森下和広 (Morishita Kazuhiro) - マイポータル

基本情報

所属: 宮崎大学医学部教授

学位: 医学博士(東京大学)

J-GLOBAL ID: 201801009645370134
researchmap会員ID: B000305361

外部リンク: http://www.med.miyazaki-u.ac.jp/home/biochem1/

研究キーワード

研究分野

経歴

2004年4月 - 現在

宮崎大学医学部, 腫瘍生化学分野, 教授
2000年4月 - 2003年3月

宮崎医科大学, 第一生化学部, 教授
1992年10月 - 2000年3月

国立がん研究センター研究所, 生物学部, 主任研究員、室長
1988年8月 - 1992年9月

St Jude Children's Research Hospital,, Department of Biology,, Research fellow, Faculty member
1987年1月 - 1988年7月

Frederick National Cancer Institute,, T-cell leukemogenesis section,, Postdoctral fellow
1980年4月 - 1986年12月

東京大学医科学研究所, 内科、病態薬理研究部、化学研究部、, 研修医、助手、客員研究員

学歴

1974年4月 - 1980年3月

筑波大学, 医学専門学群

受賞

2006年7月

クレディセゾン賞, 日本白血病基金

森下和広

論文

250

Importance of continuous monitoring of bovine leukaemia virus infection on farms in bovine leukaemia virus-endemic areas of Japan.

Chikako Tani, Jiazhou Li, Hirohisa Mekata, Kazuhiro Morishita, Shingo Nakahata

Veterinary record open 12(2) e70014 2025年12月
Anti-transferrin receptor antibody (JST-TFR09/PPMX-T003) induces ferroptosis in adult T-cell leukemia/lymphoma (ATLL) cells

Yanuar Rahmat Fauzi, Shingo Nakahata, Kazuya Shimoda, Tadashi Matsuura, Shinji Hagiwara, Kentaro Inoue, Hiroshi Moritake, Kazuhiro Morishita

Biochemical and Biophysical Research Communications 756 151564-151564 2025年4月
Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2low Adult T-Cell Leukemia/Lymphoma.

Tomonaga Ichikawa, Akira Suekane, Shingo Nakahata, Hidekatsu Iha, Kazuya Shimoda, Takashi Murakami, Kazuhiro Morishita

International journal of molecular sciences 25(5) 2024年2月29日
IMiD/CELMoD-induced growth suppression of adult T-cell leukemia/lymphoma cells via cereblon through downregulation of target proteins and their downstream effectors

Yu Wang, Shunsuke Shimosaki, Emi Ikebe, Hidekatsu Iha, Jun-ichi Yamamoto, Nichole Fife, Tomonaga Ichikawa, Mitsuo Hori, Masao Ogata, Yoshiyuki Tsukamoto …

Frontiers in Oncology 13 2024年1月24日査読有り
Prognostic analysis of smoldering ATLL with skin eruptions based on genomic aberrations

Kosuke Mochida, Shingo Nakahata, Yutaka Suzuki, Kentaro Inoue, Sayaka Moriguchi, Atsushi Yamashita, Masahiro Amano, Kazuhiro Morishita

Journal of Dermatological Science 2023年2月
The CGRP Receptor Antagonist MK0974 Induces EVI1high AML Cell Apoptosis by Disrupting ERK Signaling.

Akira Suekane, Tomonaga Ichikawa, Yusuke Saito, Shingo Nakahata, Kazuhiro Morishita

Anticancer research 42(10) 4743-4752 2022年10月
Oncogenic isoform switch of tumor suppressor BCL11B in adult T-cell leukemia/lymphoma

Happy Kurnia Permatasari, Shingo Nakahata, Tomonaga Ichikawa, Yanuar Rahmat Fauzi, Hiroshi Kiyonari, Kotaro Shide, Takuro Kameda, Kazuya Shimoda, Masaya Ono, Tomohiko Taki …

Experimental Hematology 111 41-49 2022年7月
RAISING is a high-performance method for identifying random transgene integration sites.

Yusaku Wada, Tomoo Sato, Hiroo Hasegawa, Takahiro Matsudaira, Naganori Nao, Ariella L G Coler-Reilly, Tomohiko Tasaka, Shunsuke Yamauchi, Tomohiro Okagawa, Haruka Momose …

Communications biology 5(1) 535-535 2022年6月2日
Prediction of the Adult T-Cell Leukemia Inhibitory Activity of Blueberry Leaves/Stems Using Direct-Injection Electron Ionization-Mass Spectrometry Metabolomics.

