MISC

2001年9月

Clathrin-mediated endocytosis: membrane factors pull the trigger

TRENDS IN CELL BIOLOGY
  • K Takei
  • ,
  • Haucke, V

11
9
開始ページ
385
終了ページ
391
記述言語
英語
掲載種別
書評論文,書評,文献紹介等
DOI
10.1016/S0962-8924(01)02082-7
出版者・発行元
ELSEVIER SCIENCE LONDON

Clathrin-mediated endocytosis is a vesicular transport event involved in the internalization and recycling of receptors participating in signal transduction events and nutrient import as well as in the reformation of synaptic vesicles. Recent studies in vitro and in living cells have provided a number of new insights into the initial steps of clathrin-coated vesicle formation and the membrane factors involved in this process. The unexpected complexity of these interactions at the cytosol-membrane interface suggests that clathrin-coated vesicle assembly is a highly cooperative process occurring under tight regulatory control. In this review, we focus on the role of membrane proteins and lipids in the nucleation of clathrin-coated pits and provide a hypothetical model for the early steps in clathrin-mediated endocytosis.


リンク情報
DOI
https://doi.org/10.1016/S0962-8924(01)02082-7
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000170532000007&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/S0962-8924(01)02082-7
  • ISSN : 0962-8924
  • Web of Science ID : WOS:000170532000007

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