持田京子 (Kyoko Mochida) - マイポータル

基本情報

J-GLOBAL ID: 201801011303204130
researchmap会員ID: B000317373

研究分野

ライフサイエンス / 発生生物学 /

論文

USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components

Chiharu Kimura-Yoshida, Kyoko Mochida, Shin-Ichiro Kanno, Isao Matsuo

Communications Biology 5(1) 2022年12月
BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos

Mami Tsume-Kajioka, Chiharu Kimura-Yoshida, Kyoko Mochida, Yoko Ueda, Isao Matsuo

BMC Biology 20(1) 2022年12月
Intrauterine Pressures Adjusted by Reichert’s Membrane Are Crucial for Early Mouse Morphogenesis

Yoko Ueda, Chiharu Kimura-Yoshida, Kyoko Mochida, Mami Tsume, Yoshitaka Kameo, Taiji Adachi, Olivier Lefebvre, Ryuji Hiramatsu, Isao Matsuo

Cell Reports 31(7) 107637-107637 2020年5月査読有り
Publisher Correction: Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis.

Kimura-Yoshida C, Mochida K, Nakaya MA, Mizutani T, Matsuo I

Nature communications 9(1) 4959 2018年11月査読有り
Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis.

Kimura-Yoshida C, Mochida K, Nakaya MA, Mizutani T, Matsuo I

Nature communications 9(1) 4059 2018年10月査読有り
Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure

Chiharu Kimura-Yoshida, Kyoko Mochida, Kristina Ellwanger, Christof Niehrs, Isao Matsuo

EBIOMEDICINE 2(6) 513-527 2015年6月査読有り
External Mechanical Cues Trigger the Establishment of the Anterior-Posterior Axis in Early Mouse Embryos

Ryuji Hiramatsu, Toshiki Matsuoka, Chiharu Kimura-Yoshida, Sung-Woong Han, Kyoko Mochida, Taiji Adachi, Shuichi Takayama, Isao Matsuo

DEVELOPMENTAL CELL 27(2) 131-144 2013年10月査読有り
Brd2 is required for cell cycle exit and neuronal differentiation through the E2F1 pathway in mouse neuroepithelial cells

Mami Tsume, Chiharu Kimura-Yoshida, Kyoko Mochida, Yukinao Shibukawa, Saori Amazaki, Yoshinao Wada, Ryuji Hiramatsu, Kayo Shimokawa, Isao Matsuo

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 425(4) 762-768 2012年9月査読有り
Cell Surface Heparan Sulfate Chains Regulate Local Reception of FGF Signaling in the Mouse Embryo

Kayo Shimokawa, Chiharu Kimura-Yoshida, Naoko Nagai, Kazuhiro Mukai, Kazumi Matsubara, Hideto Watanabe, Yoichi Matsuda, Kyoko Mochida, Isao Matsuo

DEVELOPMENTAL CELL 21(2) 257-272 2011年8月査読有り
Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate

M Yamamoto, N Mine, K Mochida, Y Sakai, Y Saijoh, C Meno, H Hamada

DEVELOPMENT 130(9) 1795-1804 2003年5月査読有り
The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse

M Yamamoto, C Meno, Y Sakai, H Shiratori, K Mochida, Y Ikawa, Y Saijoh, H Hamada

GENES & DEVELOPMENT 15(10) 1242-1256 2001年5月査読有り
Two-step regulation of left-right asymmetric expression of Pitx2: Initiation by nodal signaling and maintenance by Nkx2

H Shiratori, R Sakuma, M Watanabe, H Hashiguchi, K Mochida, Y Sakai, J Nishino, Y Saijoh, M Whitman, H Hamada

MOLECULAR CELL 7(1) 137-149 2001年1月査読有り
Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2

Y Saijoh, H Adachi, R Sakuma, CY Yeo, K Yashiro, M Watanabe, H Hashiguchi, K Mochida, S Ohishi, M Kawabata …

MOLECULAR CELL 5(1) 35-47 2000年1月査読有り
Mouse lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation

C Meno, K Gritsman, S Ohishi, Y Ohfuji, E Heckscher, K Mochida, A Shimono, H Kondoh, WS Talbot, EJ Robertson …

MOLECULAR CELL 4(3) 287-298 1999年9月査読有り
GFR alpha 3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion

J Nishino, K Mochida, Y Ohfuji, T Shimazaki, C Meno, S Ohishi, Y Matsuda, H Fujii, Y Saijoh, H Hamada

NEURON 23(4) 725-736 1999年8月査読有り
Determination of left right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer

H Adachi, Y Saijoh, K Mochida, S Ohishi, H Hashiguchi, A Hirao, H Hamada

GENES & DEVELOPMENT 13(12) 1589-1600 1999年6月査読有り
Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of lefty-1 and lefty-2

Y Saijoh, H Adachi, K Mochida, S Ohishi, A Hirao, H Hamada

GENES & DEVELOPMENT 13(3) 259-269 1999年2月査読有り
lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal

C Meno, A Shimono, Y Saijoh, K Yashiro, K Mochida, S Ohishi, S Noji, H Kondoh, H Hamada

CELL 94(3) 287-297 1998年8月査読有り

MISC

Specific expression of heparan sulfate glycosaminoglycan chains is crucial for local distribution of FGF signaling during mammalian embryogenesis

Kayo Shimokawa, Chiharu Kimura-Yoshida, Kazuhiro Mukai, Saori Amazaki, Kyoko Mochida, Isao Matsuo

DIFFERENTIATION 80 S25-S25 2010年11月
Identification and characterization of a mouse recessive lethal mutation which displays cranial neural tube closure defects

Mami Tsume, Chiharu Kimura-Yoshida, Saori Amazaki, Kayo Shimokawa, Kyoko Mochida, Isao Matsuo

NEUROSCIENCE RESEARCH 68 E130-E130 2010年

共同研究・競争的資金等の研究課題

GRHL3因子による表皮分化におけるパートナー分子の探索

日本学術振興会科学研究費助成事業基盤研究(C) 2023年4月 - 2027年3月

持田京子, 吉田千春
ほ乳動物胚の成長に必要な子宮内環境の解明

日本学術振興会科学研究費助成事業基盤研究(C) 2021年4月 - 2025年3月

上田陽子, 持田京子
上皮の癒合破綻によって発症する二分脊椎や口蓋裂などに共通する病因の解明

日本学術振興会科学研究費助成事業基盤研究(C) 2019年4月 - 2023年3月

持田京子, 吉田千春