kitago Y, Hanashima S, Ito Y, Takagi J, Taniguchi N, Yamaguchi Y
Nature communications   9(1) 3380   Aug 2018   [Refereed]
Harada Y, Suzuki T, Fukushige T, Kizuka Y, Yagi H, Yamamoto M, Kondo K, Inoue H, Kato K, Taniguchi N, Kanekura T, Dohmae N, Maruyama I
Biochimica et biophysica acta. General subjects   1863(4) 681-691   Jan 2019   [Refereed]
Nakano M, Mishra SK, Tokoro Y, Sato K, Nakajima K, Yamaguchi Y, Taniguchi N, Kizuka Y
Molecular & cellular proteomics : MCP   18(10) 2044-2057   Aug 2019   [Refereed]
Taichi M, Nomura S, Nakase I, Imamaki R, Kizuka Y, Ota F, Dohmae N, Kitazume S, Taniguchi N, Tanaka K
Advanced science (Weinheim, Baden-Wurttemberg, Germany)   4(11) 1700147   Nov 2017   [Refereed]
Ota F, Hirayama T, Kizuka Y, Yamaguchi Y, Fujinawa R, Nagata M, Ismanto HS, Lepenies B, Aretz J, Rademacher C, Seeberger PH, Angata T, Kitazume S, Yoshida K, Betsuyaku T, Kida K, Yamasaki S, Taniguchi N
Biochimica et biophysica acta   1862(7) 1592-1601   Apr 2018   [Refereed]
Kizuka Y, Taniguchi N
Glycoconjugate journal   35(4) 345-351   Jun 2018   [Refereed]
Harada Y, Kizuka Y, Tokoro Y, Kondo K, Yagi H, Kato K, Inoue H, Taniguchi N, Maruyama I
FEBS letters   593(9) 942-951   May 2019   [Refereed]
Ota F, Kizuka Y, Nakano M, Yamaguchi Y, Kitazume S, Ookawara T, Taniguchi N
Glycobiology   27(12) 1081-1088   Oct 2017   [Refereed]
Iijima J, Kobayashi S, Kitazume S, Kizuka Y, Fujinawa R, Korekane H, Shibata T, Saitoh SI, Akashi-Takamura S, Miyake K, Miyoshi E, Taniguchi N
Glycobiology   27(11) 1006-1015   Aug 2017   [Refereed]
Kizuka Y, Nakano M, Yamaguchi Y, Nakajima K, Oka R, Sato K, Ren CT, Hsu TL, Wong CH, Taniguchi N
Cell chemical biology   24(12) 1467-1478.e5   Sep 2017   [Refereed]
Kizuka Y, Kitazume S, Taniguchi N
Biochimica et biophysica acta   1861(10) 2447-2454   Apr 2017   [Refereed]
Sakuda K, Kizuka Y, Yamaguchi Y, Tanaka K, Ogiwara K, Segawa T, Hagiwara Y, Matsuo I, Ogawa H, Taniguchi N, Kitazume S
Biochemical and biophysical research communications   487(2) 450-456   May 2017   [Refereed]
Kaburagi T, Kizuka Y, Kitazume S, Taniguchi N
The Journal of biological chemistry   292(6) 2278-2286   Dec 2016   [Refereed]
Ota F, Kizuka Y, Kitazume S, Adachi T, Taniguchi N
FEBS letters   590(19) 3357-3367   Aug 2016   [Refereed]
Gao C, Fujinawa R, Yoshida T, Ueno M, Ota F, Kizuka Y, Hirayama T, Korekane H, Kitazume S, Maeno T, Ohtsubo K, Yoshida K, Yamaguchi Y, Lepenies B, Aretz J, Rademacher C, Kabata H, Hegab AE, Seeberger PH, Betsuyaku T, Kida K, Taniguchi N
American journal of physiology. Lung cellular and molecular physiology   312(2) ajplung.00151.2016-L276   Dec 2016   [Refereed]
Kizuka Y, Funayama S, Shogomori H, Nakano M, Nakajima K, Oka R, Kitazume S, Yamaguchi Y, Sano M, Korekane H, Hsu TL, Lee HY, Wong CH, Taniguchi N
Cell chemical biology   23(7) 782-792   Jul 2016   [Refereed]
Taniguchi N, Takahashi M, Kizuka Y, Kitazume S, Shuvaev VV, Ookawara T, Furuta A
Glycoconjugate journal   33(4) 487-497   Jun 2016   [Refereed]


