2005年
Reconfigurable protein matrices for prolonged neuroblasts patterning and retraction
2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
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- 開始ページ
- 393
- 終了ページ
- 395
- 記述言語
- 英語
- 掲載種別
- 研究論文(国際会議プロシーディングス)
- 出版者・発行元
- IEEE
Here we present long-term patterning and response studies of neuroblasts on arrays of extracellular matrix (ECM) protein lines fabricated by cracking a polymer-supported thin film and selectively depositing proteins inside the cracks. Neuroblasts cultured for five days on the protein matrix switched between spreading and retraction upon changing the protein line width. This technique provides a novel tool to pursue further understanding of the basic mechanisms of neuroblast pathfinding on adhesion and morphology. Biomedical device design will also benefit from materials engineered with the reconfigurable protein patterns.
- リンク情報
- ID情報
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- Web of Science ID : WOS:000234204800122