Hisahiro Kai, Yoshihito Okada, Yo Goto, Takayuki Nakayama, Kazuhiro Sugamoto, Kenjirou Ogawa, Masao Yamasaki, Kazuhiro Morishita, Koji Matsuno, Hisato Kunitake

Plants (Basel, Switzerland) 11(10) 2022年5月19日
Integrin α6A (ITGA6A)-type Splice Variant in Extracellular Vesicles Has a Potential as a Novel Marker of the Early Recurrence of Pancreatic Cancer.

Takashi Asada, Shingo Nakahata, Yanuar Rahmat Fauzi, Tomonaga Ichikawa, Kentaro Inoue, Nobuhiro Shibata, Yoshiro Fujii, Naoya Imamura, Masahide Hiyoshi, Atsushi Nanashima …

Anticancer research 42(4) 1763-1775 2022年4月
Highly polymerized proanthocyanidins (PAC) components from blueberry leaf and stem significantly inhibit SARS-CoV-2 infection via inhibition of ACE2 and viral 3CLpro enzymes

Kazuhiro Sugamoto, Yuri L. Tanaka, Akatsuki Saito, Yoh Goto, Takayuki Nakayama, Tamaki Okabayashi, Hisato Kunitake, Kazuhiro Morishita

Biochemical and Biophysical Research Communications 2022年4月査読有り
Effective Utilization of Vaccinium virgatum Aiton Stems as Functional Materials: Major Constituent Analysis and Bioactivity Evaluation.

Hisahiro Kai, Kazuhiro Sugamoto, Saki Toshima, Yo Goto, Takayuki Nakayama, Kazuhiro Morishita, Hisato Kunitake

Plants (Basel, Switzerland) 11(4) 2022年2月21日
TAS-116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T-cell leukemia.

Emi Ikebe, Shunsuke Shimosaki, Hiroo Hasegawa, Hidekatsu Iha, Yoshiyuki Tsukamoto, Yu Wang, Daisuke Sasaki, Yoshitaka Imaizumi, Yasushi Miyazaki, Katsunori Yanagihara …

Cancer science 113(2) 684-696 2022年2月
Inhibition of adult T-cell leukemia cell proliferation by polymerized proanthocyanidin from blueberry leaves through JAK proteolysis.

Tomonaga Ichikawa, Kazuhiro Sugamoto, Yasushi Matsuura, Hisato Kunitake, Kazuya Shimoda, Kazuhiro Morishita

Cancer science 2022年1月31日
Role of Mel1/Prdm16 in bone differentiation and morphology.

Kazuko Kaneda-Nakashima, Kaori Igawa, Mathurot Suwanruengsri, Fuke Naoyuki, Tomonaga Ichikawa, Taro Funamoto, Shuji Kurogi, Tomohisa Sekimoto, Yoshihiro Yamashita, Etsuo Chosa …

Experimental cell research 410(2) 112969-112969 2022年1月15日
Antitumor effects of chloroquine/ hydroxychloroquine mediated by inhibition of the NF-κB signaling pathway through abrogation of autophagic p47 degradation in adult T-cell leukemia/lymphoma cells

Yanuar Rahmat Fauzi, Shingo Nakahata, Syahrul Chilmi, Tomonaga Ichikawa, Phawut Nueangphuet, Ryoji Yamaguchi, Tatsufumi Nakamura, Kazuya Shimoda, Kazuhiro Morishita

PLoS ONE 16(8) 2021年8月1日
Commentary on: clinical significance of CD28 gene-related activating alterations in adult T-cell leukaemia/lymphoma.

Shingo Nakahata, Kazuhiro Morishita

British journal of haematology 2020年12月14日
Pathophysiological significance of NDRG2 in cancer development through PP2A phosphorylation regulation.

Kazuhiro Morishita, Shingo Nakahata, Tomonaga Ichikawa

Cancer science 2020年10月30日
Development of anti-human CADM1 monoclonal antibodies as a potential therapy for adult T-cell leukemia/lymphoma.

Syahrul Chilmi, Shingo Nakahata, Yanuar Rahmat Fauzi, Tomonaga Ichikawa, Chikako Tani, Mathurot Suwanruengsri, Ryoji Yamaguchi, Tadashi Matsuura, Gene Kurosawa, Kazuhiro Morishita

International journal of hematology 112(4) 496-503 2020年10月
Corrigendum to "Development of a complete human IgG monoclonal antibody to transferrin receptor 1 targeted for adult T-cell leukemia/lymphomaˮ [Biochem. Biophys. Res. Commun. 485 (1) 2017 144-151].

Shunsuke Shimosaki, Shingo Nakahata, Tomonaga Ichikawa, Akira Kitanaka, Takuro Kameda, Tomonori Hidaka, Yoko Kubuki, Gene Kurosawa, Lilin Zhang, Yukio Sudo …

Biochemical and biophysical research communications 530(2) 486-486 2020年9月17日