Yasuhiko Kizuka
Trends in Glycoscience and Glycotechnology   31    Jan 2019
© 2019 FCCA (Forum: Carbohydrates Coming of Age). Sugar analogs can be used as a probe for glycans or as inhibitors of glycosylation. Here, the actions of both existing and our own recently developed fucose analogs are described. Glycans containin...
Yasuhiko Kizuka
Trends in Glycoscience and Glycotechnology   28    Jan 2016
Emi Ito, Ritsuko Oka, Takeo Ishii, Hiroaki Korekane, Ayako Kurimoto, Yasuhiko Kizuka, Shinobu Kitazume, Shigeru Ariki, Motoko Takahashi, Yoshio Kuroki, Kozui Kida, Naoyuki Taniguchi
Data in Brief   5 707-711   Dec 2015
© 2015 The Authors. In order to verify the protein enriched from pooled human sera to be a lung-specific protein surfactant protein-D (SP-D), we performed peptide mass fingerprinting (PMF)-based protein identification. MASCOT search results of the...
Yasuhiko Kizuka
Glycoscience: Biology and Medicine   1129-1134   Jan 2015
© Springer Japan 2015. Regulation of glyco-related genes is a critical factor for glycosylation. Most of the genes involved in glycosylation pathways have been identified, and their expression levels can vary in tissue- or disease-specific manners...
Naoyuki Taniguchi, Yasuhiko Kizuka
Glycoscience: Biology and Medicine   963-969   Jan 2015
© Springer Japan 2015. Mammalian complex N-glycans, first biosynthesized as biantennary glycans, are often modified further by specific GlcNAc transferases (GnTs) and the fucosyltransferase, FUT8, to have multiple branches. Gene-deficient mice for...
Yasuhiko Kizuka
Trends in Glycoscience and Glycotechnology   27    Jan 2015
Yasuhiko Kizuka
Seikagaku   87 381-384   Jan 2015
Yasuhiko Kizuka
Trends in Glycoscience and Glycotechnology   26 167-169   Jan 2014
Yasuhiko Kizuka, Shogo Oka
Handbook of Glycosyltransferases and Related Genes, Second Edition   2 835-847   Jan 2014
© Springer Japan 2014. The human natural killer-1 (HNK-1) carbohydrate epitope, composed of a unique acidic trisaccharide HSO3-3GlcAβ1-3Galβ1-4GlcNAc-, is highly expressed in the nervous system. The HNK-1 epitope is found in N-linked and O-mannose...
Yasuhiko Kizuka, Naoki Nakagawa, Ippei Morita, Shogo Oka
Glycans: Biochemistry, Characterization and Applications   295-312   Feb 2012
GlcAT-P is a glucuronyltransferase that biosynthesizes the HNK-1 (Human Natural Killer-1) carbohydrate involved in synaptic plasticity. Previously, we purified the catalytic domain of recombinant human GlcAT-P and determined its X-ray crystal stru...
Yasuhiko Kizuka, Shogo Oka
Trends in Glycoscience and Glycotechnology   22 194-199   Jan 2010
HNK-1 carbohydrate is highly expressed in the nervous system and is involved in higher-order brain functions such as learning and memory. HNK-1 has a unique structure with sulfated glucuronic acid attached to the non-reducing end of N-acetyllactos...

Research Grants & Projects

Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(B))
Project Year: 2011 - 2013    Investigator(s): Yasuhiko KIZUKA
Aim of this study is to unveil how glycans are expressed in tissue-specific manners. In detail, we focused on a brain-specific glycan, branched O-mannose glycan. As a novel approach, concept and technique of epigenetics were adopted. As a result, ...