2001年9月
Clathrin-mediated endocytosis: membrane factors pull the trigger
TRENDS IN CELL BIOLOGY
- ,
- 巻
- 11
- 号
- 9
- 開始ページ
- 385
- 終了ページ
- 391
- 記述言語
- 英語
- 掲載種別
- 書評論文,書評,文献紹介等
- DOI
- 10.1016/S0962-8924(01)02082-7
- 出版者・発行元
- ELSEVIER SCIENCE LONDON
Clathrin-mediated endocytosis is a vesicular transport event involved in the internalization and recycling of receptors participating in signal transduction events and nutrient import as well as in the reformation of synaptic vesicles. Recent studies in vitro and in living cells have provided a number of new insights into the initial steps of clathrin-coated vesicle formation and the membrane factors involved in this process. The unexpected complexity of these interactions at the cytosol-membrane interface suggests that clathrin-coated vesicle assembly is a highly cooperative process occurring under tight regulatory control. In this review, we focus on the role of membrane proteins and lipids in the nucleation of clathrin-coated pits and provide a hypothetical model for the early steps in clathrin-mediated endocytosis.
- リンク情報
- ID情報
-
- DOI : 10.1016/S0962-8924(01)02082-7
- ISSN : 0962-8924
- Web of Science ID : WOS:000170532000007